[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"notifications-list":3,"$f20up1ta4xp8e0":5},{"data":4},[],{"data":6,"error":11},{"id":7,"documentId":8,"slug":9,"name":10,"proprietary_name":11,"non_proprietary_name":11,"is_proprietary":11,"active_ingredient":11,"administration_route":11,"available_strength":11,"dosage_form":11,"dose_schedule":11,"drug_unit":11,"is_available_generically":11,"mechanism_of_action":11,"overdosage":11,"warning":11,"species":12,"citations":13,"dose_schedules":24,"available_strengths":86,"label_statements":152,"drug_classes":214,"specialties":225,"medical_conditions":226,"animal_species":227},1773,"kdr7bkkfr9m36fetwivfot1g","polymyxin-b","polymyxin b",null,[],[14,20],{"source":15,"licence":16,"source_url":17,"harvested_by":18,"retrieved_at":19},"FDA Green Book","US public domain","https:\u002F\u002Fanimaldrugsatfda.fda.gov\u002Fadafda\u002Fapp\u002Fsearch\u002Fpublic\u002FingredientsInformationExcel\u002FSection2ActiveIngredients","load-reference-corpus.cjs","2026-09-07",{"source":21,"licence":22,"source_url":23,"harvested_by":18,"retrieved_at":19},"UK VMD PID","OGL v3.0","https:\u002F\u002Fwww.vmd.defra.gov.uk\u002Fproductinformationdatabase\u002Fdownloads\u002Fvmd_productinformationdatabase.xlsx",[25,32,38,44,48,52,56,59,61,63,66,69,72,77,81],{"id":26,"dose_text":27,"species":28,"administration_route":29,"limitation":30,"source_label":31},12839,"Rub a small amount into the involved area 1 to 3 times a day. After definite improvement, it may be applied once a day or every other day.","Dogs","Topical","For use in dogs only. Shake drug thoroughly and clean lesion before using. If redness, irritation, or swelling persists or increases, discontinue use and reevaluate diagnosis. Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Forte Topical® Ointment",{"id":33,"dose_text":34,"species":28,"administration_route":35,"limitation":36,"source_label":37},12840,"Instill 5 drops in the ear canal twice daily and massage the ear. Therapy should continue for 7 consecutive days.","Otic","For otic use in dogs only. Do not administer orally. Do not use in dogs with known perforated tympanum. Do not use with drugs known to induce ototoxicity. Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Surolan®",{"id":39,"dose_text":40,"species":28,"administration_route":41,"limitation":42,"source_label":43},12841,"Apply a thin film over the cornea three or four times daily.","Ophthalmic","Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Bacitracin-Neomycin-Polymyxin with Hydrocortisone Acetate Ophthalmic Ointment",{"id":45,"dose_text":46,"species":28,"administration_route":41,"limitation":11,"source_label":47},12842,"Administered topically to the eye 2-4 times daily.","Terramycin®",{"id":49,"dose_text":50,"species":28,"administration_route":41,"limitation":42,"source_label":51},12843,"Instill 1 to 2 drops per eye every 6 hours.","Anaprime® Opthakote Ophthalmic",{"id":53,"dose_text":54,"species":28,"administration_route":41,"limitation":42,"source_label":55},12844,"Apply 2 to 3 drops per eye, every 4 hours.","Anaprime® Ophthalmic Solution",{"id":57,"dose_text":40,"species":58,"administration_route":41,"limitation":42,"source_label":43},12845,"Cats",{"id":60,"dose_text":46,"species":58,"administration_route":41,"limitation":11,"source_label":47},12846,{"id":62,"dose_text":54,"species":58,"administration_route":41,"limitation":42,"source_label":55},12847,{"id":64,"dose_text":46,"species":65,"administration_route":41,"limitation":11,"source_label":47},12848,"Cattle",{"id":67,"dose_text":46,"species":68,"administration_route":41,"limitation":11,"source_label":47},12849,"Sheep",{"id":70,"dose_text":46,"species":71,"administration_route":41,"limitation":11,"source_label":47},12850,"Horses",{"id":73,"dose_text":74,"species":11,"administration_route":75,"limitation":11,"source_label":76},12851,"Shake well before use.\nThe external ear should be thoroughly cleaned and dried before the initiation of treatment. Verify that the eardrum is intact. Instill 5 drops of SUROLAN in the ear canal twice daily and massage the ear. Therapy should continue for 7 consecutive days.","AURICULAR (OTIC)","Surolan™ Rx otic suspension (miconazole nitrate, polymyxin B sulfate, prednisolone acetate)",{"id":78,"dose_text":79,"species":11,"administration_route":80,"limitation":11,"source_label":47},12852,"Terramycin (Oxytetracycline Hydrochloride and Polymyxin B Sulfate Ophthalmic Ointment) should be administered topically to the eye 2–4 times daily.","TOPICAL",{"id":82,"dose_text":83,"species":11,"administration_route":41,"limitation":84,"source_label":85},12853,"Apply a thin film over the cornea 3 or 4 times daily","Federal law restricts this drug to use by or on the order of a licensed veterinarian","Neomycin and Polymyxin B Sulfates, and Bacitracin Zinc Ophthalmic Ointment",[87,91,93,97,99,101,103,105,108,113,116,120,123,126,128,132,134,138,140,143,145,149],{"id":88,"strength_text":89,"dosage_form":90,"proprietary_name":55,"species":28,"source_label":55},11142,"Each milliliter of ophthalmic preparation contains 0.10 milligram flumethasone, 5.0 milligrams neomycin sulfate (3.5 milligrams neomycin base), and 10,000 units of polymyxin B sulfate, without hydroxypropyl methylcellulose.","Liquid",{"id":92,"strength_text":89,"dosage_form":90,"proprietary_name":55,"species":58,"source_label":55},11143,{"id":94,"strength_text":95,"dosage_form":96,"proprietary_name":47,"species":65,"source_label":47},11144,"Each gram of\nointment contains oxytetracycline HCl equivalent to 5 mg of\noxytetracycline and 10,000 units of polymyxin B as the sulfate.","Ointment",{"id":98,"strength_text":95,"dosage_form":96,"proprietary_name":47,"species":68,"source_label":47},11145,{"id":100,"strength_text":95,"dosage_form":96,"proprietary_name":47,"species":71,"source_label":47},11146,{"id":102,"strength_text":95,"dosage_form":96,"proprietary_name":47,"species":28,"source_label":47},11147,{"id":104,"strength_text":95,"dosage_form":96,"proprietary_name":47,"species":58,"source_label":47},11148,{"id":106,"strength_text":107,"dosage_form":90,"proprietary_name":51,"species":28,"source_label":51},11149,"Each milliliter of ophthalmic preparation contains 5.0 milligrams neomycin sulfate (3.5 milligrams neomycin base), 0.10 milligram flumethasone, and 10,000 Units of polymyxin B sulfate.",{"id":109,"strength_text":110,"dosage_form":111,"proprietary_name":112,"species":28,"source_label":112},11150,"Each milliliter of the ophthalmic preparation contains 5.0 milligrams neomycin sulfate (3.5 milligrams neomycin base), and 10,000 Units of polymyxin B sulfate.","Liquid (Solution)","Optiprime® Opthakote Ophthalmic Solution",{"id":114,"strength_text":115,"dosage_form":96,"proprietary_name":31,"species":28,"source_label":31},11151,"Each milliliter of suspension contains 25 milligrams of neomycin sulfate equivalent to 17.5 milligrams of neomycin, 10,000 international units of penicillin G procaine, 5,000 international units of polymyxin B sulfate, 2 milligrams of hydrocortisone acetate, and 1.25 milligrams of hydrocortisone sodium succinate.",{"id":117,"strength_text":118,"dosage_form":96,"proprietary_name":119,"species":28,"source_label":119},11152,"Each gram contains 400 units of bacitracin zinc, 3.5 milligrams of neomycin, and 10,000 units of polymyxin B.","Bac-Neo-Poly Ophthalmic Ointment",{"id":121,"strength_text":118,"dosage_form":96,"proprietary_name":122,"species":58,"source_label":122},11153,"Vetropolycin Ophthalmic Ointment",{"id":124,"strength_text":125,"dosage_form":96,"proprietary_name":43,"species":58,"source_label":43},11154,"Each gram of ointment contains 400 units of bacitracin zinc, 10,000 units of polymyxin B sulfate, 5 milligrams of neomycin sulfate (equivalent to 3.5 milligrams of neomycin base), and 10 milligrams of hydrocortisone acetate.",{"id":127,"strength_text":125,"dosage_form":96,"proprietary_name":43,"species":28,"source_label":43},11155,{"id":129,"strength_text":130,"dosage_form":96,"proprietary_name":131,"species":58,"source_label":131},11156,"Each gram contains 500 units of bacitracin, 3.5 milligrams of neomycin, and 10,000 units of polymyxin B.","Mycitracin® Sterile Ophthalmic Ointment",{"id":133,"strength_text":130,"dosage_form":96,"proprietary_name":131,"species":28,"source_label":131},11157,{"id":135,"strength_text":136,"dosage_form":96,"proprietary_name":137,"species":58,"source_label":137},11158,"Each gram of ointment contains 400 units of bacitracin zinc, 10,000 units of polymyxin B sulfate, 5 milligrams of neomycin sulfate (equivalent to 3.5 milligrams of neomycin base), and 10 milligrams of hydrocortisone.","Cortisporin Veterinary Ophthalmic Ointment",{"id":139,"strength_text":136,"dosage_form":96,"proprietary_name":137,"species":28,"source_label":137},11159,{"id":141,"strength_text":118,"dosage_form":96,"proprietary_name":142,"species":58,"source_label":142},11160,"Neosporin Ophthalmic Ointment",{"id":144,"strength_text":118,"dosage_form":96,"proprietary_name":142,"species":28,"source_label":142},11161,{"id":146,"strength_text":147,"dosage_form":148,"proprietary_name":37,"species":28,"source_label":37},11162,"23 mg\u002FmL miconazole nitrate, 0.5293 mg\u002FmL polymyxin B sulfate, 5 mg\u002FmL prednisolone acetate","Liquid (Suspension)",{"id":150,"strength_text":151,"dosage_form":96,"proprietary_name":85,"species":11,"source_label":85},11163,"Each gram of ointment contains: polymyxin B sulfate 10,000 units, bacitracin zinc 400 units, and neomycin sulfate 5 mg (equivalent to 3.5 mg neomycin base).",[153,157,160,163,166,169,172,175,177,179,181,183,186,188,190,193,196,199,203,207,210],{"id":154,"kind":155,"statement":156,"species":28,"limitation":11,"source_label":47},18727,"indication","Terramycin Ophthalmic Ointment with Polymyxin B Sulfate is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A.\naerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions which\nmay occur secondary to other infectious diseases in the above species.",{"id":158,"kind":155,"statement":159,"species":28,"limitation":42,"source_label":55},18728,"Treatment of the inflammation, edema, and secondary bacterial infections associated with topical ophthalmological conditions of the eye such as corneal injuries, incipient pannus, superficial keratitis, conjunctivitis, acute nongranulomatous anterior uveitis, kerato- conjunctivitis, and blepharitis.",{"id":161,"kind":155,"statement":162,"species":28,"limitation":42,"source_label":51},18729,"For the treatment of bacterial infections associated with topical ophthalmological conditions such as corneal injuries, superficial keratitis, conjunctivitis, keratoconjunctivitis, and blepharitis.",{"id":164,"kind":155,"statement":165,"species":28,"limitation":36,"source_label":37},18730,"For the treatment of canine otitis externa associated with susceptible strains of yeast (Malassezia pachydermatis) and bacteria (Staphylococcus pseudintermedius).",{"id":167,"kind":155,"statement":168,"species":28,"limitation":30,"source_label":31},18731,"Treatment of summer eczema, atopic dermatitis, interdigital eczema and otitis externa caused by bacteria susceptible to neomycin, penicillin, and polymyxin B.",{"id":170,"kind":155,"statement":171,"species":28,"limitation":42,"source_label":119},18732,"Treatment of superficial bacterial infections of the eyelid and conjunctiva of dogs and cats when due to susceptible organisms.",{"id":173,"kind":155,"statement":174,"species":28,"limitation":42,"source_label":43},18733,"Treating acute or chronic conjunctivitis caused by susceptible organisms.",{"id":176,"kind":155,"statement":156,"species":58,"limitation":11,"source_label":47},18734,{"id":178,"kind":155,"statement":159,"species":58,"limitation":42,"source_label":55},18735,{"id":180,"kind":155,"statement":171,"species":58,"limitation":42,"source_label":122},18736,{"id":182,"kind":155,"statement":174,"species":58,"limitation":42,"source_label":43},18737,{"id":184,"kind":155,"statement":185,"species":65,"limitation":11,"source_label":47},18738,"Terramycin® is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A.aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions whichmay occur secondary to other infectious diseases in the above species.",{"id":187,"kind":155,"statement":156,"species":68,"limitation":11,"source_label":47},18739,{"id":189,"kind":155,"statement":156,"species":71,"limitation":11,"source_label":47},18740,{"id":191,"kind":155,"statement":192,"species":11,"limitation":11,"source_label":47},18741,"Terramycin is indicated for the prophylaxis and local treatment of superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms, including infections due to streptococci, rickettsiae, E. coli, and A. aerogenes, such as conjunctivitis, keratitis, pink eye, corneal ulcer, blepharitis in dogs, cats, cattle, sheep, and horses; ocular infections due to secondary bacterial complications of distemper in dogs, and bacterial inflammatory conditions which may occur secondary to other infectious diseases in the above species.",{"id":194,"kind":155,"statement":195,"species":11,"limitation":84,"source_label":85},18742,"For the treatment of superficial bacterial infections of the eyelid and conjunctiva of dogs and cats when due to organisms susceptible to one or more of the antibiotics contained in the ointment",{"id":197,"kind":155,"statement":198,"species":11,"limitation":11,"source_label":76},18743,"SUROLAN is indicated for the treatment of canine otitis externa associated with susceptible strains of yeast (Malassezia pachydermatis) and bacteria (Staphylococcus pseudintermedius).",{"id":200,"kind":201,"statement":202,"species":11,"limitation":11,"source_label":76},18744,"contraindication","SUROLAN is contraindicated in dogs with suspected or known hypersensitivity to miconazole nitrate, polymyxin B sulfate, or prednisolone acetate.\nDo not use in dogs with known perforated tympanum. Do not use with drugs known to induce ototoxicity.",{"id":204,"kind":205,"statement":206,"species":11,"limitation":11,"source_label":47},18745,"warning","Serious, life threatening, hypersensitivity (anaphylactic) reactions have been reported in some cats following application of antibiotic ophthalmic preparations. If your cat has swelling of the face, itching, appears weak, vomits, or has difficulty breathing within 4 hours of application you should discontinue treatment and contact your veterinarian immediately.\nNote: The use of oxytetracycline and other antibiotics may result in an overgrowth of resistant organisms such as Monilia, staphylococci, and other species of bacteria. If new infections due to nonsensitive bacteria or fungi appear during therapy, appropriate measures should be taken.",{"id":208,"kind":205,"statement":209,"species":11,"limitation":11,"source_label":76},18746,"Not for use in humans. Keep this and all drugs out of reach of children.",{"id":211,"kind":212,"statement":213,"species":11,"limitation":11,"source_label":76},18747,"adverse_reaction","In the field study, 161 dogs treated with SUROLAN were included in the safety database. Two dogs experienced reduced hearing at the end of treatment; on follow-up one dog had normal hearing capacity while the other case was lost for follow-up. The owner of another dog reported that on day 4 of treatment, build-up of the medication decreased the dog's hearing. At the end of treatment, this dog had normal hearing as assessed by the investigator. Residue build-up was reported in 1 dog and pain upon drug application in another dog.\nA total of 161 dogs treated with the active control was included in the safety database and adverse reactions were reported in 8 dogs treated with the active control. One dog experienced reduced hearing at the end of treatment. Residue build-up was noted in 1 dog. Four dogs vomited during treatment, 1 dog showed red pustules on the pinna and head shaking was observed in another dog.\nForeign market experience: the following adverse events were reported voluntarily during post-approval use of the product in foreign markets: deafness, reduced hearing, topical hypersensitivity reactions and red blisters on pinna.\nFor a copy of the Safety Data Sheet (SDS), for technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-888-FDA-VETS or www.fda.gov\u002Freportanimalae",[215,220],{"id":216,"documentId":217,"slug":218,"name":219},771,"qy2ycpcfhmvq5c1t29ygoqrw","polymyxins","Polymyxins",{"id":221,"documentId":222,"slug":223,"name":224},863,"ic0horrbvzl4ifl03akj1t02","polymyxin-class-antibacterial","Polymyxin-class Antibacterial",[],[],[]]