[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$fnuxxzx0b9qnk":3},{"data":4,"error":8},{"id":5,"documentId":6,"heading":7,"body":8,"slug":9,"name":10,"medical_code":8,"short_description":11,"alternate_name":8,"disambiguating_description":8,"citations":12,"drugs":34,"specialties":39,"cover":8},1186,"xm4lzmdojae2m2rcy1ovfh1m","ناهضات مستقبِل الهرمون الوطائي",null,"hypothalamic-hormone-receptor-agonists","Hypothalamic Hormone Receptor Agonists","This class is for agonists at the pituitary receptors that respond to hypothalamic releasing hormones. The best characterised of those receptors is the GnRH receptor, a G protein-coupled receptor whose activation triggers a phosphatidylinositol-calcium second messenger system and stimulates secretion of luteinising hormone and follicle-stimulating hormone. The class should not be treated as a broad parent in practice: the MED-RT class cited holds only triptorelin (as triptorelin, triptorelin acetate, triptorelin pamoate and Trelstar pamoate), whereas the GnRH-specific class N0000175654 holds fourteen members including gonadorelin, goserelin, histrelin and leuprolide. Use the hormone-specific class.",[13,19,23,27],{"claims":14,"source":15,"licence":16,"source_url":17,"retrieved_at":18},"G protein-coupled receptor; phosphatidylinositol-calcium second messenger system; stimulation of LH and FSH secretion","UniProt Gonadotropin-releasing hormone receptor (P30968)","not stated on source page","https:\u002F\u002Frest.uniprot.org\u002Funiprotkb\u002FP30968.json","2026-09-19",{"claims":20,"source":21,"licence":16,"source_url":22,"retrieved_at":18},"the class holds only triptorelin, triptorelin acetate, triptorelin pamoate and Trelstar pamoate","RxClass \u002F MED-RT class members, Hypothalamic Hormone Receptor Agonists (N0000019993)","https:\u002F\u002Frxnav.nlm.nih.gov\u002FREST\u002Frxclass\u002FclassMembers.json?classId=N0000019993&relaSource=MEDRT",{"claims":24,"source":25,"licence":16,"source_url":26,"retrieved_at":18},"the 14 members of the GnRH-specific class","RxClass \u002F MED-RT class members, Gonadotropin Releasing Hormone Receptor Agonists (N0000175654)","https:\u002F\u002Frxnav.nlm.nih.gov\u002FREST\u002Frxclass\u002FclassMembers.json?classId=N0000175654&relaSource=MEDRT",{"claims":28,"source":29,"licence":30,"source_url":31,"harvested_by":32,"retrieved_at":33},"Arabic name (heading)","bAItari term layer and label review (model-written, reviewer-confirmed)","original Arabic name","https:\u002F\u002Fbaitari.vet\u002Fdrug-classes\u002Fhypothalamic-hormone-receptor-agonists","apply-label-arabic.cjs label-core-2026-10-23","2026-10-23",[35],{"id":36,"documentId":37,"slug":38,"name":38,"active_ingredient":8,"dosage_form":8,"administration_route":8},2246,"ooi8bpv5fscbugs521bexq4y","triptorelin",[]]