[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"notifications-list":3,"$f1oeojjlat1f46":5},{"data":4},[],{"data":6,"error":10},{"id":7,"documentId":8,"slug":9,"name":9,"proprietary_name":10,"non_proprietary_name":10,"is_proprietary":10,"active_ingredient":10,"administration_route":10,"available_strength":10,"dosage_form":10,"dose_schedule":10,"drug_unit":10,"is_available_generically":10,"mechanism_of_action":10,"overdosage":10,"warning":10,"species":11,"citations":12,"dose_schedules":23,"available_strengths":36,"label_statements":44,"drug_classes":60,"specialties":66,"medical_conditions":67,"animal_species":68},1743,"f231i1oh3xnuhg06vjwj97f6","mepivacaine",null,[],[13,19],{"source":14,"licence":15,"source_url":16,"harvested_by":17,"retrieved_at":18},"FDA Green Book","US public domain","https:\u002F\u002Fanimaldrugsatfda.fda.gov\u002Fadafda\u002Fapp\u002Fsearch\u002Fpublic\u002FingredientsInformationExcel\u002FSection2ActiveIngredients","load-reference-corpus.cjs","2026-09-07",{"source":20,"licence":21,"source_url":22,"harvested_by":17,"retrieved_at":18},"UK VMD PID","OGL v3.0","https:\u002F\u002Fwww.vmd.defra.gov.uk\u002Fproductinformationdatabase\u002Fdownloads\u002Fvmd_productinformationdatabase.xlsx",[24,31],{"id":25,"dose_text":26,"species":27,"administration_route":28,"limitation":29,"source_label":30},12526,"For nerve block, 3 to 5 milliliters;\nfor epidural anesthesia, 5 to 20 milliliters;\nfor intra-articular anesthesia, 10 to 15 milliliters;\nfor infiltration, as required;\nfor anesthesia of the laryngeal mucosa prior to ventriculectomy by topical spray, 25 to 40 milliliters,\nby infiltration, 20 to 50 milliliters.","Horses","Epidural, Laryngeal, Infiltration, Intra-Articular","Not for use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Carbocaine®-V Sterile Aqueous Solution",{"id":32,"dose_text":33,"species":10,"administration_route":34,"limitation":10,"source_label":35},12527,"Pharmacological studies in various species of animals, including horses, have shown that the drug produces complete and effective anesthesia at dosages that are no more than half those needed when procaine is used.\nThe following dosages have generally proved satisfactory in the horse and are therefore suggested as a guide:\nFor nerve block\n(diagnosis of lameness, firing, pain relief in osteoarthritis, navicular disease)— 3 to 15 mL\nFor epidural anesthesia\n(animal standing)— 5 to 20 mL\nFor intra-articular anesthesia\n(removal of fracture chips, bone and bog spavin, arthritis)— 10 to 15 mL\nFor infiltration\n(alone or in combination with nerve block or intra-articular anesthesia)— as required\nFor anesthesia of the laryngeal mucosa prior to ventriculectomy CARBOCAINE-V Sterile Aqueous Solution may be administered topically or by infiltration or by a combination of the two. For topical application, a total of 25 to 40 mL applied by spray (3 mL\u002Fapplication) is usually adequate. For infiltration, 20 to 50 mL will suffice.","EPIDURAL, INFILTRATION, INTRA-ARTICULAR, TOPICAL","Carbocaine®-V(mepivacaine hydrochloride injection)Sterile Aqueous Solution",[37,41],{"id":38,"strength_text":39,"dosage_form":40,"proprietary_name":30,"species":27,"source_label":30},10819,"Each milliliter (mL) of solution contains 20 milligrams of mepivacaine hydrochloride.","Liquid (Solution)",{"id":42,"strength_text":43,"dosage_form":10,"proprietary_name":10,"species":10,"source_label":35},10820,"20 mg \u002F 1 mL",[45,49,52,56],{"id":46,"kind":47,"statement":48,"species":27,"limitation":29,"source_label":30},18328,"indication","For use as a local anesthetic for infiltration, nerve block, intra-articular and epidural anesthesia and topical and\u002For infiltration anesthesia of the laryngeal mucosa prior to ventriculectomy.",{"id":50,"kind":47,"statement":51,"species":10,"limitation":10,"source_label":35},18329,"CARBOCAINE-V Sterile Aqueous Solution is recommended for infiltration, nerve block, intra-articular and epidural anesthesia for horses. It has also been found useful for topical anesthesia of the laryngeal mucosa prior to ventriculectomy. As with other anesthetics, the dosage varies considerably depending on the anesthetic technique, body area to be desensitized and the surgical procedure.",{"id":53,"kind":54,"statement":55,"species":10,"limitation":10,"source_label":35},18330,"warning","Do not use in horses intended for human consumption. Not for human use. Keep out of reach of children.",{"id":57,"kind":58,"statement":59,"species":10,"limitation":10,"source_label":35},18331,"mechanism_of_action","Mepivacaine hydrochloride is a potent local anesthetic whose effectiveness and safety have been well established in human medicine and dentistry. Laboratory and clinical studies in animals have confirmed its value in veterinary medicine. Its anesthetic activity is two to two and one half times that of procaine, and it is equal to or better than that of lidocaine. The compound has shown excellent tissue compatibility in laboratory animals and in horses. Moderate transient edema at the site of injection may occur in rare instances.\nCARBOCAINE-V Sterile Aqueous Solution produces rapid and marked local anesthesia lasting for several hours. This enables the veterinarian to proceed with intended manipulations without delay and to complete the work under desensitization which is adequate even for prolonged operations. The innate vasoconstrictive activity of CARBOCAINE-V Sterile Aqueous Solution may be enhanced by the addition of epinephrine at 1:100,000. The addition should be carried out aseptically for current use and any unused portion should be discarded.",[61],{"id":62,"documentId":63,"slug":64,"name":65},826,"e0znz56354ufsh7hargcydcb","sodium-channel-interactions","Sodium Channel Interactions",[],[],[]]