[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"notifications-list":3,"$f1ksavjf6ncuxw":5},{"data":4},[],{"data":6,"error":11},{"id":7,"documentId":8,"slug":9,"name":10,"medical_code":11,"short_description":12,"alternate_name":11,"disambiguating_description":11,"citations":13,"drugs":24,"specialties":33,"cover":11},818,"dchlkh7n5zhbd7u4wde9njdt","androgen-receptor-agonists","Androgen Receptor Agonists",null,"The androgen receptor is a ligand-activated steroid hormone receptor that acts as a transcription factor: bound by its steroid it works at androgen response elements on target genes, with coactivators and corepressors - ZBTB7A recruiting NCOR1 and NCOR2, for instance - tuning the response, and so regulates proliferation and differentiation in androgen-responsive tissue. Drugs in this class activate it, reproducing the effects of endogenous androgens. A drug belongs here because it is an agonist at the androgen receptor; as MED-RT populates the class that covers testosterone and its esters, the anabolic steroids stanozolol, oxandrolone, oxymetholone, methandrostenolone, methyltestosterone and nandrolone, and danazol.",[14,20],{"claims":15,"source":16,"licence":17,"source_url":18,"retrieved_at":19},"Steroid hormone receptors as ligand-activated transcription factors affecting cellular proliferation and differentiation in target tissues; androgen response elements; modulation by coactivators and corepressors including ZBTB7A recruiting NCOR1 and NCOR2.","UniProtKB P10275","not stated on source page","https:\u002F\u002Frest.uniprot.org\u002Funiprotkb\u002FP10275.json","2026-09-19",{"claims":21,"source":22,"licence":17,"source_url":23,"retrieved_at":19},"Class membership: danazol, fluoxymesterone, methandriol, methandrostenolone, methyltestosterone, nandrolone and esters, oxandrolone, oxymetholone, stanozolol, testosterone and esters - 20 ingredients.","RxNav RxClass class members (MED-RT), classId N0000000146","https:\u002F\u002Frxnav.nlm.nih.gov\u002FREST\u002Frxclass\u002FclassMembers.json?classId=N0000000146&relaSource=MEDRT&rela=has_MoA",[25,29],{"id":26,"documentId":27,"slug":28,"name":28,"active_ingredient":11,"dosage_form":11,"administration_route":11},1808,"shjhrfcqpciiiri42xo8m5y6","stanozolol",{"id":30,"documentId":31,"slug":32,"name":32,"active_ingredient":11,"dosage_form":11,"administration_route":11},1817,"bqk432n9wna6e8263vg162a1","testosterone",[]]