[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"notifications-list":3,"$f28ne21hmpu14g":5},{"data":4},[],{"data":6,"error":11},{"id":7,"documentId":8,"slug":9,"name":10,"proprietary_name":11,"non_proprietary_name":11,"is_proprietary":11,"active_ingredient":10,"administration_route":11,"available_strength":11,"dosage_form":11,"dose_schedule":11,"drug_unit":11,"is_available_generically":11,"mechanism_of_action":11,"overdosage":11,"warning":11,"species":12,"citations":19,"dose_schedules":34,"available_strengths":365,"label_statements":526,"drug_classes":926,"specialties":932,"medical_conditions":933,"animal_species":934},1612,"fv4igxlimw43jthm9jhonu63","praziquantel","Praziquantel",null,[13,14,15,16,17,18],"canine","feline","equine","ovine","poultry","fish",[20,26,30],{"source":21,"licence":22,"source_url":23,"harvested_by":24,"retrieved_at":25},"EMA centrally authorised medicines","EMA reuse with attribution","https:\u002F\u002Fwww.ema.europa.eu\u002Fen\u002Fdocuments\u002Freport\u002Fmedicines-output-medicines-report_en.xlsx","load-reference-corpus.cjs","2026-09-07",{"source":27,"licence":28,"source_url":29,"harvested_by":24,"retrieved_at":25},"FDA Green Book","US public domain","https:\u002F\u002Fanimaldrugsatfda.fda.gov\u002Fadafda\u002Fapp\u002Fsearch\u002Fpublic\u002FingredientsInformationExcel\u002FSection2ActiveIngredients",{"source":31,"licence":32,"source_url":33,"harvested_by":24,"retrieved_at":25},"UK VMD PID","OGL v3.0","https:\u002F\u002Fwww.vmd.defra.gov.uk\u002Fproductinformationdatabase\u002Fdownloads\u002Fvmd_productinformationdatabase.xlsx",[35,41,47,52,57,63,69,73,79,83,87,92,95,99,103,107,113,116,122,126,130,134,140,145,151,157,161,165,169,173,177,181,185,189,193,198,201,207,213,217,220,223,228,233,238,242,246,250,254,258,263,267,271,275,279,283,287,291,295,299,303,307,310,313,317,320,324,328,332,336,340,344,348,352,357,361],{"id":36,"dose_text":37,"species":38,"administration_route":39,"limitation":11,"source_label":40},10771,"Administer the entire contents of a provided unit applicator topically once a month at a minimum dose of 0.055 mL\u002Flb (0.12 mL\u002Fkg), which delivers a minimum dose of 0.65 mg\u002Flb (1.44 mg\u002Fkg) esafoxolaner, 0.22 mg\u002Flb (0.48 mg\u002Fkg) eprinomectin, and 4.53 mg\u002Flb (9.98 mg\u002Fkg) praziquantel.","Cats","Topical","NexGard® COMBO",{"id":42,"dose_text":43,"species":38,"administration_route":44,"limitation":45,"source_label":46},10772,"For cats under 5 pounds, 0.2 milliliter (11.4 milligrams);\n5 to 10 pounds, 0.4 milliliter (22.7 milligrams);\n11 pounds and over, 0.6 milliliter (34.1 milligrams) maximum.\nFor subcutaneous or intramuscular injection.","Intramuscular, Subcutaneous","Not intended for use in kittens less than 6 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Prazitech™",{"id":48,"dose_text":49,"species":38,"administration_route":44,"limitation":50,"source_label":51},10773,"May be administered by either the subcutaneous or intramuscular route to cats utilizing the following dosage schedule: Under 5 lbs.—0.2 mL; 5-10 lbs.—0.4 mL; 11 lbs. and over—0.6 mL maximum.","Not intended for use in kittens less than six (6) weeks of age. Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.","Praziquantel Injection",{"id":53,"dose_text":54,"species":38,"administration_route":39,"limitation":55,"source_label":56},10774,"The recommended minimum dose is 1.36 mg\u002Fpound (lb) (3 mg\u002Fkilogram (kg)) emodepside and 5.45 mg\u002F lb (12 mg\u002Fkg) praziquantel applied as a single topical dose.","Federal law restricts this drug to use by or on the order of a licensed veterinarian. Safe use of this product has not been evaluated in cats less that 8 weeks of age or weighing less than 2.2 lbs (1 kg), in cats used for breeding, during pregnancy, or in lactating queens.\nOral ingestion or exposure should be avoided.","Profender™",{"id":58,"dose_text":59,"species":38,"administration_route":60,"limitation":61,"source_label":62},10775,"Centragard™ is dosed at a minimum of 0.055 mL\u002Flb (0.12 mL\u002Fkg), which delivers a minimum dose of 0.23 mg\u002Flb eprinomectin and 4.55 mg\u002Flb praziquantel.","Transdermal","Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Centragard®",{"id":64,"dose_text":65,"species":38,"administration_route":66,"limitation":67,"source_label":68},10776,"4 pounds and under, (11.5 milligrams);\n5 to 11 pounds, (23 milligrams);\nover 11 pounds, (34.5 milligrams).","Oral","Administer directly by mouth or crumbled and in feed. Not intended for use in kittens less than 6 weeks of age.","Droncit® Feline Cestocide Tablets",{"id":70,"dose_text":71,"species":38,"administration_route":66,"limitation":11,"source_label":72},10777,"Cats 4 pounds and under, 11.5 mg; 5 to 11 pounds, 23 mg; over 11 pounds, 34.5 mg.","Praziquantel Tablets",{"id":74,"dose_text":75,"species":76,"administration_route":66,"limitation":77,"source_label":78},10778,"Administer orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg\u002Flb), 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg\u002Flb), and 5 mg of praziquantel per kg (2.27 mg\u002Flb) of body weight, as follows:\n6.0 to 12 pounds- one tablet containing 34 micrograms (mcg) ivermectin, 28.5 milligrams (mg) pyrantel pamoate, and 28.5 mg praziquantel\n12.1 to 25 pounds- one tablet containing 68 mcg ivermectin, 57 mg pyrantel pamoate, and 57 mg praziquantel\n25.1 to 50 pounds- one tablet containing 136 mcg ivermectin, 114 mg pyrantel pamoate, and 114 mg praziquantel\n50.1 to 100 one tablet containing 272 mcg ivermectin, 228 mg pyrantel pamoate, and 228 mg praziquantel","Dogs","Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.","IVERHART MAX® Chew",{"id":80,"dose_text":81,"species":76,"administration_route":66,"limitation":61,"source_label":82},10779,"SENTINEL SPECTRUM is given orally, once a month, at the minimum dosage of 0.23 mg\u002Fpound body weight (0.5 mg\u002Fkg) of milbemycin oxime, 4.55 mg\u002Fpound (10 mg\u002Fkg) of lufenuron, and 2.28 mg\u002Fpound (5 mg\u002Fkg) of praziquantel. For heartworm prevention, give once monthly beginning within 1 month of the dog’s first seasonal exposure to mosquitoes and continuing until at least 6 months after the dog’s last seasonal exposure.","Sentinel® Spectrum®",{"id":84,"dose_text":85,"species":76,"administration_route":44,"limitation":86,"source_label":46},10780,"For dogs 5 pounds and under, 0.3 milliliter (17.0 milligrams);\nfor 6 to 10 pounds, 0.5 milliliter (28.4 milligrams);\nfor 11 to 25 pounds, 1.0 milliliter (56.8 milligrams);\nif over 25 Pounds, 0.2 milliliter (11.4 milligrams) per 5 pounds body weight to a maximum of 3 milliliters (170.4 milligrams). For subcutaneous or intramuscular use.","Not intended for use in puppies less than 4 weeks of age. Federal law restricts the drug to use by or on the order of a licensed veterinarian",{"id":88,"dose_text":89,"species":76,"administration_route":66,"limitation":90,"source_label":91},10781,"5 pounds and under, 1\u002F2 tablet (17 milligrams);\n6 to 10 pounds, 1 tablet (34 milligrams);\n11 to 15 pounds, 1 1\u002F2 tablets (51 milligrams);\n16 to 30 pounds, 2 tablets (68 milligrams);\n31 to 45 pounds, 3 tablets (102 milligrams);\n46 to 60 pounds, 4 tablets (136 milligrams);\nover 60 pounds, 5 tablets maximum (170 milligrams).","Administer directly by mouth or crumbled and in feed. Not intended for use in puppies less than 4 weeks of age. Consult your veterinarian before administering tablets to weak or debilitated animals and for assistance in the diagnosis, treatment, and control of parasitism.","Prazi-C Tablets (OTC)",{"id":93,"dose_text":94,"species":76,"administration_route":66,"limitation":11,"source_label":72},10782,"Dogs 5 pounds (lb) and under, 1\u002F2 tablet (17 mg); 6 to 10 lb, 1 tablet (34 mg); 11 to 15 lb, 1 1\u002F2tablets (51 mg); 16 to 30 lb, 2 tablets (68 mg); 31 to 45 lb, 3 tablets (102 mg); 46 to 60 lb, 4 tablets (136mg); over 60 lb, 5 tablets maximum (170 mg). Administer directly by mouth or crumbled and in feed.",{"id":96,"dose_text":97,"species":76,"administration_route":44,"limitation":98,"source_label":51},10783,"May be administered by either the subcutaneous or intramuscular route to dogs utilizing the following dosage schedule: 5 lbs. and under—0.3 mL; 6-10 lbs.—0.5 mL; 11-25 lbs.—1.0 mL; over 25 lbs.—0.2 mL per 5 lbs. body weight to a maximum of 3 mL.","Not intended for use in puppies less than four (4) weeks of age. Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.",{"id":100,"dose_text":101,"species":76,"administration_route":66,"limitation":11,"source_label":102},10784,"Administer orally once a month, at the minimum dosage of 9 mg\u002Flb (20 mg\u002Fkg) lotilaner, 0.009 mg\u002Flb (0.02 mg\u002Fkg) moxidectin, 2.28 mg\u002Flb (5 mg\u002Fkg) praziquantel, and 2.28 mg\u002Flb (5 mg\u002Fkg) pyrantel (as pamoate salt).","Credelio Quattro™",{"id":104,"dose_text":105,"species":76,"administration_route":66,"limitation":61,"source_label":106},10785,"Administer orally at monthly intervals at the recommended minimum dose level of 100 mg fenbendazole, 6 mcg ivermectin, and 5 mg praziquantel per kg of body weight.","Panacur® Plus",{"id":108,"dose_text":109,"species":110,"administration_route":66,"limitation":111,"source_label":112},10786,"Administer a minimum dose of 5 milligrams\npraziquantel and 5 milligrams pyrantel pamoate per kilogram body weight (2.27 milligrams praziquantel and 2.27 milligrams pyrantel pamoate per pound body weight) according to the dosing tables on labeling.","Dogs (Puppies and Small Dogs 6.0-25 Lbs)","Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness. VIRBANTEL® Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested.","Virbantel®",{"id":114,"dose_text":109,"species":115,"administration_route":66,"limitation":111,"source_label":112},10787,"Dogs (Medium and Large Dogs- Greater than 25 Lbs)",{"id":117,"dose_text":118,"species":119,"administration_route":66,"limitation":120,"source_label":121},10788,"Administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg\u002Flb), 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg\u002Flb) and 5 mg of praziquantel per kg (2.27 mg\u002Flb) of body weight.\n(One table monthly containing 68 mcg ivermectin, 57 mg pyrantel pamoate, and 57 mg praziquantel)","Dogs (12.1 - 25 Lbs)","For oral use in dogs only.\nIVERHART MAX Chewable Tablets are recommended for dogs 8 weeks of age and older. For dogs over 100 lbs, use the appropriate combination of these Chewable Tablets.\nFederal law restricts this drug to use by or on the order of a licensed veterinarian.","IVERHART MAX®",{"id":123,"dose_text":124,"species":125,"administration_route":66,"limitation":120,"source_label":121},10789,"Administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg\u002Flb), 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg\u002Flb) and 5 mg of praziquantel per kg (2.27 mg\u002Flb) of body weight.\n(One tablet monthly containing 34 micrograms (mcg) ivermectin, 28.5 milligrams (mg) pyrantel pamoate, and 28.5 mg praziquantel)","Dogs (6.0 - 12 Lbs)",{"id":127,"dose_text":128,"species":129,"administration_route":66,"limitation":120,"source_label":121},10790,"Administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg\u002Flb), 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg\u002Flb) and 5 mg of praziquantel per kg (2.27 mg\u002Flb) of body weight.\n(One tablet monthly containing 272 mcg ivermectin, 228 mg pyrantel pamoate, and 228 mg praziquantel)","Dogs (50.1 - 100 Lbs)",{"id":131,"dose_text":132,"species":133,"administration_route":66,"limitation":120,"source_label":121},10791,"Administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg\u002Flb), 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg\u002Flb) and 5 mg of praziquantel per kg (2.27 mg\u002Flb) of body weight.\n(One tablet monthly containing 136 mcg ivermectin, 114 mg pyrantel pamoate, and 114 mg praziquantel)","Dogs (25.1 - 50 Lbs)",{"id":135,"dose_text":136,"species":137,"administration_route":66,"limitation":138,"source_label":139},10792,"200 microgram per kilogram ivermectin (91 microgram per pound) and 1.5 milligram per kilogram praziquantel (.68 milligram per pound) body weight.","Horses","For oral use in horses only. Do not use in horses intended for human consumption.\nThis product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result","Equimax®",{"id":141,"dose_text":142,"species":137,"administration_route":66,"limitation":143,"source_label":144},10793,"200 mcg\u002Fkg ivermectin (91 mcg\u002Flb) and 2.5 mg\u002Fkg praziquantel (1.14 mg\u002Flb).","Do not use in horses intended for human consumption.","Duocare™",{"id":146,"dose_text":147,"species":148,"administration_route":66,"limitation":149,"source_label":150},10794,"Administer by mouth as a single dose: 0.4 milligram moxidectin per kilogram and 2.5 milligrams praziquantel per kilogram (2.2 pounds) body weight.","Horses and Ponies","For oral use in horses and ponies 6 months of age and older. Do not use in horses intended for human consumption.QUEST PLUS Gel has been formulated specifically for use in horses and ponies only.Reproductive safety studies on breeding stallions have not been conducted.This product should not be used in other animal species as severe adverse reactions, including fatalities in dogs, may result.Extreme caution should be used when administering the product to foals, young and miniature horses, as overdosage may result in serious adverse reactions. Do not use in sick, debilitated, or underweight animals.","Quest® Plus Gel",{"id":152,"dose_text":153,"species":154,"administration_route":66,"limitation":155,"source_label":156},10795,"0.5 Tablet No.1","Dogs: Weighing 2 to 4 pounds (0.9 to 1.8 kilograms)","Do not use in pregnant animals. Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age. Federal law restricts this drug to use by or on the order of a licensed veterinarian","Drontal™ Plus",{"id":158,"dose_text":159,"species":160,"administration_route":66,"limitation":155,"source_label":156},10796,"1 tablet No.1","Dogs: Weighing 5 to 7 pounds (2.3 to 3.2 kilograms):",{"id":162,"dose_text":163,"species":164,"administration_route":66,"limitation":155,"source_label":156},10797,"1.5 tablet No.1","Dogs: Weighing 8 to 12 pounds (3.6 to 5.4 kilograms)",{"id":166,"dose_text":167,"species":168,"administration_route":66,"limitation":155,"source_label":156},10798,"2 tablets No.1","Dogs: Weighing 13 to 18 pounds (5.9 to 8.2 kilograms)",{"id":170,"dose_text":171,"species":172,"administration_route":66,"limitation":155,"source_label":156},10799,"2.5 tablets No.1","Dogs: Weighing 19 to 25 pounds (8.6 to 11.4 kilograms)",{"id":174,"dose_text":175,"species":176,"administration_route":66,"limitation":155,"source_label":156},10800,"1 tablet No.2","Dogs: Weighing 26 to 30 pounds (11.8 to 13.6 kilograms)",{"id":178,"dose_text":179,"species":180,"administration_route":66,"limitation":155,"source_label":156},10801,"1.5 tablets No.2","Dogs: Weighing 31 to 44 pounds (14.1 to 20.0 kilograms)",{"id":182,"dose_text":183,"species":184,"administration_route":66,"limitation":155,"source_label":156},10802,"2.0 tablets No.2 or 1.0 Tablet No. 3","Dogs: Weighing 45 to 60 pounds (20.4 to 27.2 kilograms)",{"id":186,"dose_text":187,"species":188,"administration_route":66,"limitation":155,"source_label":156},10803,"1.5 tablets No. 3","Dogs: Weighing 61 to 90 pounds (27.7 to 40.9 kilograms)",{"id":190,"dose_text":191,"species":192,"administration_route":66,"limitation":155,"source_label":156},10804,"2 tablets No. 3","Dogs: Weighing 91 to 120 pounds (41.3 to 54.5 kilograms)",{"id":194,"dose_text":153,"species":195,"administration_route":66,"limitation":196,"source_label":197},10805,"Dogs: Weighing 2 to 4 pounds","Do not use in dogs weighing less than 2 pounds (0.9 kilogram) or in puppies less than 3 weeks of age.\nFasting is neither necessary nor recommended.\nConsult your veterinarian for assistance in the diagnosis, treatment and control of parasitism.\nConsult your veterinarian before administering the tablets to weak or debilitated animals.\nDo not deworm a dog or puppy that is sick.\nConsult your veterinarian for diagnosis of the illness and appropriate care.","Quad Dewormer",{"id":199,"dose_text":159,"species":200,"administration_route":66,"limitation":196,"source_label":197},10806,"Dogs: Weighing 5 to 7 pounds",{"id":202,"dose_text":203,"species":204,"administration_route":66,"limitation":205,"source_label":206},10807,"Administer a minimum dose of 2.27 mg praziquantel and 9.2 pyrantel pamoate per pound of bodyweight according to the dosing tables on labeling.","Cats and Kittens (Greater Than 2 Months of Age Or At Least 2 Lbs)","May be given directly by mouth or in a small amount of food. Do not withhold food prior to or after treatment. If reinfection occurs, treatment may be repeated. Consult your veterinarian before giving to sick or pregnant animals. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. Not for use in kittens less than 2 months of age or weighing less than 2.0 pounds.","Drontal™ Tablets",{"id":208,"dose_text":209,"species":210,"administration_route":66,"limitation":211,"source_label":212},10808,"10 milligrams of febantel and 1 milligram of praziquantel per kilogram of body weight (1 gram of paste per 7.5 pounds body weight) administered by mouth or in the food once daily for 3 days.","Dogs (over 6 months of age)","Do not use in pregnant animals. Federal law restricts this drug to use by or on the order of a licensed veterinarian. Consider alternative therapy or use with caution in animals with pre-existing liver or kidney dysfunction.","Vercom Paste Anthelmintic",{"id":214,"dose_text":215,"species":216,"administration_route":66,"limitation":211,"source_label":212},10809,"15 milligrams of febantel and 1.5 milligrams of praziquantel per kilogram of body weight (1 gram of paste per 5 pounds body weight) administered by mouth on a full stomach once daily for 3 days.","Dogs (puppies less than 6 months of age)",{"id":218,"dose_text":209,"species":219,"administration_route":66,"limitation":211,"source_label":212},10810,"Cats (over 6 months of age)",{"id":221,"dose_text":215,"species":222,"administration_route":66,"limitation":211,"source_label":212},10811,"Cats (kittens under 6 months of age)",{"id":224,"dose_text":225,"species":226,"administration_route":66,"limitation":61,"source_label":227},10812,"Administer orally, once a month, a minimum dosage of 0.23 mg per pound (mg\u002Flb) of body weight (0.5 mg per kilogram (mg\u002Fkg)) milbemycin oxime and 2.28 mg\u002Flb of body weight (5 mg\u002Fkg) praziquantel.","Dogs (2 lbs or greater and 6 weeks or older)","INTERCEPTOR™ PLUS",{"id":229,"dose_text":230,"species":11,"administration_route":231,"limitation":11,"source_label":232},10813,"NexGard® COMBO is dosed at a minimum of 0.055 mL\u002Flb (0.12 mL\u002Fkg), which delivers a minimum dose of 0.65 mg\u002Flb (1.44 mg\u002Fkg) esafoxolaner, 0.22 mg\u002Flb (0.48 mg\u002Fkg) eprinomectin, and 4.53 mg\u002Flb (9.98 mg\u002Fkg) praziquantel.\nFor heartworm disease prevention, apply once monthly for at least three months after last exposure to mosquitoes (see Effectiveness).\nAdminister the entire contents of a NexGard® COMBO unit applicator topically once a month as specified in the following table:\nDosing Schedule\nCat Weight (lb)\nVolume (mL)\nEsafoxolaner (mg)\nEprinomectin (mg)\nPraziquantel (mg)\n1.8- 5.5\n0.3\n3.6\n1.2\n24.9\n5.6-16.5\n0.9\n10.8\n3.6\n74.7\n16.6-22\n0.3 + 0.9\n14.4\n4.8\n99.6\n22.1-33\n0.9 + 0.9\n21.6\n7.2\n149.4\nA veterinarian or veterinary technician should demonstrate or instruct the pet owner regarding the appropriate technique for applying NexGard® COMBO topically to cats and kittens prior to first use.\nKeep product in original packaging until ready to use.\n1.Use scissors to cut the blister along the dotted line.\n2.Then pull the lid away.\n3.Remove the applicator from the package and hold it upright. Pull back the plunger slightly.\n4.Twist and pull off the cap.\n5.Part the hair on the midline of the neck, between the base of the skull and the shoulder blades until the skin is visible. Place the tip of the applicator on the skin and apply the entire contents directly onto the skin in one spot. The product should be applied to dry skin on an area where the cat cannot lick it off. If the weight of the cat requires a second application, apply the contents in the same manner as described above in the same location.\n6.Wash hands after use with soap and water.\nHeartworm Prevention:\nFor the prevention of heartworm disease, NexGard® COMBO should be administered once a month year-round. At a minimum, administration of NexGard® COMBO should start at least 1 month before the cat’s first expected exposure to mosquitoes and monthly thereafter until at least 3 months after the cat’s last seasonal exposure to mosquitoes (see Effectiveness). If a dose is missed and a 30-day interval between doses is exceeded, administer NexGard® COMBO immediately and resume the monthly dosing schedule. Treatment with fewer than 3 monthly doses may not provide complete heartworm prevention. When replacing another monthly heartworm preventive product in a heartworm prevention program, the first treatment with NexGard® COMBO should be given within one month of the last dose of the former medication. At the discretion of the veterinarian, cats older than 6 months of age may be tested to determine the presence of existing heartworm infection before treatment with NexGard® COMBO. Cats already infected with adult heartworms can be given NexGard® COMBO monthly to prevent further infections.\nFlea Treatment and Prevention:\nFor the treatment and prevention of flea infestations, the use of NexGard® COMBO may begin at any time of year. NexGard® COMBO should be administered year-round at monthly intervals or begin at least one month before fleas become active. However, an environmental infestation may persist for a short time after beginning treatment with NexGard® COMBO because of the development of adult fleas from eggs that were laid prior to the initiation of treatment.\nTick Treatment and Control:\nFor the treatment and control of infestations with Ixodes scapularis and Amblyomma americanum, the use of NexGard® COMBO may begin at any time of year. NexGard® COMBO should be administered year-round at monthly intervals or begin at least one month before the ticks become active.\nTreatment and Control of Roundworms, Hookworms, and Tapeworms:\nNexGard® COMBO provides treatment and control of roundworms (adult and fourth stage larval Toxocara cati), hookworms (adult and fourth stage larval Ancylostoma tubaeforme; adult Ancylostoma braziliense), and tapeworms (Dipylidium caninum). For the treatment of hookworm, roundworms and tapeworm infections, NexGard® COMBO should be administered once as a single dose. Monthly use of NexGard® COMBO will control any subsequent infections. Cats may be exposed to and can become infected with roundworms, hookworms, and tapeworms throughout the year, regardless of season or climate.","TOPICAL","NexGard® COMBO (esafoxalaner, eprinomectin, and praziquantel topical solution)",{"id":234,"dose_text":235,"species":11,"administration_route":236,"limitation":11,"source_label":237},10814,"Credelio Quattro\u002FCredelio Quattro-CA1 is given orally at the minimum dosage of 9 mg\u002Flb (20 mg\u002Fkg) lotilaner, 0.009 mg\u002Flb (0.02 mg\u002Fkg) moxidectin, 2.28 mg\u002Flb (5 mg\u002Fkg) praziquantel, and 2.28 mg\u002Flb (5 mg\u002Fkg) pyrantel (as pamoate salt). Credelio Quattro\u002FCredelio Quattro-CA1 must be administered with food (see\nClinical Pharmacology\n). Care should be taken to ensure that the dog consumes the complete dose and that part of the dose is not lost or refused. If vomiting occurs within an hour after administration, readminister a new dose of Credelio Quattro\u002FCredelio Quattro-CA1.\nCredelio Quattro:\nCredelio Quattro is given once a month. If a dose is missed, give Credelio Quattro immediately and resume a monthly dosing schedule.\nDosing Schedule:\n*As pamoate salt\nBody Weight (lbs)\nTablets to Administer\nLotilaner\nper Tablet (mg)\nMoxidectin\nper Tablet (mg)\nPraziquantel\nper Tablet (mg)\nPyrantel*\nper Tablet (mg)\n3.3 – 6\n1\n56.25\n0.056\n14.25\n14.25\n6.1 – 12\n1\n112.5\n0.113\n28.5\n28.5\n12.1 – 25\n1\n225\n0.225\n57\n57\n25.1 – 50\n1\n450\n0.45\n114\n114\n50.1 – 100\n1\n900\n0.9\n228\n228\n> 100\nAdminister the appropriate combination of tablets\nHeartworm Prevention\nCredelio Quattro should be administered year-round at monthly intervals or at least within 1 month of the animal’s first seasonal exposure to mosquitoes and continuing until at least 1 month after the dog’s last seasonal exposure. If a dose is missed, give Credelio Quattro immediately and resume monthly dosing. When replacing a monthly heartworm preventive product, Credelio Quattro should be given within 1 month of the last dose of the former medication.\nIntestinal Nematode and Cestode Treatment and Control\nCredelio Quattro should be administered as a single dose for the treatment of roundworm, hookworm, and tapeworm infections. Monthly use of Credelio Quattro will control any subsequent infections. Dogs may be exposed to and can become infected with gastrointestinal worms throughout the year, regardless of season or climate. Clients should be advised of appropriate measures to prevent reinfection of their dog with intestinal parasites.\nFlea Treatment and Prevention\nTreatment with Credelio Quattro should be administered year-round at monthly intervals or started at least 1 month before fleas become active. To minimize the likelihood of flea re-infestation, it is important to treat all dogs and cats within a household with a flea control product.\nTick Treatment and Control\nTreatment with Credelio Quattro can begin at any time of the year. Credelio Quattro should be administered year-round at monthly intervals or started at least 1 month before ticks become active.\nCredelio Quattro-CA1:\nNew World Screwworm (NWS) Myiasis Treatment\nA single dose of Credelio Quattro-CA1 is reasonably expected to treat C. hominivorax present at the time of treatment. Re-infestation with C. hominivorax may occur sooner than one month. Treatment should be used in conjunction with the mechanical removal of larvae (live and dead) remaining in the wound after treatment (see\nPRECAUTIONS\n).","ORAL","Credelio Quattro™ CredelioQuattro™-CA1(lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets)",{"id":239,"dose_text":240,"species":11,"administration_route":236,"limitation":11,"source_label":241},10815,"IVERHART MAX Chew should be administered orally at monthly intervals and the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg\u002F lb), 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg\u002Flb), and 5 mg of praziquantel per kg (2.27 mg\u002Flb) of body weight, as follows:\nDosing Schedule\nDog Weight\nPounds\nChew\nper\nMonth\nChew\nSize\nIvermectin\nContent\nPyrantel\nPamoate\nContent\nPraziquantel\nContent\n6.0 to 12\n1\nToy\n34 mcg\n28.5 mg\n28.5 mg\n12.1 to 25\n1\nSmall\n68 mcg\n57 mg\n57 mg\n25.1 to 50\n1\nMedium\n136 mcg\n114 mg\n114 mg\n50.1 to 100\n1\nLarge\n272 mcg\n228 mg\n228 mg\nIVERHART MAX Chew is recommended for dogs 8 weeks of age or older. For dogs over 100 lbs, use the appropriate combination of these chews. Remove only one dose at a time from the packaging. Return the remaining chew(s) to their box to protect from light. The chew can be offered to the dog by hand or added, intact, to a small amount of dog food. Care should be taken to ensure that the dog consumes the complete dose. The treated dog should be observed for a few minutes after administration to confirm that none of the dose has been lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.\nIVERHART MAX Chew should be given at monthly intervals during the period of the year when mosquitoes (vectors), potentially carrying infective heartworm larvae, are active. The initial dose must be given within a month (30 days) after the dog’s first exposure to mosquitoes. The final dose must be given within a month (30 days) after the dog’s last exposure to mosquitoes.\nWhen replacing another heartworm preventative product in a heartworm disease prevention program, the first dose of IVERHART MAX Chew must be given within a month (30 days) after the last dose of the former medication. A heartworm test should be performed prior to and 6 months after switching heartworm preventative products.\nIf the interval between doses exceeds a month (30 days), the effectiveness of ivermectin can be reduced. Therefore, for optimal performance, the chew must be given once a month on or about the same day of the month. If treatment is delayed, whether by a few days or many, immediate treatment with IVERHART MAX Chew and resumption of the recommended dosing regimen will minimize the opportunity for the development of adult heartworms.","IVERHART MAX® Chew (ivermectin\u002Fpyrantel pamoate\u002Fpraziquantel)",{"id":243,"dose_text":244,"species":11,"administration_route":236,"limitation":11,"source_label":245},10816,"This syringe contains sufficient paste to treat one 1320-lb horse at the recommended dose rate of 91 mcg ivermectin per lb (200 mcg\u002Fkg) and 0.68 mg praziquantel per lb (1.5 mg\u002Fkg) of body weight. Each weight marking on the syringe plunger delivers enough paste to treat 220 lb (100 kg) of body weight.\n1. While holding plunger, turn the knurled ring on the plunger 1\u002F4 turn to the left and slide it so the side nearest the barrel is at the prescribed weight marking.\n2. Lock the ring in place by making a 1\u002F4 turn to the right.\n3. Make sure that the horse’s mouth contains no feed.\n4. Remove the cover from the tip of the syringe.\n5. Insert the syringe tip into the horse’s mouth at the space between the teeth.\n6. Depress the plunger as far as it will go, depositing paste on the back of the tongue.\n7. Immediately raise the horse’s head for a few seconds after dosing.\nDo not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the development of parasite resistance.\nParasite Control Program: All horses should be included in a regular parasite control program with particular attention being paid to\nmares, foals, and yearlings. Foals should be treated initially at 4 weeks of age, and routine treatment repeated as appropriate. Consult\nyour veterinarian for a control program to meet your specific needs. EQUIMAX Oral Paste effectively controls gastrointestinal\nnematodes, cestodes and bots of horses. Regular treatment will reduce the chances of colic caused by Anoplocephala perfoliata and\nverminous arteritis caused by Strongylus vulgaris.\nProduct Advantages: Broad-spectrum Control: EQUIMAX Oral Paste kills important internal parasites, including tapeworms, bots and\nthe arterial stages of S. vulgaris, with a single dose. EQUIMAX Oral Paste contains two potent antiparasitic agents that are neither\nbenzimidazoles nor organophosphates.","Equimax®(ivermectin 1.87% \u002F praziquantel 14.03%) Oral Paste Anthelmintic and Boticide",{"id":247,"dose_text":248,"species":11,"administration_route":231,"limitation":11,"source_label":249},10817,"The recommended minimum dose is 1.36 mg\u002Flb (3 mg\u002Fkg) emodepside + 5.45 mg\u002Flb (12 mg\u002Fkg) praziquantel as a single topical dose. A single treatment is effective and a second treatment should not be necessary. If re-infection occurs, the product can be re-applied after 30 days.\n1.Select the package that correctly corresponds with the body weight of the cat. (See Table below.)\n* Cats over 17.6 lbs should be treated with the appropriate combination of tubes.\nCat Weight*\nProfender Topical Solution\nVolume (mL)\nEmodepside (mg)\nPraziquantel (mg)\n2.2-5.5 lbs.\nSmall\n0.35\n7.5\n30.0\n>5.5-11 lbs.\nMedium\n0.70\n15.0\n60.1\n>11-17.6 lbs.\nLarge\n1.12\n24.0\n96.1\n2.Remove one unit dose tube from the package.\n3.While holding the tube in an upright position, remove the cap from the tube.\n4.Turn the cap over and place the other end of cap onto the tip of the tube.\n5.Twist the cap to break the seal and then remove cap from the tube.\n6.Part the hair on the back of the cat’s neck at the base of the head, until the skin is visible.\n7.The ensure the entire contents of the tube are administered, place the tip of the tube on the skin and squeeze the entire contents directly onto the skin. Lift tube away from the skin before releasing pressure on the tube.\nDo not apply to broken skin or if hair coat is wet. Do not get this product in the cat’s mouth or eyes or allow the cat to lick the application site for one hour. Oral exposure can cause salivation and vomiting. Treatment at the base of the head will minimize the opportunity for ingestion while grooming. In households with multiple pets, keep animals separated to prevent licking of the application site.\nStiff hair, a damp appearance of the hair, or a slight powdery residue may be observed at the treatment site. These effects are temporary and do not affect the safety or effectiveness of the product.","Elanco™ Topical Solution profender™ (emodepside\u002Fpraziquantel)",{"id":251,"dose_text":252,"species":11,"administration_route":236,"limitation":11,"source_label":253},10818,"Dosage and Administration: SENTINEL SPECTRUM Chews should be administerd orally, once every month, at the minimum dosage of 0.23 mg\u002Flb (0.5 mg\u002Fkg) milbemycin oxime, 4.55 mg\u002Flb (10 mg\u002Fkg) lufenuron, and 2.28 mg\u002Flb (5 mg\u002Fkg) praziquantel. For heartworm prevention, give once monthly for at least 6 months after exposure to mosquitoes (see\nEFFECTIVENESS\n).\nDosage Schedule\nBody Weight\nMilbemycin Oxime per chewable\nLufenuron per chewable\nPraziquantel per chewable\nNumber of chewables\n2 to 8 lbs.\n2.3 mg\n46 mg\n22.8 mg\nOne\n8.1 to 25 lbs.\n5.75 mg\n115 mg\n57 mg\nOne\n25.1 to 50 lbs.\n11.5 mg\n230 mg\n114 mg\nOne\n50.1 to 100 lbs.\n23.0 mg\n460 mg\n228 mg\nOne\nOver 100 lbs.\nAdminister the appropriate combination of chewables\nTo ensure adequate absorption, always administer SENTINEL SPECTRUM Chews to dogs immediately after or in conjunction with a normal meal.\nSENTINEL SPECTRUM Chews may be offered to the dog by hand or added to a small amount of dog food. The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed a few minutes after administration to ensure that no part of the dose is lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.","sentinel® spectrum® chews (milbemycin oxime • lufenuron • praziquantel)",{"id":255,"dose_text":256,"species":11,"administration_route":236,"limitation":11,"source_label":257},10819,"INTERCEPTOR PLUS should be administered orally, once every month, at the minimum dosage of 0.23 mg\u002Flb (0.5 mg\u002Fkg) milbemycin oxime, and 2.28 mg\u002Flb (5 mg\u002Fkg) praziquantel. For heartworm prevention, give once monthly for at least 6 months after exposure to mosquitoes (see\nEFFECTIVENESS\n).\nDosage Schedule\nBody Weight\nMilbemycin Oxime per chewable\nPraziquantel per chewable\nNumber of chewables\n2 to 8 lbs.\n2.3 mg\n22.8 mg\nOne\n8.1 to 25 lbs.\n5.75 mg\n57 mg\nOne\n25.1 to 50 lbs.\n11.5 mg\n114 mg\nOne\n50.1 to 100 lbs.\n23 mg\n228 mg\nOne\nOver 100 lbs.\nAdminister the appropriate combination of chewables.\nINTERCEPTOR PLUS may be offered to the dog by hand or added to a small amount of dog food. The chewables should be administered in a manner that encourages the dog to chew, rather than to swallow without chewing. Chewables may be broken into pieces and fed to dogs that normally swallow treats whole. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes after administration to ensure that no part of the dose is lost or rejected. If it is suspected that any of the dose has been lost, redosing is recommended.","INTERCEPTOR™",{"id":259,"dose_text":260,"species":11,"administration_route":261,"limitation":11,"source_label":262},10820,"Droncit (praziquantel) Injectable Cestocide may be administered by either the subcutaneous or intramuscular route to dogs and cats. The recommended dosage of praziquantel varies according to body weight. Smaller animals require a relatively larger dosage. The optimum dosage for each individual animal will be achieved by utilizing the following dosage schedule.\nDOGS AND PUPPIES†\n† Not intended for use in puppies less than four (4) weeks of age.\nDogs:\n5 lbs. and under\n0.3 mL\n6-10 lbs.\n0.5 mL\n11-25 lbs.\n1.0 mL\nover 25 lbs.\n0.2 mL \u002F5 lbs.\nbody weight to a\nmaximum of 3 mL\nCATS AND KITTENS††\n†† Not intended for use in kittens less than six (6) weeks of age.\nCats:\nUnder 5 lbs.\n0.2 mL\n5-10 lbs.\n0.4 mL\n11 lbs. and over\n0.6 mL maximum\n10 mL: Use within 6 months of first puncture and puncture a maximum of 25 times. Any product remaining after 25 punctures or more than 6 months after initial puncture should be discarded.\n50 mL: Use within 6 months of first puncture and puncture a maximum of 90 times. Any product remaining after 90 punctures or more than 6 months after initial puncture should be discarded.","INTRAMUSCULAR, SUBCUTANEOUS","Elanco DroncitTM (praziquantel) Injectable Cestocide For Dogs And Cats",{"id":264,"dose_text":265,"species":11,"administration_route":236,"limitation":11,"source_label":266},10821,"Replace 3\u002F4 of the aquarium water prior to beginning treatment with dactymor. Add 5 ml (= 100 drops) of dactymor for every 100 l of aquarium water and stir the aquarium water to disperse the product. Switch off UV-lamps. After 6 hours treatment a replacement of minimum 3\u002F4 of the aquarium water is required. On the following day change half of the aquarium water. A single treatment is generally adequate for skin worms and tapeworms. However, trematode eggs are not affected. Therefore, when treating trematodes, the treatment should be repeated twice, waiting approx. one week between each treatment (for coldwater ornamental fish, wait approx. one-and-one-half weeks between treatments).\nThe aquarium should be continuously monitored during the treatment with dactymor. In aquariums containing a large biomass (microorganisms in filters, ground, etc.) the use of dactymor may result in an increase in bacterial growth. In turn this can lead to an oxygen depletion. Immediately change the aquarium water if signs of bacterial turbidity or indications of oxygen depletion are observed.","DACTYMOR",{"id":268,"dose_text":269,"species":11,"administration_route":236,"limitation":11,"source_label":270},10822,"DOSAGE AND ADMINISTRATION:\nDog Worm Tabs Chewable Tablets for Dogs may be given directly in the mouth or offered in a small amount of food. You should weigh your dog to make sure you are using the right size and number of tablets. Administer to dogs and puppies* only as follows:\n*NOT FOR USE IN PUPPIES LESS THAN 3 WEEKS OF AGE OR DOGS WEIGHING LESS THAN 2 LBS.\nDog Worm Tabs\nChewable Tablets for Dogs\nDosage Charts\nfor Puppies and Small Dogs*\n(2 - 25 lbs.)\nBody Wt.\n(lbs.)\nNo. of\nTablets\n2 - 4\n0.5\n5 - 7\n1.0\n8 - 12\n1.5\n13 - 18\n2.0\n19 - 25\n2.5\nfor Medium Dogs\n(26 - 60 lbs.)\nBody Wt.\n(lbs.)\nNo. of\nTablets\n26 - 30\n1.0\n31 - 44\n1.5\n45 - 60\n2.0\nfor Large Dogs\n(45 lbs. and greater)\nBody Wt.\n(lbs.)\nNo. of\nTablets\n45 - 60\n1.0\n61 - 90\n1.5\n91 - 120\n2.0\nFASTING IS NEITHER NECESSARY NOR RECOMMENDED.","FDA application 141-007",{"id":272,"dose_text":273,"species":11,"administration_route":236,"limitation":11,"source_label":274},10823,"Quad Dewormer Chewable Tablets for Dogs may be given directly in the mouth or offered in a small amount of food. You should weigh your dog to make sure you are using the right size and number of tablets. Administer to dogs and puppies* only as follows:\nQuad Dewormer Chewable Tablets for Dogs Dosage Charts\n*NOT FOR USE IN PUPPIES LESS THAN 3 WEEKS OF AGE OR DOGS WEIGHING LESS THAN 2 LBS.\nfor Puppies and Small Dogs*\n(2 - 25 lbs.)\nBody Wt.\n(lbs.)\nNo. of\nTablets\n2 - 4\n0.5\n5 - 7\n1.0\n8 - 12\n1.5\n13 - 18\n2.0\n19 - 25\n2.5\nfor Medium Dogs\n(26 - 60 lbs.)\nBody Wt.\n(lbs.)\nNo. of\nTablets\n26 - 30\n1.0\n31 - 44\n1.5\n45 - 60\n2.0\nfor Large Dogs\n(45 lbs. and greater)\nBody Wt.\n(lbs.)\nNo. of\nTablets\n45 - 60\n1.0\n61 - 90\n1.5\n91 - 120\n2.0\nFASTING IS NEITHER NECESSARY NOR RECOMMENDED.","Elanco™ Quad Dewormer (praziquantel\u002Fpyrantel pamoate\u002Ffebantel)",{"id":276,"dose_text":277,"species":11,"administration_route":236,"limitation":11,"source_label":278},10824,"Each flavored chewable contains 30 mg of pyrantel pamoate and 30 mg of praziquantel. The dose for each drug is 2.27 mg per pound of body weight (5 mg\u002Fkg). Please refer to the following dosing table for help finding the right dose for your dog.\n7 Way De-Wormer Flavored Chewables Dosing Table\n• You should weigh your dog to make sure you are giving the right dose.\n• 7 Way De-Wormer Flavored Chewables are palatable if offered by hand. If your dog does not voluntarily eat the chewable, you can hide the chewable in a small amount of food or place it in the back of the dog's mouth for forced swallowing.\n• Make sure that the dog eats the complete dose.\n• Watch your dog for a few minutes after dosing to make sure the chewable is not rejected.","7 Way De-Wormer (pyrantel pamoate\u002Fpraziquantel) Flavored Chewables",{"id":280,"dose_text":281,"species":11,"administration_route":236,"limitation":11,"source_label":282},10825,"Each flavored chewable contains 114 mg of pyrantel pamoate and 114 mg of praziquantel. The dose for each drug is 2.27 mg per pound of body weight (5 mg\u002Fkg). Please refer to the following dosing table for help finding the right dose for your dog.\nVIRBANTEL Flavored Chewables Dosing Table\nYou should weigh your dog to make sure you are giving the right dose.\nVIRBANTEL Flavored Chewables are palatable if offered by hand. If your dog does not voluntarily eat the chewable, you can hide the chewable in a small amount of food or place it in the back of the dog's mouth for forced swallowing.\nMake sure that the dog eats the complete dose.\nWatch your dog for a few minutes after dosing to make sure the chewable is not rejected.","Virbantel® Flavored Chewables",{"id":284,"dose_text":285,"species":11,"administration_route":236,"limitation":11,"source_label":286},10826,"1) While holding plunger, turn the knurled ring on the plunger ¼ turn to the left and slide it so the side nearest the barrel is at the prescribed weight marking, aligning the arrow on the plunger with the notch on the ring, as shown in the pictogram.\n2) Lock the ring in place by making ¼ turn to the right. Ensure it is locked (it should no longer slide).\n3) Make sure that the horse's mouth contains no feed.\n4) Remove the cover from the tip of the syringe.\n5) Insert the syringe tip into the horse's mouth at the space between the teeth.\n6) Depress the plunger as far as it will go, depositing paste on the back of the tongue.\n7) Immediately raise the horse's head for a few seconds after dosing.","ZIMECTERIN® GOLD(ivermectin 1.55% \u002F praziquantel 7.75%) Paste",{"id":288,"dose_text":289,"species":11,"administration_route":236,"limitation":11,"source_label":290},10827,"Droncit (praziquantel tablets) 34 Canine Cestocide may be administered directly per os or crumbled and mixed with the feed. The recommended dosage of praziquantel varies according to body weight. Smaller animals require a relatively larger dosage because of their higher metabolic rate. The optimum dose for each individual animal will be achieved by utilizing the following dosage schedule:\nDogs and Puppies*\n* Not intended for use in puppies less than 4 weeks of age.\n5 lbs. and under\n½ tablet\n6-10 lbs.\n1 tablet\n11-15 lbs.\n1 ½ tablets\n16-30 lbs.\n2 tablets\n31-45 lbs.\n3 tablets\n46-60 lbs.\n4 tablets\nOver 60 lbs.\n5 tablets max","Elanco DroncitTM (praziquantel tablets) 34 Canine Cestocide",{"id":292,"dose_text":293,"species":11,"administration_route":236,"limitation":11,"source_label":294},10828,"DOSAGE AND ADMINISTRATION:\nTo ensure proper dosage, weigh the cat prior to treatment.\nAdminister as a single oral dose according to the following table.\nDOSAGE TABLE:\nBody Weight: 2–3 lbs\nNumber of Tablets: 0.5 tablet\nBody Weight: 4–8 lbs\nNumber of Tablets: 1.0 tablet\nBody Weight: 9–12 lbs\nNumber of Tablets: 1.5 tablets\nBody Weight: 13–16 lbs\nNumber of Tablets: 2.0 tablets\nNot for use in kittens less than 2 months of age or weighing less\nthan 2 lbs.\nDIRECTIONS FOR USE:\nTablets may be given directly by mouth or offered in a small amount\nof food.\nDo not withhold food from the cat prior to or after treatment.","OZIPCO Fenbendazole CAT DEWORMER",{"id":296,"dose_text":297,"species":11,"administration_route":236,"limitation":11,"source_label":298},10829,"QUEST PLUS Gel is specially formulated as a palatable gel which is easily administered to horses and ponies. QUEST PLUS Gel is packaged in ready-to-use SURE-DIAL® syringes. The syringe is calibrated in 50-pound increments, up to 1500 pounds. This enables the administration of the recommended dose level by choosing a setting consistent with the animal’s weight.\nDo not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineff ective treatment, and encourage the development of parasite resistance.","QUEST® PLUS GEL (moxidectin\u002Fpraziquantel)",{"id":300,"dose_text":301,"species":11,"administration_route":236,"limitation":11,"source_label":302},10830,"Droncit (praziquantel tablets) 23 Feline Cestocide may be administered directly per os or crumbled and mixed with the feed. The recommended dosage of praziquantel varies according to body weight. Smaller animals require a relatively larger dosage because of their higher metabolic rate. The optimum dose for each individual animal will be achieved by utilizing the following dosage schedule:\nCats and Kittens*\n*Not intended for use in kittens less than 6 weeks of age.\n4 pounds and under\n½ tablet\n5-11 pounds\n1 tablet\nOver 11 pounds\n1 ½ tablets","Elanco DroncitTM (praziquantel tablets) 23 Feline Cestocide",{"id":304,"dose_text":305,"species":11,"administration_route":231,"limitation":11,"source_label":306},10831,"Directions for Use:\nFor best results, remove activated carbon or filter cartridge from filter and continue aeration.\nFor each 20 gallons (75 L) of water add 1 scoop (1 tsp.).\nFor larger systems, for each 240 gallons (908 L) of water add 12 scoops (4 Tbsp.). or for each 960 gallons (3,634 L) of water add one cup.\nRepeat dose after 48 hours.\nWait another 48 hours then change 25% of the aquarium water and add API BIO CHEM ZORB, fresh activated carbon or replace filter cartridge.\nWill not discolor water.\nSafe for use with live plants","Drug Label",{"id":308,"dose_text":309,"species":11,"administration_route":236,"limitation":11,"source_label":286},10832,"This syringe contains sufficient paste to treat one 1250 lb horse at the recommended dose rate of 91 mcg ivermectin per lb (200 mcg\u002Fkg) body weight and 454 mcg praziquantel per lb (1 mg\u002Fkg) body weight. Each weight marking on the syringe plunger delivers enough paste to treat 250 lb body weight.\nDo not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the development of parasite resistance.",{"id":311,"dose_text":312,"species":11,"administration_route":231,"limitation":11,"source_label":306},10833,"Directions for Use:\nFor best results, remove activated carbon or filter cartridge from filter and continue aeration.\nFor each 10 gallons (38 L) of water, empty one packet directly into aquarium.\nRepeat dose after 48 hours.\nWait another 48 hours then change 25% of the aquarium water and add fresh activated carbon or replace filter cartridge.\nThis package treats up to 100 gallons.\nTwo doses required for full course of treatment.\nWill not discolor water\nSafe for use with live plants.",{"id":314,"dose_text":315,"species":11,"administration_route":236,"limitation":11,"source_label":316},10834,"Tapeworm Dewormer (praziquantel tablets) may be given directly in the mouth or crumbled and mixed with the food. Administer to dogs and puppies* only as follows:\n*Not intended for use in puppies less than 4 weeks of age.\nBody Weight (lbs)\nNo. of Tablets\n5 lbs. and under\n½ tablet\n6-10 lbs.\n1 tablet\n11-15 lbs.\n1½ tablets\n16-30 lbs.\n2 tablets\n31-45 lbs.\n3 tablets\n46-60 lbs.\n4 tablets\nOver 60 lbs.\n5 tablets maximum\nFASTING IS NEITHER NECESSARY NOR RECOMMENDED.","Elanco™ Tapeworm Dewormer (praziquantel tablets) for dogs",{"id":318,"dose_text":319,"species":11,"administration_route":261,"limitation":11,"source_label":262},10835,"Droncit (praziquantel) Injectable Cestocide may be administered by either the subcutaneous or intramuscular route to dogs and cats. The intramuscular route may be preferred in dogs due to a brief period of pain that occasionally follows subcutaneous administration.\nAnaphylactoid reactions were not observed in clinical trials. However, as with any drug an anaphylactoid reaction can occur with this product and should be treated symptomatically if it occurs.",{"id":321,"dose_text":322,"species":11,"administration_route":236,"limitation":11,"source_label":323},10836,"To assure proper dosage, weigh the cat prior to treatment. Select the number of whole or partial tablets needed for the cat from the following table.\n*NOT FOR USE IN KITTENS LESS THAN TWO MONTHS OF AGE OR WEIGHING LESS THAN 2 LBS.\nBody Weight*\n(lbs.)\nNumber of\nTablets\n2 – 3\n½\n4 – 8\n1\n9 – 12\n1 ½\n13 – 16\n2\nDrontal Tablets may be given directly by mouth or offered in a small amount of food. Do not withhold food from the cat prior to or after treatment.","Elanco™ Drontal™(praziquantel\u002Fpyrantel pamoate)Tablets Broad Spectrum Dewormer For Cats And Kittens",{"id":325,"dose_text":326,"species":11,"administration_route":236,"limitation":11,"source_label":327},10837,"DIRECTIONS:\nAdminister orally or mix with food as a single dose.\nRepeat monthly if necessary, or as directed by your veterinarian.\nFasting is neither necessary nor recommended.\nDOSAGE CHART:\nWeight: 3 lbs\nDose: 0.25 mL\nWeight: 6 lbs\nDose: 0.50 mL\nWeight: 9 lbs\nDose: 0.75 mL\nWeight: 12 lbs\nDose: 1.00 mL\nWeight: 15 lbs\nDose: 1.25 mL\nOver 15 lbs, use a combination to obtain the appropriate dose.\nNot intended for use in kittens less than 5 weeks of age.","OZIPCO FenbendazoleCAT Dewormer Liquid",{"id":329,"dose_text":330,"species":11,"administration_route":236,"limitation":11,"source_label":331},10838,"Administer the product once as specified in the following table or as suggested by your veterinarian.\nBody Weight (lbs.)\nNO. of tablets\n2-3\n0.5\n4-8\n1.0\n9-12\n1.5\n13-16\n2.0\nGive orally or mixed with food. Offer a dosage as a single treatment or as recommended.\nDewormer tablets may be given directly by mouth or offered in a small amount of food. Do not withhold food from the cat prior to or after treatment.","Broad Spectrum Cat & Dog Dewormer (praziquantel \u002F pyrantel pamoate) tablets",{"id":333,"dose_text":334,"species":11,"administration_route":236,"limitation":11,"source_label":335},10839,"Usage and Dosage\nShake well before use.\nMay be given directly by mouth or mixed with a small amount of food.\nGive once daily for 2 consecutive days, or as directed by your veterinarian.\nDosage Table:\nWeight 3-\u003C6 lb: 0.25 mL\nWeight 6-\u003C9 lb: 0.50 mL\nWeight 9-\u003C12 lb: 0.75 mL\nWeight 12-\u003C15 lb: 1 mL\nOver 15 lbs: use combination to obtain dose.\nAge Restriction:\nNot for puppies \u003C4 weeks or kittens \u003C6 weeks.","VRETTSIO Praziquantel 5% Oral Suspension",{"id":337,"dose_text":338,"species":11,"administration_route":236,"limitation":11,"source_label":339},10840,"Tapeworm Dewormer (praziquantel tablets) may be given directly in the mouth or crumbled and mixed with the food. Administer to cats and kittens* only as follows:\n*Not intended for use in kittens less than 6 weeks of age.\nBody Weight (lbs)\nNo. of Tablets\n4 pounds and under\n½ tablet\n5-11 pounds\n1 tablet\nOver 11 pounds\n1 ½ tablets\nFASTING IS NEITHER NECESSARY NOR RECOMMENDED.","Elanco™ Tapeworm Dewormer (praziquantel tablets) for cats",{"id":341,"dose_text":342,"species":11,"administration_route":236,"limitation":11,"source_label":343},10841,"• Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism.\n• Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness.\n• 7 Way De-Wormer Flavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested.","FDA application 141-261",{"id":345,"dose_text":346,"species":11,"administration_route":236,"limitation":11,"source_label":347},10842,"One syringe contains sufficient paste to treat one 1250 lb horse at the recommended dose rate (0.2 mg\u002Fkg) body weight. Do not underdose. Ensure each animal receives a complete dose based on a current body weight. Underdosing may result in ineffective treatment, and encourage the development of parasite resistance.","Vetr Prazimectin (14.03% Praziquantel, 1.87% ivermectin oral paste)",{"id":349,"dose_text":350,"species":11,"administration_route":236,"limitation":11,"source_label":351},10843,"To assure proper dosage, weigh the cat prior to treatment. Select the number of whole or partial tablets needed for the cat from the following table.\nTablets may be given directly by mouth or offered in a small amount of food. Do not withhold food from the cat prior to or after treatment.","FDA application 141-008",{"id":353,"dose_text":354,"species":11,"administration_route":355,"limitation":11,"source_label":356},10844,"Add one packet PraziCleanse per 20 gallons. After 5 days, perform a 25% water change and repeat treatment. Discontinue use of skimmer, UV sterilizers, carbon and other adsorptive resins during treatment. NOTE: Not safe for use in marine systems with tube worms or feather dusters.","EXTRACORPOREAL","PraziCleanse",{"id":358,"dose_text":359,"species":11,"administration_route":236,"limitation":11,"source_label":360},10845,"Give orally or mixed with food ONCE a day for 2 days, Repeat Monthly if needed.\nDosage Chart:\nCat Weight\nDose\n3 lbs\n0.25 ml\n6 lbs\n0.50 ml\n9 lbs\n0.75 ml\n12 lbs\n1.0 mls\n15 lbs\n1.25 mls\nOver 15lbs\nuse combination to obtain dose.\nShake well before use.","GiarCidia Prazi",{"id":362,"dose_text":363,"species":11,"administration_route":236,"limitation":11,"source_label":364},10846,"Solely for use under the guidance of your veterinarian. Please consult your veterinarian for dosing size, duration and readministration schedule.","Vetr Praziquantel, 5% Oral Suspension",[366,370,372,376,380,382,385,387,391,394,396,398,400,405,408,412,416,419,421,423,425,427,429,431,433,435,437,439,441,444,447,449,453,456,459,462,464,466,468,471,474,477,481,483,486,490,493,497,500,503,507,510,513,516,520,523],{"id":367,"strength_text":368,"dosage_form":369,"proprietary_name":46,"species":38,"source_label":46},9502,"Each milliliter contains 56.8 milligrams of praziquantel.","Liquid (Solution)",{"id":371,"strength_text":368,"dosage_form":369,"proprietary_name":46,"species":76,"source_label":46},9503,{"id":373,"strength_text":374,"dosage_form":375,"proprietary_name":106,"species":76,"source_label":106},9504,"Each chewable tablet contains either:\n68 mcg ivermectin, 1,134 mg fenbendazole, and 57 mg praziquantel; or\n27 mcg ivermectin, 454 mg fenbendazole, and 23 mg praziquantel.","Chewable Tablets",{"id":377,"strength_text":378,"dosage_form":379,"proprietary_name":112,"species":110,"source_label":112},9505,"Each chewable tablet contains: 30 mg praziquantel and 30 mg pyrantel pamoate (For Small Dogs and Puppies) or 114 mg praziquantel and 114 mg pyrantel pamoate (For Medium and Large Dogs).","Tablet (Chewable)",{"id":381,"strength_text":378,"dosage_form":379,"proprietary_name":112,"species":115,"source_label":112},9506,{"id":383,"strength_text":378,"dosage_form":375,"proprietary_name":384,"species":115,"source_label":384},9507,"Worm X Plus®",{"id":386,"strength_text":378,"dosage_form":375,"proprietary_name":384,"species":110,"source_label":384},9508,{"id":388,"strength_text":389,"dosage_form":390,"proprietary_name":56,"species":38,"source_label":56},9509,"Each mL contains 21.4 mg emodepside and 85.7 mg praziquantel","Liquid",{"id":392,"strength_text":393,"dosage_form":379,"proprietary_name":121,"species":119,"source_label":121},9510,"Each chewable tablet contains:\n(1) 34 micrograms (mcg) ivermectin, 28.5 milligrams (mg) pyrantel pamoate, and 28.5 mg praziquantel;\n(2) 68 mcg ivermectin, 57 mg pyrantel pamoate, and 57 mg praziquantel;\n(3) 136 mcg ivermectin, 114 mg pyrantel pamoate, and 114 mg praziquantel; or\n(4) 272 mcg ivermectin, 228 mg pyrantel pamoate, and 228 mg praziquantel.",{"id":395,"strength_text":393,"dosage_form":379,"proprietary_name":121,"species":125,"source_label":121},9511,{"id":397,"strength_text":393,"dosage_form":379,"proprietary_name":121,"species":129,"source_label":121},9512,{"id":399,"strength_text":393,"dosage_form":379,"proprietary_name":121,"species":133,"source_label":121},9513,{"id":401,"strength_text":402,"dosage_form":403,"proprietary_name":404,"species":137,"source_label":404},9514,"Each milligram of paste contains 0.0155 milligram (1.55 percent) ivermectin and 0.0775 milligram (7.75 percent) praziquantel.","Paste","ZIMECTERIN® Gold Paste",{"id":406,"strength_text":407,"dosage_form":403,"proprietary_name":139,"species":137,"source_label":139},9515,"Each milligram of paste contains 0.0187 mg (1.87 percent) ivermectin and 0.1403 mg (14.03 percent) praziquantel.",{"id":409,"strength_text":410,"dosage_form":411,"proprietary_name":150,"species":148,"source_label":150},9516,"Each milliliter of gel contains 20 milligrams (2.0 percent) moxidectin and 125 milligrams (12.5 percent) praziquantel.","Gel",{"id":413,"strength_text":414,"dosage_form":415,"proprietary_name":91,"species":76,"source_label":91},9517,"Each dog tablet contains 34 milligrams of praziquantel; each cat tablet contains 23 milligrams of praziquantel.","Tablet",{"id":417,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":154,"source_label":156},9518,"Each tablet contains either:\n1) 22.7 milligrams praziquantel, 22.7 milligrams pyrantel base, and 113.4 milligrams febantel\n2) 68 milligrams praziquantel, 68 milligrams pyrantel base, and 340.2 milligrams febantel\nor\n3) 136 milligrams praziquantel, 136 milligrams pyrantel base, and 680.4 milligrams febantel",{"id":420,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":160,"source_label":156},9519,{"id":422,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":164,"source_label":156},9520,{"id":424,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":168,"source_label":156},9521,{"id":426,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":172,"source_label":156},9522,{"id":428,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":176,"source_label":156},9523,{"id":430,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":180,"source_label":156},9524,{"id":432,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":184,"source_label":156},9525,{"id":434,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":188,"source_label":156},9526,{"id":436,"strength_text":418,"dosage_form":415,"proprietary_name":156,"species":192,"source_label":156},9527,{"id":438,"strength_text":418,"dosage_form":415,"proprietary_name":197,"species":195,"source_label":197},9528,{"id":440,"strength_text":418,"dosage_form":415,"proprietary_name":197,"species":200,"source_label":197},9529,{"id":442,"strength_text":443,"dosage_form":415,"proprietary_name":206,"species":204,"source_label":206},9530,"Each tablet contains 18.2 mg praziquantel and 72.6 mg pyrantel base as pyrantel pamoate.",{"id":445,"strength_text":368,"dosage_form":369,"proprietary_name":446,"species":76,"source_label":446},9531,"Droncit™ 5.68% Injectible Solution",{"id":448,"strength_text":368,"dosage_form":369,"proprietary_name":446,"species":38,"source_label":446},9532,{"id":450,"strength_text":451,"dosage_form":415,"proprietary_name":452,"species":76,"source_label":452},9533,"Each dog tablet contains 34 milligrams of praziquantel","Droncit® Canine Cestocide Tablets",{"id":454,"strength_text":455,"dosage_form":415,"proprietary_name":68,"species":38,"source_label":68},9534,"Each cat tablet contains 23 milligrams of praziquantel.",{"id":457,"strength_text":451,"dosage_form":415,"proprietary_name":458,"species":76,"source_label":458},9535,"Praziquantel 34 (Rx)",{"id":460,"strength_text":461,"dosage_form":403,"proprietary_name":212,"species":210,"source_label":212},9536,"Each gram of paste contains 34 milligrams of febantel and 3.4 milligrams of praziquantel.",{"id":463,"strength_text":461,"dosage_form":403,"proprietary_name":212,"species":216,"source_label":212},9537,{"id":465,"strength_text":461,"dosage_form":403,"proprietary_name":212,"species":219,"source_label":212},9538,{"id":467,"strength_text":461,"dosage_form":403,"proprietary_name":212,"species":222,"source_label":212},9539,{"id":469,"strength_text":470,"dosage_form":375,"proprietary_name":227,"species":226,"source_label":227},9540,"Each chewable tablet contains:\n2.3 mg milbemycin oxime\u002F22.8 mg praziquantel\n5.75 mg milbemycin oxime\u002F57 mg praziquantel\n11.5 mg milbemycin oxime\u002F114 mg praziquantel\n23 mg milbemycin oxime\u002F228 mg praziquantel",{"id":472,"strength_text":473,"dosage_form":375,"proprietary_name":82,"species":76,"source_label":82},9541,"Each chewable tablet contains: 2.3 mg milbemycin oxime\u002F46 mg lufenuron\u002F22.8 mg praziquantel; 5.75 mg milbemycin oxime\u002F115 mg lufenuron\u002F57 mg praziquantel; 11.5 mg milbemycin oxime\u002F230 mg lufenuron\u002F114 mg praziquantel; 23.0 mg milbemycin oxime\u002F460 mg lufenuron\u002F228 mg praziquantel",{"id":475,"strength_text":476,"dosage_form":403,"proprietary_name":144,"species":137,"source_label":144},9542,"Each milligram of Duocare™ paste contains 0.0187 mg (1.87%) ivermectin and 0.2338 mg (23.38%) praziquantel. Each syringe contains 113.75 mg of ivermectin and 1421.5 mg of praziquantel.",{"id":478,"strength_text":479,"dosage_form":480,"proprietary_name":51,"species":38,"source_label":51},9543,"56.8 mg\u002FmL","Injectable Solution",{"id":482,"strength_text":479,"dosage_form":480,"proprietary_name":51,"species":76,"source_label":51},9544,{"id":484,"strength_text":485,"dosage_form":375,"proprietary_name":78,"species":76,"source_label":78},9545,"Each chewable tablet contains either: 1) 34 micrograms (mcg) ivermectin, 28.5 milligrams (mg) pyrantel pamoate, and 28.5 mg praziquantel; 2) 68 mcg ivermectin, 57 mg pyrantel pamoate, and 57 mg praziquantel; 3) 136 mcg ivermectin, 114 mg pyrantel pamoate, and 114 mg praziquantel; or 4) 272 mcg ivermectin, 228 mg pyrantel pamoate, and 228 mg praziquantel.",{"id":487,"strength_text":488,"dosage_form":489,"proprietary_name":62,"species":38,"source_label":62},9546,"Eprinomectin – 4 mg\u002FmL; Praziquantel – 83 mg\u002FmL","Transdermal Solution",{"id":491,"strength_text":492,"dosage_form":375,"proprietary_name":72,"species":76,"source_label":72},9547,"34 mg per tablet",{"id":494,"strength_text":495,"dosage_form":496,"proprietary_name":40,"species":38,"source_label":40},9548,"Each mL of topical solution contains 12 mg esafoxolaner, 4 mg eprinomectin, and 83 mg praziquantel.","Topical Solution",{"id":498,"strength_text":499,"dosage_form":375,"proprietary_name":102,"species":76,"source_label":102},9549,"56.25 mg lotilaner, 0.056 mg moxidectin, 14.25 mg praziquantel, and 14.25 mg pyrantel; 112.5 mg lotilaner, 0.113 mg moxidectin, 28.5 mg praziquantel, and 28.5 mg pyrantel; 225 mg lotilaner, 0.225 mg moxidectin, 57 mg praziquantel, and 57 mg pyrantel; 450 mg lotilaner, 0.45 mg moxidectin, 114 mg praziquantel, and 114 mg pyrantel; 900 mg lotilaner, 0.9 mg moxidectin, 228 mg praziquantel, and 228 mg pyrantel",{"id":501,"strength_text":502,"dosage_form":375,"proprietary_name":72,"species":38,"source_label":72},9550,"Each chewable tablet contains 23 mg praziquantel.",{"id":504,"strength_text":505,"dosage_form":375,"proprietary_name":506,"species":76,"source_label":506},9551,"Each chewable tablet contains: 56.25 mg lotilaner, 0.056 mg moxidectin, 14.25 mg praziquantel, and 14.25 mg pyrantel* 112.5 mg lotilaner, 0.113 mg moxidectin, 28.5 mg praziquantel, and 28.5 mg pyrantel* 225 mg lotilaner, 0.225 mg moxidectin, 57 mg praziquantel, and 57 mg pyrantel* 450 mg lotilaner, 0.45 mg moxidectin, 114 mg praziquantel, and 114 mg pyrantel* 900 mg lotilaner, 0.9 mg moxidectin, 228 mg praziquantel, and 228 mg pyrantel* *As pamoate salt","Credelio Quattro™-CA1",{"id":508,"strength_text":509,"dosage_form":11,"proprietary_name":11,"species":11,"source_label":356},9552,"190 mg \u002F 1 g",{"id":511,"strength_text":512,"dosage_form":11,"proprietary_name":11,"species":11,"source_label":266},9553,"10 mg \u002F 1 mL",{"id":514,"strength_text":515,"dosage_form":11,"proprietary_name":11,"species":11,"source_label":360},9554,"50 mg \u002F 1 mL",{"id":517,"strength_text":518,"dosage_form":11,"proprietary_name":11,"species":11,"source_label":519},9555,"56.8 mg \u002F 1 mL","Praziquantel (praziquantel) Injection INJECTABLE CESTOCIDE FOR DOGS AND CATS 56.8 mg\u002FmL Solution",{"id":521,"strength_text":522,"dosage_form":11,"proprietary_name":11,"species":11,"source_label":290},9556,"34 mg \u002F 1 1",{"id":524,"strength_text":525,"dosage_form":11,"proprietary_name":11,"species":11,"source_label":302},9557,"23 mg \u002F 1 1",[527,531,534,537,540,543,546,549,552,556,559,562,565,568,572,576,579,581,584,586,588,590,594,597,600,603,606,608,611,613,615,617,619,621,623,625,627,629,631,633,635,637,639,641,643,645,648,651,653,656,658,661,664,667,670,673,676,679,682,685,688,691,694,697,700,703,707,710,713,716,719,722,725,729,732,735,738,741,744,747,751,754,757,760,764,767,770,774,777,780,783,786,790,793,796,799,802,805,808,811,814,817,820,823,826,830,833,836,839,842,845,848,851,855,857,860,863,867,871,874,877,880,883,886,889,892,895,898,901,904,907,910,913,916,919,922],{"id":528,"kind":529,"statement":530,"species":38,"limitation":11,"source_label":40},15538,"indication","For the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (fourth stage larval and adult Toxocara cati), hookworm (fourth stage larval and adult Ancylostoma tubaeforme; adult Ancylostoma braziliense), and tapeworm (Dipylidium caninum) infections. Kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations and the treatment and control of Ixodes scapularis (black-legged tick) and Amblyomma americanum (lone star tick) infestations for one month in cats and kittens 8 weeks of age and older, and weighing 1.8 lbs or greater.",{"id":532,"kind":529,"statement":533,"species":38,"limitation":61,"source_label":62},15539,"For the prevention of heartworm disease caused by Dirofilaria immitis, and for the treatment and control of roundworms (adult and fourth stage larval Toxocara cati), hookworms (adult and fourth stage larval Ancylostoma tubaeforme; adult Ancylostoma braziliense), and tapeworms (adult Dipylidium caninum and Echinococcus multilocularis), in cats and kittens 7 weeks of age and older and 1.8 lbs or greater.",{"id":535,"kind":529,"statement":536,"species":38,"limitation":55,"source_label":56},15540,"For the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults).",{"id":538,"kind":529,"statement":539,"species":38,"limitation":45,"source_label":46},15541,"For removal of feline cestodes Dipylidium caninum and Taenia taeniaeformis.",{"id":541,"kind":529,"statement":542,"species":76,"limitation":11,"source_label":102},15542,"Credelio Quattro™ is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina), hookworm (fourth stage larvae, immature adult, and adult Ancylostoma caninum and adult Uncinaria stenocephala), and tapeworm (Dipylidium caninum, Taenia pisiformis, and Echinococcus granulosus) infections. Credelio Quattro™ kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Amblyomma Americanum (lone star tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), Rhipicephalus sanguineus (brown dog tick), and Haemaphysalis longicornis (longhorned tick)] for one month in dogs and puppies 8 weeks of age and older, and weighing 3.3 pounds or greater. Credelio Quattro™ is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.",{"id":544,"kind":529,"statement":545,"species":76,"limitation":61,"source_label":82},15543,"For the prevention of heartworm disease caused by Dirofilaria immitis; for the prevention and control of flea populations (Ctenocephalides felis); and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina), adult hookworm (Ancylostoma caninum), adult whipworm (Trichuris vulpis), and adult tapeworm (Dipylidium caninum,Taenia pisiformis, Echinococcus multilocularis and Echinococcus granulosus) infections in dogs and puppies two pounds of body weight or greater and six weeks of age and older.",{"id":547,"kind":529,"statement":548,"species":76,"limitation":77,"source_label":78},15544,"For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of roundworms (Toxocara canis, Toxascaris leonina), hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense), and tapeworms (Dipylidium caninum, Taenia pisiformis).",{"id":550,"kind":529,"statement":551,"species":76,"limitation":61,"source_label":106},15545,"For the treatment and control of adult Toxocara canis (roundworm), Ancylostoma caninum (hookworm), Trichuris vulpis (whipworm), and Dipylidium caninum (tapeworm), and for the prevention of heartworm disease caused by Dirofilaria immitis in adult dogs.",{"id":553,"kind":529,"statement":554,"species":76,"limitation":555,"source_label":452},15546,"For removal of the canine cestode Echinococcus granulosus, and for removal and control of the canine cestode Echinococcus multilocularis. For removal of canine cestodes Dipylidium caninum and Taenia pisiformis.","Administer directly by mouth or crumbled and in feed. Not intended for use in puppies less than 4 weeks of age.",{"id":557,"kind":529,"statement":558,"species":76,"limitation":555,"source_label":458},15547,"For removal of canine cestodes Dipylidium caninum and Taenia pisiformis. For removal of the canine cestode Echinococcus granulosus, and for removal and control of the canine cestode Echinococcus multilocularis.",{"id":560,"kind":529,"statement":561,"species":76,"limitation":11,"source_label":506},15548,"For the treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in dogs and puppies 8 weeks of age and older, and weighing 3.3 pounds or greater.",{"id":563,"kind":529,"statement":564,"species":76,"limitation":11,"source_label":72},15549,"For the removal of the following canine cestodes: Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus and for the removal and control of Echinococcus multilocularis.",{"id":566,"kind":529,"statement":567,"species":76,"limitation":86,"source_label":46},15550,"For removal of canine cestodes: Dipylidium caninum, Taenia pisiformis, and Echinococcus granulosus, and removal and control of canine cestode Echinococcus multilocularis.",{"id":569,"kind":529,"statement":570,"species":76,"limitation":61,"source_label":571},15551,"For removal of the canine cestode Echinococcus granulosus, and for removal and control of the canine cestode Echinococcus multilocularis.","Praziquantel Tablets (Rx)",{"id":573,"kind":529,"statement":574,"species":76,"limitation":90,"source_label":575},15552,"For removal of canine cestodes Dipylidium caninum and Taenia pisiformis.","Tapeworm Dewormer for Dogs (OTC)",{"id":577,"kind":529,"statement":578,"species":110,"limitation":111,"source_label":112},15553,"For the treatment and control of roundworms (Toxocara canis and Toxascaris leonine), hookworms (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala), and tapeworms (Dipylidium caninum and Taenia pisiformis) in dogs and puppies.",{"id":580,"kind":529,"statement":578,"species":115,"limitation":111,"source_label":112},15554,{"id":582,"kind":529,"statement":583,"species":119,"limitation":120,"source_label":121},15555,"Prevents canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for 1 month (30 days) after infection and for the treatment and control of roundworm (Toxocara canis, Toxascaris leonine), hookworm (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense) and tapeworm (Dipylidium caninum, Taenia pisiformis) infections.",{"id":585,"kind":529,"statement":583,"species":125,"limitation":120,"source_label":121},15556,{"id":587,"kind":529,"statement":583,"species":129,"limitation":120,"source_label":121},15557,{"id":589,"kind":529,"statement":583,"species":133,"limitation":120,"source_label":121},15558,{"id":591,"kind":529,"statement":592,"species":137,"limitation":593,"source_label":404},15559,"For treatment and control of the following parasites in horses: tapeworms--Anoplocephala perfoliata; large strongyles (adults)-- Strongylus vulgaris (also early forms in blood vessels), S. edentates (also tissue stages), S. equinus, Triodontophorus species including T. brevicauda and T. serratus, and Craterostomum acuticaudatum; small strongyles (adults, including those resistant to some benzimidazole class compounds)--Coronocyclus species including C. coronatus, C. labiatus, and C. labratus, Cyathostomum species including C. catinatum and C. pateratum, Cylicocyclus species including C. insigne, C. leptostomum, C. nassatus, and C. brevicapsulatus, Cylicodontophorus species, Cylicostephanus species including C. calicatus, C. goldi, C. longibursatus, and C. minutus, and Petrovinema poculatum; small strongyles-fourth-stage larvae; pinworms (adults and fourth stage larvae)--Oxyuris equi; Ascarids (adults and third- and fourth-stage larvae)--Parascaris equorum; hairworms (adults)--Trichostrongylus axei; large-mouth stomach worms (adults)--Habronema muscae; bots (oral and gastric stages)--Gasterophilus species including G. intestinalis and G. nasalis; lungworms (adults and fourth-stage larvae)--Dictyocaulus arnfieldi; intestinal threadworms (adults)--Strongyloides westeri; summer sores caused by Habronema and Draschia species cutaneous third-stage larvae; Dermatitis caused by neck threadworm microfilariae, Onchocerca species.","For oral use only. Do not use in horses intended for human consumption.\nThis product should not be used in other animal species as severe adverse reactions, including fatalities\nin dogs, may result.",{"id":595,"kind":529,"statement":596,"species":137,"limitation":143,"source_label":144},15560,"For the treatment and control of the following parasites in horses over 5 months of age:\nTapeworms Anoplocephala perfoliata; Large Strongyles (adults) - Strongylus vulgaris (also early forms in blood vessels), S. edentatus (also tissue stages), S. equinus, Triodontophorus spp. including T. brevicauda and T. serratus, and Craterostomum acuticaudatum; Small Strongyles (adults, including those resistant to some benzimidazole class compounds) - Coronocyclus spp. including C. coronatus, C. labiatus and C. labratus; Cyathostomum spp. including C. catinatum and C. pateratum; Cylicocyclus spp. including C. insigne, C. leptostomum, C. nassatus and C. brevicapsulatus; Cylicodontophorus spp. Cylicostephanus spp. including C. calicatus, C. goldi, C. longibursatus and C. minutus, and Petrovinema poculatum; Small Strongyles - Fourth-stage larvae; Pinworms (adults and fourth-stage larvae)- Oxyuris equi; Ascarids (adults and third- and fourth-stage larvae) - Parascaris equorum; Hairworms (adults) - Trichostrongylus axei; Large-mouth Stomach Worms (adults) - Habronema muscae; Bots (oral and gastric stages) - Gasterophilus spp. including G. intestinalis and G. nasalis; Lungworms (adults and fourth-stage larvae) - Dictyocaulus arnfieldi; Intestinal Threadworms (adults) - Strongyloides westeri; Summer Sores caused by Habronema and Draschia spp. cutaneous third-stage larvae; Dermatitis caused by neck threadworm microfilariae, Onchocerca sp.",{"id":598,"kind":529,"statement":599,"species":137,"limitation":138,"source_label":139},15561,"For treatment and control of the following parasites in horses: Tapeworms--Anoplocephala perfoliata; Large Strongyles (adults)--Strongylus vulgaris (also early forms in blood vessels), S.edentatus (also tissue stages), S. equinus, Triodontophorus spp.; Small Strongyles (adults, including those resistant to some benzimidazole class compounds)--Cyathostomum species, Cylicocyclus species, Cylicostephanus species, Cylicodontophorus species; Small Strongyles--fourth-stage larvae; Pinworms (adults and fourth-stage larvae)--Oxyuris equi; Ascarids (adults and third- and fourth-stage larvae)--Parascaris equorum; Hairworms (adults)--Trichostrongylus axei; Large-mouth Stomach Worms (adults)--Habronema muscae; Bots (oral and gastric stages)--Gasterophilus species; Lungworms (adults and fourth-stage larvae)--Dictyocaulus arnfieldi; Intestinal Threadworms (adults)--Strongyloides westeri; Summer Sores caused by Habronema and Draschia spp. cutaneous third-stage larvae; Dermatitis caused by neck threadworm microfilariae, Onchocerca species.",{"id":601,"kind":529,"statement":602,"species":148,"limitation":149,"source_label":150},15562,"For the treatment and control of large strongyles: Strongylus vulgaris (adults and L4\u002FL5 arterial stages), S. edentatus (adult and tissue stages), Triodontophorus brevicauda (adults), and T. serratus (adults); small strongyles (adults): (Cyathostomum species, including C. catinatum and C. pateratum; Cylicocyclus species, including C. insigne, C. leptostomum, C. nassatus and Cylicocyclus radiatus; Cylicostephanus species, including C. calicatus, C. goldi, C. longibursatus, and C. minutus; Coronocyclus species, including C. coronatus, C. labiatus, and C. labratus; Gyalocephalus capitatus; and Petrovinema poculatus; small strongyles: undifferentiated luminal larvae; encysted cyathostomes (late L3 and L4 mucosal cyathostome larvae); ascarids: Parascaris equorum (adults and L4 larval stages); pinworms: Oxyuris equi (adults and L4 larval stages); hairworms: Trichostrongylus axei (adults); large-mouth stomach worms: Habronema muscae (adults); horse stomach bots: Gasterophilus intestinalis (2nd and 3rd instars) and G. nasalis (3rd instars); and tapeworms: Anoplocephala perfoliata (adults). One dose also suppresses strongyle egg production for 84 days.",{"id":604,"kind":529,"statement":605,"species":154,"limitation":155,"source_label":156},15563,"For the removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus); hookworms (Ancylostoma caninum, Uncinaria stenocephala); ascarids (Toxocara canis, Toxascaris leonina); and whipworms (Trichuris vulpis) and for removal and control of tapeworm (Echinococcus multilocularis).",{"id":607,"kind":529,"statement":605,"species":160,"limitation":155,"source_label":156},15564,{"id":609,"kind":529,"statement":610,"species":164,"limitation":196,"source_label":197},15565,"Quad Dewormer (praziquantel\u002Fpyrantel pamoate\u002Ffebrantel) Chewable Tablets for Dogs will remove the common tapeworms, Dipylidium caninum and Taenia pisiformis, remove common hookworms, Ancylostoma caninum and Uncinaria stenocephala, remove common roundworms, Toxocara canis and Toxascaris leonina, and remove whipworms, Trichuris vulpis in dogs.",{"id":612,"kind":529,"statement":605,"species":164,"limitation":155,"source_label":156},15566,{"id":614,"kind":529,"statement":610,"species":168,"limitation":196,"source_label":197},15567,{"id":616,"kind":529,"statement":605,"species":168,"limitation":155,"source_label":156},15568,{"id":618,"kind":529,"statement":610,"species":172,"limitation":196,"source_label":197},15569,{"id":620,"kind":529,"statement":605,"species":172,"limitation":155,"source_label":156},15570,{"id":622,"kind":529,"statement":610,"species":176,"limitation":196,"source_label":197},15571,{"id":624,"kind":529,"statement":605,"species":176,"limitation":155,"source_label":156},15572,{"id":626,"kind":529,"statement":610,"species":180,"limitation":196,"source_label":197},15573,{"id":628,"kind":529,"statement":605,"species":180,"limitation":155,"source_label":156},15574,{"id":630,"kind":529,"statement":610,"species":184,"limitation":196,"source_label":197},15575,{"id":632,"kind":529,"statement":605,"species":184,"limitation":155,"source_label":156},15576,{"id":634,"kind":529,"statement":610,"species":188,"limitation":196,"source_label":197},15577,{"id":636,"kind":529,"statement":605,"species":188,"limitation":155,"source_label":156},15578,{"id":638,"kind":529,"statement":610,"species":192,"limitation":196,"source_label":197},15579,{"id":640,"kind":529,"statement":605,"species":192,"limitation":155,"source_label":156},15580,{"id":642,"kind":529,"statement":610,"species":195,"limitation":196,"source_label":197},15581,{"id":644,"kind":529,"statement":610,"species":200,"limitation":196,"source_label":197},15582,{"id":646,"kind":529,"statement":647,"species":204,"limitation":205,"source_label":206},15583,"For removal of the common parasites of cats and kittens including tapeworms (Dipylidium caninum, Taenia taeniaeformis), hookworms (Ancylostoma tubaeforme), and large roundworms (Toxocara cati).",{"id":649,"kind":529,"statement":650,"species":210,"limitation":211,"source_label":212},15584,"For removal of hookworms (Ancylostoma caninum and Uncinaria stenocephala), whipworms (Trichuris vulpis), ascarids (Toxocara canis and Toxascaris leonina), and tapeworms (Dipylidium caninum and Taenia pisiformis).",{"id":652,"kind":529,"statement":650,"species":216,"limitation":211,"source_label":212},15585,{"id":654,"kind":529,"statement":655,"species":219,"limitation":211,"source_label":212},15586,"For removal of hookworms (Ancylostoma tubaeforme), ascarids (Toxocara cati) and tapeworms (Dipylidium caninum and Taenia taeniaeformis).",{"id":657,"kind":529,"statement":655,"species":222,"limitation":211,"source_label":212},15587,{"id":659,"kind":529,"statement":660,"species":226,"limitation":61,"source_label":227},15588,"For the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina), adult hookworm (Ancylostoma caninum), adult whipworm (Trichuris vulpis), and adult tapeworm (Taenia pisiformis, Echinococcus multilocularis, and Echinococcus granulosus) and Dipylidium caninum infections in dogs and puppies two pounds of body weight or greater and six weeks of age and older.",{"id":662,"kind":529,"statement":663,"species":11,"limitation":11,"source_label":323},15589,"Drontal (praziquantel\u002Fpyrantel pamoate) tablets will remove Tapeworms (Dipylidium caninum, Taenia taeniaeformis), Hookworms (Ancylostoma tubaeforme), and Large Roundworms (Toxocara cati) in cats and kittens.\nThe presence of tapeworms is indicated by the observance of tapeworm segments passed in the cat's feces. Tapeworm segments are white, pinkish-white or yellow-white in color and are similar in size and shape to flattened grains of rice. The segments are most frequently observed lying on a freshly passed stool. Segments may also be found on the hair around the anus of the animal or on the animal's bedding. Cats become infected with tapeworms after eating fleas or small mammals (rabbits, mice) which may be infected with tapeworm larvae.\nHookworms are small whitish or reddish-brown worms less than one inch in length that live in the intestinal tract and feed on blood. Cats can become infected with hookworms by swallowing infected larvae while grooming or when larvae from the environment burrow through the skin. Cats infected with hookworms may have poor physical condition, dull haircoat, and reduced body weight and diarrhea, sometimes with the presence of dark blood.\nLarge roundworms are white or yellow-white strands 2-7 inches in length (similar in size and color to smooth strings of spaghetti) that may be observed in the cat's vomit or feces. Cats become infected with large roundworms by swallowing infective eggs, particularly while grooming, or by ingestion of mice that may be infected with larval stages.\nLarge roundworms and hookworms pass eggs in the feces of the cat that can only be observed with the aid of a microscope.\nThe presence of these parasites should be confirmed through identification of parasite eggs in the feces.\nConsult your veterinarian for assistance in the diagnosis, treatment and control of parasites.\nLarge roundworms and hookworms may be observed in the feces of the cat a day or so after the cat has been treated with Drontal Tablets. The majority of tapeworms, however, are digested and are not found in the feces after treatment.",{"id":665,"kind":529,"statement":666,"species":11,"limitation":11,"source_label":306},15590,"Diagnostic Chart\nGill and Skin Flukes:\nVery common fish parasites. Can be found on the gills, scales or skin. Not visible without the aid of magnification. Symptoms may include: darkening of skin, clamped fins, excess mucous. Fish may also swim erratically or become emaciated.\nHole-in-the-Head Disease:\nSymptoms include pitting and erosion of skin and muscle tissue around the face and side of body. Many infected fish exhibit poor appetite, weight loss and nervousness.\nWasting Disease:\nFish parasites transmitted fromn fish to fish cause emaciation, anemia and lethargy.Tissue damage leading to subsequent ulceration of the gastrointestinal tract. Excess mucus and white stringy feces are often produced as a result of parasitic invasion.\nSwollen Abdomen:\nFish infected with tapeworms (cestodes), often have an extended or swollen abdomen. Internal area of attachment results in damaged tissue. Fish normally show signs of reduction ingrowth and general malaise.\nTreatment Tips\nQuarantine aquarium. Remove any dead fish immediately. Do not remove or add any live fish to the infected aquarium. Parasitic infections are highly contagious and can spread to other aquariums by nets, algae scrapers and wet hands.\nTo speed up the life cycle of parasites and shorten treatment period, raise water temperature to 82 F (28 C).\nTo aid osmoreregulation and ease stress of infected fish, add 1 tablespoon of API AQUARIUM SALT for each 5 gallons (19 L) of aquarium water, or 1 -1\u002F4 cup for each 100 gallons (378 L).\nThis medication may be used in combination with API antibacterial medications, including API MELAFIX, to help prevent scondary bacterial infection.",{"id":668,"kind":529,"statement":669,"species":11,"limitation":11,"source_label":286},15591,"Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. ZIMECTERIN® GOLD (ivermectin\u002Fpraziquantel) Paste provides effective treatment and control of the following parasites in horses. Tapeworms – Anoplocephala perfoliata, Large Strongyles (adults) – Strongylus vulgaris (also early forms in blood vessels), S. edentatus (also tissue stages), S. equinus, Triodontophorus spp. including T. brevicauda and T. serratus and Craterostomum acuticaudatum; Small Strongyles (adults, including those resistant to some benzimidazole class compounds) – Coronocyclus spp. including C. coronatus, C. labiatus and C. labratus, Cyathostomum spp. including C. catinatum and C. pateratum, Cylicocyclus spp. including C. insigne, C. leptostomum, C. nassatus, and C. brevicapsulatus, Cylicodontophorus spp., Cylicostephanus spp., including C. calicatus, C. goldi, C. longibursatus and C. minutus, and Petrovinema poculatum; Small Strongyles – Fourth-stage larvae; Pinworms (adults and fourth-stage larvae) – Oxyuris equi; Ascarids (adults and third- and fourth-stage larvae) – Parascaris equorum; Hairworms (adults) – Trichostrongylus axei; Large-mouth Stomach Worms (adults) – Habronema muscae; Bots (oral and gastric stages) – Gasterophilus spp. including G. intestinalis and G. nasalis; Lungworms (adults and fourth-stage larvae) – Dictyocaulus arnfieldi; Intestinal Threadworms (adults) – Strongyloides westeri; Summer Sores caused by Habronema and Draschia spp. cutaneous third-stage larvae; Dermatitis caused by neck threadworm microfilariae, Onchocerca sp.",{"id":671,"kind":529,"statement":672,"species":11,"limitation":11,"source_label":298},15592,"QUEST PLUS Gel (moxidectin\u002Fpraziquantel) when administered at the recommended dose level of 0.4 mg moxidectin\u002Fkg and 2.5 mg praziquantel\u002Fkg (2.2 lb) body weight is effective in the treatment and control of the following stages of gastrointestinal parasites in horses and ponies:\nLarge Strongyles:\nStrongylus\nvulgaris – (adults and L4\u002FL5 arterial stages)\nStrongylus edentatus – (adults and tissue stages)\nTriodontophorus brevicauda – (adults)\nTriodontophorus serratus – (adults)\nSmall Strongyles(adults):\nCyathostomumspp., including\nCyathostomum catinatum\nCyathostomum pateratum\nCylicostephanus spp., including\nCylicostephanus\ncalicatus\nCylicostephanus\ngoldi\nCylicostephanus\nlongibursatus\nCylicostephanus\nminutus\nCylicocyclus spp., including\nCylicocyclus insigne\nCylicocyclus leptostomum\nCylicocyclus nassatus\nCylicocyclus radiatus\nCoronocyclusspp., including\nCoronocyclus coronatus\nCoronocyclus labiatus\nCoronocyclus labratus\nGyalocephalus capitatus\nPetrovinema\npoculatus\nSmall Strongyles:\nUndifferentiated lumenal larvae\nEncysted cyathostomes:\nLate L3 and L4 mucosal cyathostome larvae\nAscarids:\nParascaris\nequorum – (adults and L4 larval stages)\nPinworms:\nOxyuris equi – (adults and L4 larval stages)\nHairworms:\nTrichostrongylus axei– (adults)\nLarge-mouth stomach worms:\nHabronema muscae– (adults)\nHorse stomach bots:\nGasterophilus intestinalis– (2nd and 3rd instars)\nGasterophilus nasalis– (3rd instars)\nTapeworms:\nAnoplocephala\nperfoliata – (adults)\nOne administration of the recommended dose rate of QUEST PLUS Gel also suppresses strongyle egg production through 84 days.",{"id":674,"kind":529,"statement":675,"species":11,"limitation":11,"source_label":237},15593,"Credelio Quattro is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina), hookworm (fourth stage larvae, immature adult, and adult Ancylostoma caninum and adult Uncinaria stenocephala), and tapeworm (Dipylidium caninum, Taenia pisiformis, and Echinococcus granulosus) infections. Credelio Quattro kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) and the treatment and control of tick infestations [Amblyomma americanum (lone star tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), Rhipicephalus sanguineus (brown dog tick), and Haemaphysalis longicornis (longhorned tick)] for one month in dogs and puppies 8 weeks of age and older, and weighing 3.3 pounds or greater. Credelio Quattro is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.\nCredelio Quattro-CA1 is indicated for the treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) in dogs and puppies 8 weeks of age and older, and weighing 3.3 pounds or greater.",{"id":677,"kind":529,"statement":678,"species":11,"limitation":11,"source_label":245},15594,"Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism.\nEQUIMAX (ivermectin\u002Fpraziquantel) Oral Paste is indicated for the treatment and control of the following parasites:\nTapeworms\nAnoplocephala perfoliata\nLarge Strongyles (adults)\nStrongylus vulgaris (also early forms in blood vessels)\nS. edentatus (also tissue stages)\nS. equinus\nTriodontophorus spp.\nSmall Strongyles (adults, including those resistant to some benzimidazole class compounds)\nCyathostomum spp.\nCylicocyclus spp.\nCylicostephanus spp.\nCylicodontophorus spp.\nSmall Strongyles (fourth-stage larvae)\nPinworms (adults and fourth-stage larvae)\nOxyuris equi\nAscarids (adults and third- and fourth-stage larvae)\nParascaris equorum\nHairworms (adults)\nTrichostrongylus axei\nLarge-mouth Stomach Worms (adults)\nHabronema muscae\nBots (oral and gastric stages)\nGasterophilus spp.\nLungworms (adults and fourth-stage larvae)\nDictyocaulus arnfieldi\nIntestinal Threadworms (adults)\nStrongyloides westeri\nSummer Sores caused by Habronema and Draschia spp. cutaneous third-stage larvae\nDermatitis caused by Neck Threadworm microfilariae, Onchocerca sp.",{"id":680,"kind":529,"statement":681,"species":11,"limitation":11,"source_label":306},15595,"Diagnostic Chart\nGill and Skin Flukes:\nVery common fish parasite. Can be found on the gills, scales or skin. Not visible without the aid of magnification. Symptoms may include: darkening of skin, clamped fins, excess mucous. Fish may also swim erratically or become emaciated.\nHole-in-the-Head Disease:\nSymptoms include pitting and erosion of skin and muscle tissue around the face and side of body. Many infected fish exhibit poor appetite, weight loss and nervousness.\nWasting Disease:\nFish parasites transmitted from fish to fish cause emaciation, anemia and lethargy. Tissue damage leading to subsequent ulceration of the gastrointestinal tract. Excess mucus and white stringy feces are often produced as a result of parasitic invasion.\nSwollen Abdomen:\nFish infected with tapeworms (cestodes), often have an extended or swollen abdomen. Internal areas of attachment results in damaged tissue. Fish normally show signs of reduction in growth and general malaise.",{"id":683,"kind":529,"statement":684,"species":11,"limitation":11,"source_label":282},15596,"Each flavored chewable contains 30 mg of pyrantel pamoate and 30 mg of praziquantel. The dose for each drug is 2.27 mg per pound of body weight (5 mg\u002Fkg). Please refer to the following dosing table for help finding the right dose for your dog.\nVIRBANTEL® Flavored Chewables Dosing Table\nYou should weigh your dog to make sure you are giving the right dose.\nVIRBANTEL Flavored Chewables are palatable if offered by hand. If your dog does not voluntarily eat the chewable, you can hide the chewable in a small amount of food or place it in the back of the dog's mouth for forced swallowing.\nMake sure that the dog eats the complete dose.\nWatch your dog for a few minutes after dosing to make sure the chewable is not rejected.",{"id":686,"kind":529,"statement":687,"species":11,"limitation":11,"source_label":343},15597,"Each flavored chewable contains 114 mg of pyrantel pamoate and 114 mg of praziquantel. The dose for each drug is 2.27 mg per pound of body weight (5 mg\u002Fkg). Please refer to the following dosing table for help finding the right dose for your dog.\nYou should weigh your dog to make sure you are giving the right dose.\n7 Way De-Wormer Flavored Chewables are palatable if offered by hand. If your dog does not voluntarily eat the chewable, you can hide the chewable in a small amount of food or place in the back of the dog's mouth for forced swallowing.\nMake sure that the dog eats the complete dose.\nWatch your dog for a few minutes after dosing to make sure the chewable is not rejected.",{"id":689,"kind":529,"statement":690,"species":11,"limitation":11,"source_label":232},15598,"NexGard® COMBO is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (fourth stage larval and adult Toxocara cati), hookworm (fourth stage larval and adult Ancylostoma tubaeforme; adult Ancylostoma\nbraziliense), and tapeworm (Dipylidium caninum) infections. NexGard® COMBO kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations and the treatment and control of Ixodes scapularis (black-legged tick) and Amblyomma americanum (lone star tick) infestations for one month in cats and kittens 8 weeks of age and older, and weighing 1.8 lbs or greater.",{"id":692,"kind":529,"statement":693,"species":11,"limitation":11,"source_label":356},15599,"Common Symptoms of Parasitic Diseases Treated\nSkin Flukes: Extra mucous, visible spots or worms, flashing, scratching or rubbing on rocks\nWasting Disease: Clamped fins, weight loss, lethargy, deformity\nGill Flukes: Discolored, swollen gills, rapid breathing, gasping at surface\nPraziCleanse is a safe anti-parasitic treatment to control unwanted parasites. Our easy-to-use packet dosing system is effective against skin and gill flukes, tapeworms, flatworms, and turbellarians. Works in both fresh and saltwater systems without affecting biological filtration when used as directed. PraziCleanse is safe for use with most invertebrates.",{"id":695,"kind":529,"statement":696,"species":11,"limitation":11,"source_label":253},15600,"Indications: SENTINEL SPECTRUM Chews are indicated for the prevention of heartworm disease caused by Dirofilaria immitis; for the prevention and control of flea populations (Ctenocephalides felis); and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina), adult hookworm (Ancylostoma caninum), adult whipworm (Trichuris vulpis), and adult tapeworm (Dipylidium caninum, Taenia pisiformis, Echinococcus multilocularis and Echinococcus granulosus) infections in dogs and puppies two pounds of body weight or greater and six weeks of age and older.",{"id":698,"kind":529,"statement":699,"species":11,"limitation":11,"source_label":257},15601,"INTERCEPTOR PLUS is indicated for the prevention of heartworm disease caused by Dirofilaria immitis; and for the treatment and control of adult roundworm (Toxocara canis, Toxascaris leonina), adult hookworm (Ancylostoma caninum), adult whipworm (Trichuris vulpis), and adult tapeworm (Taenia pisiformis, Echinococcus multilocularis, Echinococcus granulosus, and Dipylidium caninum) infections in dogs and puppies two pounds of body weight or greater and six weeks of age and older.",{"id":701,"kind":529,"statement":702,"species":11,"limitation":11,"source_label":266},15602,"Treatment against skin worms (Gyrodactylus), trematodes (Dactylogyrus) and tapeworms (Cestodes) in ornamental fish of the orders Cypriniformes, Perch, Catfish and live bearers in fresh water and marine water. Trematode infestation results in an increased respiratory rate. Ornamental fish with tapeworms frequently lose weight rapidly despite normal eating habits. Skin worm infestation will cause fish to attempt to rid themselves of the parasites by scraping.",{"id":704,"kind":529,"statement":705,"species":11,"limitation":11,"source_label":706},15603,"Drontal Plus (praziquantel\u002Fpyrantel pamoate\u002Ffebantel) Taste Tabs Broad Spectrum Chewable Anthelmintic Tablets are indicated for removal of Tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus, and removal and control of Echinococcus multilocularis) and for removal of Hookworms (Ancylostoma caninum, Uncinaria stenocephala), Ascarids (Toxocara canis, Toxascaris leonina), and Whipworms (Trichuris vulpis) in dogs.","Elanco DrontalTM Plus (praziquantel\u002Fpyrantel pamoate\u002Ffebantel) Taste TabsTM Broad Spectrum Chewable Anthelmintic Tablets for Dogs",{"id":708,"kind":529,"statement":709,"species":11,"limitation":11,"source_label":270},15604,"Drontal Plus (praziquantel\u002Fpyrantel pamoate\u002F febantel) Broad Spectrum Anthelmintic Tablets are indicated for removal of Tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus, and removal and control of Echincoccus multilocularis). For removal of Hookworms (Ancylostoma caninum, Uncinaria stenocephala), Ascarids (Toxocara canis, Toxascaris leonina), and Whipworms (Trichuris vulpis) in dogs.",{"id":711,"kind":529,"statement":712,"species":11,"limitation":11,"source_label":241},15605,"For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of roundworms (Toxocara canis, Toxascaris leonina), hookworms (Ancylostoma\ncaninum, Uncinaria stenocephala, Ancylostoma braziliense), and tapeworms (Dipylidium caninum, Taenia pisiformis).",{"id":714,"kind":529,"statement":715,"species":11,"limitation":11,"source_label":249},15606,"PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults) in cats.",{"id":717,"kind":529,"statement":718,"species":11,"limitation":11,"source_label":270},15607,"Dog Worm Tabs (praziquantel\u002F pyrantel pamoate\u002F febantel) Chewable Tablets for Dogs will remove the common tapeworms, Dipylidium caninum and Taenia pisiformis, remove common hookworms, Ancylostoma caninum and Uncinaria stenocephala, remove common roundworms, Toxocara canis and Toxascaris leonina, and remove whipworms, Trichuris vulpis in dogs.",{"id":720,"kind":529,"statement":721,"species":11,"limitation":11,"source_label":262},15608,"Droncit (praziquantel) Injectable Cestocide is indicated for the removal of the following canine and\u002For feline cestodes. Dogs: Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus and for the removal and control of Echinococcus multilocularis. Cats: Taenia taeniaeformis and Dipylidium caninum.",{"id":723,"kind":529,"statement":724,"species":11,"limitation":11,"source_label":290},15609,"Droncit (praziquantel tablets) 34 Canine Cestocide are indicated for the removal of the following canine cestodes: Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus and for the removal and control of Echinococcus multilocularis.",{"id":726,"kind":529,"statement":727,"species":11,"limitation":11,"source_label":728},15610,"For the treatment and control of:\n• Roundworms (Toxocara canis, Toxascaris leonina)\n• Hookworms (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala)\n• Tapeworms (Dipylidium caninum, Taenia pisiformis)","Triple Wormer® (pyrantel pamoate\u002Fpraziquantel) Flavored Chewables",{"id":730,"kind":529,"statement":731,"species":11,"limitation":11,"source_label":331},15611,"For removal of the common parasites of cats, kittens and dogs including Tapeworms (Dipylidium caninum, Taenia taeniaeformis), Hookworms (Ancylostoma tubaeforme) and Large Roundworms (Toxocara cati).",{"id":733,"kind":529,"statement":734,"species":11,"limitation":11,"source_label":728},15612,"• Tapeworms (Dipylidium caninum, Taenia pisiformis)\n• Roundworms (Toxocara canis, Toxascaris leonina)\n• Hookworms (Ancylostoma caninum, Ancylostoma braziliense, and Uncinaria stenocephala)",{"id":736,"kind":529,"statement":737,"species":11,"limitation":11,"source_label":302},15613,"Droncit (praziquantel tablets) 23 Feline Cestocide are indicated for the removal of the following feline cestodes: Dipylidium caninum and Taenia taeniaeformis.",{"id":739,"kind":529,"statement":740,"species":11,"limitation":11,"source_label":294},15614,"Praziquantel\u002FPyrantel Pamoate Tablets are a broad-spectrum dewormer\nfor the removal and control of tapeworms, roundworms, and hookworms\nin cats and kittens.",{"id":742,"kind":529,"statement":743,"species":11,"limitation":11,"source_label":339},15615,"TAPEWORM DEWORMER (praziquantel tablets) will remove the common tapeworms, Dipylidium caninum and Taenia taeniaeformis, from cats and kittens.",{"id":745,"kind":529,"statement":746,"species":11,"limitation":11,"source_label":335},15616,"For the treatment and removal of adult tapeworm infections in cats.",{"id":748,"kind":749,"statement":750,"species":11,"limitation":11,"source_label":706},15617,"contraindication","DO NOT USE IN PREGNANT ANIMALS. Dogs treated with elevated levels (6 consecutive days with 3 times the labeled dosage rate) of the combination of febantel and praziquantel in early pregnancy demonstrated an increased incidence of abortion and fetal abnormalities.8 The effects of Drontal Plus Anthelmintic Tablets on pregnant animals have not been determined.\nThere are no known contraindications against the use of praziquantel or pyrantel pamoate in dogs.",{"id":752,"kind":749,"statement":753,"species":11,"limitation":11,"source_label":266},15618,"No known contraindications or side effects. Should you notice side effects in your ornamental fish, please inform your vet or pharmacist.",{"id":755,"kind":749,"statement":756,"species":11,"limitation":11,"source_label":253},15619,"Contraindications: There are no known contraindications to the use of SENTINEL SPECTRUM Chews.",{"id":758,"kind":749,"statement":759,"species":11,"limitation":11,"source_label":237},15620,"There are no known contraindications for the use of Credelio Quattro\u002FCredelio Quattro-CA1.",{"id":761,"kind":749,"statement":762,"species":11,"limitation":11,"source_label":763},15621,"There are no known contraindications to the use of praziquantel in dogs.","Praziquantel Tablets 34 mg Canine Cestocide",{"id":765,"kind":749,"statement":766,"species":11,"limitation":11,"source_label":257},15622,"There are no known contraindications to the use of INTERCEPTOR PLUS.",{"id":768,"kind":749,"statement":769,"species":11,"limitation":11,"source_label":232},15623,"There are no known contraindications for the use of NexGard® COMBO.",{"id":771,"kind":772,"statement":773,"species":11,"limitation":11,"source_label":249},15624,"warning","Not for human use. Keep out of reach of children.\nTo prevent accidental ingestion of the product, children should not come in contact with the application site for twenty-four (24) hours while the product is being absorbed. Pregnant women, or women who may become pregnant, should avoid direct contact with, or wear disposable gloves when applying, this product. Studies performed in rats and rabbits suggest that emodepside may interfere with fetal development in those species.\nPROFENDER Topical Solution may be irritating to skin and eyes. Reactions such as facial, tongue and hand swelling have been reported in humans in rare instances. Avoid contact with the application area while it is wet and wash hands thoroughly with soap and warm water after handling. People with known hypersensitivity to butylhydroxyanisole, emodepside or praziquantel should administer the product with caution. If the product accidentally gets into eyes, flush thoroughly with water. May be harmful if swallowed. In case of accidental ingestion or if skin or eye irritation occurs, call a poison control center or physician for treatment advice.\nThe Safety Data Sheet (SDS) provides additional occupational safety information. For product questions, to report adverse reactions, or for a copy of the Safety Data Sheet (SDS), call Elanco Product & Veterinary Support at 888-545-5973.",{"id":775,"kind":772,"statement":776,"species":11,"limitation":11,"source_label":286},15625,"Parasite resistance may develop to any dewormer, and has been reported for most classes of dewormers.\nTreatment with a dewormer used in conjunction with parasite management practices appropriate to the geographic area and the animal(s) to be treated may slow the development of parasite resistance.\nFecal examinations or other diagnostic tests and parasite management history should be used to determine if the product is appropriate for the herd\u002Fflock, prior to the use of any dewormer. Following the use of any dewormer, effectiveness of treatment should be monitored (for example, with the use of a fecal egg count reduction test or another appropriate method).\nA decrease in a drug's effectiveness over time as calculated by fecal egg count reduction tests may indicate the development of resistance to the dewormer administered. Your parasite management plan should be adjusted accordingly based on regular monitoring.",{"id":778,"kind":772,"statement":779,"species":11,"limitation":11,"source_label":232},15626,"Not for human use. Keep this and all drugs out of sight and reach of children.\nAvoid direct contact with application site for 4 hours or until visibly dry.\nThis product may act as a mild to moderate eye irritant.\nKeep product in the original packaging until use. Wash hands after product administration. If the product accidentally gets into the eyes, rinse thoroughly with water. If wearing contact lenses, flush the eyes first with water and then remove the lenses and continue to flush thoroughly with water. In case of accidental ingestion, or if skin or eye irritation occurs, contact a poison control center or physician for treatment advice.",{"id":781,"kind":772,"statement":782,"species":11,"limitation":11,"source_label":728},15627,"Keep this and all medication out of the reach of children. To obtain product information, including a Safety Data Sheet (SDS), call 1-800-821-5570.\nWhen Using This Product:\n• Consult your veterinarian for assistance in the diagnosis, treatment,\nand control of parasitism.\n• Do not de-worm a dog or puppy that is sick. Consult a veterinarian for diagnosis of the illness.\n• Triple Wormer\nFlavored Chewables are safe for use in puppies 12 weeks or older and adult dogs. Safety in breeding dogs and pregnant bitches has not been tested.",{"id":784,"kind":772,"statement":785,"species":11,"limitation":11,"source_label":241},15628,"For use in dogs only. Keep this and all drugs out of reach of children and pets. In safety studies\nwith ivermectin\u002Fpyrantel pamoate\u002Fpraziquantel tablets, testicular hypoplasia was observed in some\ndogs receiving 3 and 5 times the maximum recommended dose monthly for 6 months (see Animal\nSafety).\nIn case of ingestion by humans, clients should be advised to contact a physician immediately.\nPhysicians may contact a Poison Control Center for advice concerning cases of ingestion by humans.",{"id":787,"kind":772,"statement":788,"species":11,"limitation":11,"source_label":789},15629,"Isolated incident of either salivation or diarrhea have been reported following treatment, but were considered non-significant. If these signs are observed and they persist, consult your veterinarian.\nQuestions? For product questions, to report side effects, or for a copy of the Safety Data Sheet (SDS), call Durvet, Inc. at 1-800-821-5570.\nFor additional information about reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or http:\u002F\u002Fwww.fda.gov\u002Freportanimalae.","FDA application 111-798",{"id":791,"kind":772,"statement":792,"species":11,"limitation":11,"source_label":286},15630,"Do not use in horses intended for human consumption.\nNot for use in humans. Keep this and all drugs out of reach of children.\nRefrain from smoking and eating when handling. Wash hands after use. Avoid contact with eyes. The Safety Data Sheet (SDS) contains more detailed occupational safety information. To report adverse reactions in users, to obtain more information, or to obtain a SDS, contact Boehringer Ingelheim Animal Health USA Inc. at 1-888-637-4251.",{"id":794,"kind":772,"statement":795,"species":11,"limitation":11,"source_label":335},15631,"Adverse Reactions:\nWhen used as directed, this product is generally well tolerated, and adverse reactions are rare.\nPrecautions:\n1. Administer according to the animal's body weight. Do not exceed the recommended dosage.\n2. Mild soft stools or temporary lethargy may occur after deworming. If vomiting or diarrhea persists, consult your veterinarian immediately.\n3. Keep out of the reach of children.",{"id":797,"kind":772,"statement":798,"species":11,"limitation":11,"source_label":306},15632,"KEEP OUT OF THE REACH OF CHILDREN.\nFor aquarium use only.\nNot for human consumption or for the treatment of fish intended for human consumption.\nAvoid contact with skin and eyes.\nMay cause irritation.\n! WARNING:\nThis product can expose you to chemicals including Metronidazole, which is known to the State of California to cause cancer.\nFor more information go to www.P65Warnings.ca.gov.",{"id":800,"kind":772,"statement":801,"species":11,"limitation":11,"source_label":245},15633,"Not for use in humans. Keep this and all drugs out of the reach of children. Refrain from eating or smoking when handling. Wash hands after use. Avoid contact with eyes. The Safety Data Sheet (SDS) contains more detailed occupational safety information. To report adverse reactions in users, to obtain more information, or to obtain a SDS, contact Bimeda Inc. at 1-888-524-6332.",{"id":803,"kind":772,"statement":804,"species":11,"limitation":11,"source_label":323},15634,"KEEP OUT OF REACH OF CHILDREN.\nConsult your veterinarian before administering to sick or pregnant animals.\nQuestions\u002FComments?\nFor product questions or to report side effects, contact Elanco US Inc. at 1-888-545-5973.\nFor additional information about reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or http:\u002F\u002Fwww.fda.gov\u002Freportanimalae",{"id":806,"kind":772,"statement":807,"species":11,"limitation":11,"source_label":298},15635,"Not for use in humans. Keep this and all drugs out of the reach of children. Do not ingest. If swallowed, induce vomiting. Wash hands and contaminated skin with soap and water. If accidental contact with eyes occurs, flush repeatedly with water. If irritation or any other symptom attributable to exposure to this product persists, consult your physician.",{"id":809,"kind":772,"statement":810,"species":11,"limitation":11,"source_label":237},15636,"Not for use in humans. Keep this and all drugs out of reach of children. Wash hands after handling. If accidentally ingested, seek medical attention immediately.\nKeep Credelio Quattro\u002FCredelio Quattro-CA1 in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.",{"id":812,"kind":772,"statement":813,"species":11,"limitation":11,"source_label":763},15637,"Keep out of the reach of children. Not for human use. For customer service or to obtain product information, including Safety Data Sheet, call 1-833-571-1525.\nKeep Praziquantel Tablets in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose.",{"id":815,"kind":772,"statement":816,"species":11,"limitation":11,"source_label":266},15638,"- dactymor is unsuitable for invertebrates. Snails, mussels, shrimps, etc. must be excluded from the treatment.\n- For ornamental fish of the orders Cypriniformes, perch, catfish and live bearers. Do not use on creatures which are used to obtain food.\n- Do not use after the expiry date.",{"id":818,"kind":772,"statement":819,"species":11,"limitation":11,"source_label":298},15639,"Extreme caution should be used when administering the product to foals, young and miniature horses, as overdosage may result in serious adverse reactions. Do not use in sick, debilitated, or underweight animals. Do not use in horses intended for human consumption.",{"id":821,"kind":772,"statement":822,"species":11,"limitation":11,"source_label":294},15640,"WARNINGS:\nKeep out of reach of children.\nCAUTIONS:\nDo not use in kittens less than 8 weeks of age or weighing less\nthan 2 lbs.\nUse with caution in sick or debilitated animals.\nConsult your veterinarian before administering to sick or pregnant\nanimals.",{"id":824,"kind":772,"statement":825,"species":11,"limitation":11,"source_label":327},15641,"SIDE EFFECTS:\nOccasional salivation, vomiting, diarrhea, reduced appetite or listlessness has been reported following treatment.\nThese effects are usually mild and temporary.\nIf any of these signs appear and persist, contact your veterinarian.",{"id":827,"kind":772,"statement":828,"species":11,"limitation":11,"source_label":829},15642,"For animal use only. Keep out of reach of children.\nConsult a veterinarian before use on sick or pregnant animals.\nNot for use in kittens less than 2 months of age or weighing less than 2 lbs.","LFHYM Broad Spectrum Cat Dewormer (praziquantel\u002Fpyrantel pamoate) tablets",{"id":831,"kind":772,"statement":832,"species":11,"limitation":11,"source_label":331},15643,"*NOT FOR USE IN PUPPIES LESS THAN 2 WEEKS OF AGE OR KITTENS LESS THAN 6 WEEKS OF AGE.\nCAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.",{"id":834,"kind":772,"statement":835,"species":11,"limitation":11,"source_label":356},15644,"THIS PRODUCT IS INTENDED FOR THE EXCLUSIVE USE WITH ORNAMENTAL ORGANISMS INDICATED AND IS NOT INTENDED FOR USE WITH OTHER ANIMALS, HUMANS, OR FISH FOR HUMAN CONSUMPTION",{"id":837,"kind":772,"statement":838,"species":11,"limitation":11,"source_label":343},15645,"Keep this and all medication out of the reach of children. To obtain product information, including a Safety Data Sheet (SDS), call call +1 5165860254.",{"id":840,"kind":772,"statement":841,"species":11,"limitation":11,"source_label":347},15646,"Not safe or approved for human use. May be used in horses of all ages including mares at any stage of pregnancy. KEEP OUT OF REACH OF CHILDREN.",{"id":843,"kind":772,"statement":844,"species":11,"limitation":11,"source_label":364},15647,"Shake well before use. Solely for use under the guadance of your veterinarian. Follow dosing instructions from your veterinarian.",{"id":846,"kind":772,"statement":847,"species":11,"limitation":11,"source_label":253},15648,"Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.",{"id":849,"kind":772,"statement":850,"species":11,"limitation":11,"source_label":253},15649,"Warnings: Not for use in humans. Keep this and all drugs out of the reach of children.",{"id":852,"kind":772,"statement":853,"species":11,"limitation":11,"source_label":854},15650,"Keep out of the reach of children. Not for human use.","Praziquantel Tablets 23 mg Feline Cestocide",{"id":856,"kind":772,"statement":143,"species":11,"limitation":11,"source_label":245},15651,{"id":858,"kind":772,"statement":859,"species":11,"limitation":11,"source_label":274},15652,"KEEP OUT OF REACH OF CHILDREN.\nUSE DIRECTIONS",{"id":861,"kind":772,"statement":862,"species":11,"limitation":11,"source_label":270},15653,"KEEP OUT OF REACH OF CHILDREN.",{"id":864,"kind":865,"statement":866,"species":11,"limitation":11,"source_label":237},15654,"adverse_reaction","In a field safety and effectiveness study, Credelio Quattro was administered to dogs for the prevention of heartworm disease. The study included a total of 372 dogs treated once monthly for up to 11 treatments (191 treated with Credelio Quattro and 181 treated with an active control). Over the 330-day study period, all observations of potential adverse reactions were recorded.\nAdverse reactions seen during the field study are summarized in the table below.\nDogs with Adverse Reactions in the Field Study\n*Four dogs administered Credelio Quattro and five dogs administered the active control had bloody diarrhea.\nClinical Sign\nCredelio Quattro\nN=191\nNumber (Percentage)\nActive Control\nN=181\nNumber (Percentage)\nDiarrhea, with or without blood*\n21 (11%)\n15 (8.3%)\nVomiting\n18 (9.4%)\n8 (4.4%)\nLethargy\n12 (6.3%)\n1 (0.6%)\nAnorexia\n11 (5.8%)\n5 (2.8%)\nDermatitis\n10 (5.2%)\n8 (4.4%)\nWeight Loss\n6 (3.1%)\n3 (1.7%)\nPruritus (itching)\n3 (1.6%)\n1 (0.6%)\nAlopecia (hair loss)\n2 (1.0%)\n4 (2.2%)\nSeizure\n1 (0.5%)\n4 (2.2%)\nAtaxia\n1 (0.5%)\n1 (0.6%)\nNystagmus\n1 (0.5%)\n0 (0.0%)\nAnisocoria\n1 (0.5%)\n1 (0.6%)\nOne geriatric dog receiving Credelio Quattro experienced two episodes of vomiting, ataxia, and nystagmus, 11 days apart, with the first episode occurring two days after the eighth dose. The dog recovered within 24 hours after the first episode and 1 hour after the second episode and completed the study. One dog receiving Credelio Quattro was observed by the investigator to have anisocoria during scheduled physical examinations one month after the ninth dose and one month after the eleventh dose.\nIn a second U.S. field safety and effectiveness study, Credelio Quattro was administered to 103 dogs with hookworms. Adverse reactions in dogs treated with Credelio Quattro included gastrointestinal signs (diarrhea, emesis) and lethargy.\nIn a U.S. field study, 165 dogs received a combination of lotilaner, moxidectin, and praziquantel, three of the active ingredients at the same doses as in Credelio Quattro, monthly for up to 11 months. Two dogs with no history of seizures experienced seizures during the study. One of the dogs developed cluster seizures and was removed from the study. Ataxia was also observed in one other dog three days after the first dose.\nIn a U.S. field study, one dog administered lotilaner alone, a component of Credelio Quattro, was observed with intermittent head tremors within 1.5 hours of administration of vaccines, an ear cleaning performed by the owner, and its first dose of lotilaner. The head tremors resolved within 24 hours without treatment. The owner elected to withdraw the dog from the study.\nIn an Australian field study, one dog with a history of seizures experienced seizure activity (tremors and glazed eyes) six days after receiving lotilaner alone. The dog recovered without treatment and completed the study. In a U.S. field study, two dogs with a history of seizures received lotilaner alone and experienced no seizures throughout the study.",{"id":868,"kind":865,"statement":869,"species":11,"limitation":11,"source_label":870},15655,"Field study: In a controlled, double-masked field safety study, owners administered PROFENDER Topical Solution to 606 cats. Adverse reactions reported by the cat owners included licking\u002Fexcessive grooming in 18 cats (3.0%), scratching treatment site in 15 cats (2.5%), salivation in 10 cats (1.7%), lethargy in 10 cats (1.7%), alopecia in 8 cats (1.3%), agitation\u002Fnervousness in 7 cats (1.2%), vomiting in 6 cats (1.0%), diarrhea in 3 cats (0.5%), eye irritation in 3 cats (0.5%), respiratory irritation in 1 cat (0.2%) and shaking\u002Ftremors in 1 cat (0.2%). All adverse reactions were self-limiting.\nLaboratory effectiveness studies: One cat died 10 days after receiving PROFENDER Topical Solution. The necropsy showed chronic active cholangiohepatitis. While the use of the drug did not appear to be the direct cause of death, treatment with the drug cannot be ruled out as a contributing factor (See PRECAUTIONS\n). One cat treated with a vehicle placebo (formulation minus the active ingredients) showed salivation, gagging, lethargy and a swollen tongue.\nForeign Market Experience: The following adverse events were reported voluntarily during post-approval use of the product in foreign markets: application site reaction (hair loss, dermatitis, pyoderma, edema, and erythema), salivation, pruritus, lethargy, vomiting, diarrhea, dehydration, ataxia, loss of appetite, facial swelling, rear leg paresis, seizures, hyperesthesia, twitching, and death.\nPost-Approval Experience: The following adverse events are based on post-approval adverse drug experience reporting. Not all adverse events are reported to FDA CVM. It is not always possible to reliably estimate the adverse event frequency or establish a causal relationship to product exposure using this data. The following adverse events are listed in decreasing order of reporting frequency in cats: Application site reaction (hair loss, dermatitis, pyoderma, edema, and erythema), hypersalivation, lethargy\u002Fdepression, vomiting, ataxia, anorexia, trembling\u002Ftwitching, diarrhea, mydriasis, fever, hyper-activity\u002Fnervousness. In some cases, death has been reported as an outcome of the adverse events listed. For a complete listing of the adverse reactions for Profender Topical Solution reported to the CVM see: http:\u002F\u002Fwww.fda.gov\u002FADEreports.\nThis listing includes Adverse Events reported to CVM for products, such as Profender, that contain the combined active ingredients emodepside and praziquantel. Listings by active ingredient may represent more than one brand name.\nCONTACT INFORMATION:\nFor product questions, to report adverse reactions, or for a copy of the Safety Data Sheet (SDS), call Elanco Product & Veterinary Support at 888-545-5973. For additional information about reporting adverse drug experiences for animal drugs, contact FDA at 1-888-FDA-VETS or http:\u002F\u002Fwww.fda.gov\u002Freportanimalae.","Topical Solution profender™ (emodepside\u002Fpraziquantel)",{"id":872,"kind":865,"statement":873,"species":11,"limitation":11,"source_label":232},15656,"In a field safety and effectiveness study, which included a total of 201 households and 380 treated cats (244 cats treated with NexGard® COMBO, 136 cats treated with an active control), the safety of NexGard® COMBO was evaluated over a 90-day period through in-clinic physical examinations or through reporting of abnormalities by the owner. The most frequently reported reactions in the NexGard® COMBO and active control groups are presented in the following table.\nAdverse Reactions by Treatment Group\nEVENT\nTreatment Group\nNEXGARD® COMBO\nActive Control\nn1\n% (n=244)\nn2\n% (n=136)\nVomiting\n16\n6.56\n8\n5.88\nApplication Site Hair Change\n9\n3.69\n0\n0.00\nAnorexia\n7\n2.87\n4\n2.94\nLethargy\n6\n2.46\n5\n3.68\nBacterial skin infection\n4\n1.64\n1\n0.74\nItching\n4\n1.64\n0\n0.00\nSneezing\n4\n1.64\n5\n3.68\nSkin Peeling\n3\n1.23\n2\n1.47\nDiarrhea\n3\n1.23\n3\n2.21\nEpiphora\n3\n1.23\n1\n0.74\nHypersalivation\n3\n1.23\n0\n0.00\nHyperthermia\n3\n1.23\n0\n0.00\nAlopecia\n2\n0.82\n0\n0.00\nDermal thickening\n2\n0.82\n0\n0.00\nEar Pruritus\n2\n0.82\n1\n0.74\nApplication Site Redness\n2\n0.82\n0\n0.00\nConjunctivitis\n1\n0.41\n1\n0.74\n1Number of cats treated with NexGard® COMBO with the identified abnormality.\n2Number of cats treated with Active Control with the identified abnormality.",{"id":875,"kind":865,"statement":876,"species":11,"limitation":11,"source_label":241},15657,"In a field study with IVERHART MAX Chew, self-limiting adverse reactions, including vomiting, diarrhea, lethargy, difficulty swallowing, excessive salivation, increased water consumption, and coughing were reported. Self-limiting adverse reactions, including lethargy, limpness, salivation, shaking, diarrhea, decreased appetite, licking lips, and belching were reported between 20 minutes and 72 hours following treatment in a field study with ivermectin\u002Fpyrantel pamoate\u002Fpraziquantel tablets.\nIn field studies with ivermectin\u002Fpyrantel\u002Fpraziquantel pamoate tablets, vomiting or diarrhea within 24 hours of dosing was rarely observed (1.1% of administered doses). The following adverse reactions have been reported in dogs following the use of ivermectin products: depression\u002Flethargy, vomiting,anorexia, diarrhea, mydriasis, ataxia, staggering, convulsions, and hypersalivation.\nTo report suspected adverse events, for technical assistance or to obtain a copy of the Safety Data Sheet (SDS), contact Virbac AH, Inc. at 1-800-338-3659 or us.virbac.com. For additional information about adverse drug experience reporting for animal drugs, contact the FDA at 1-888-FDA-VETS or www.fda.gov\u002Freportanimalae.",{"id":878,"kind":865,"statement":879,"species":11,"limitation":11,"source_label":519},15658,"Mild side effects were observed in 18 of 189 dogs (9.5%) and 8 of 85 cats (9.4%) administered Praziquantel Injection in field trials. For dogs the majority of these were described as brief pain responses following injections to larger dogs (weighing over 50 lbs.) Two dogs exhibited a brief period of mild vomiting and\u002For drowsy or staggering gait. The eight cats exhibited either diarrhea, weakness, vomition, salivation, sleepiness, burning on injection and\u002For a temporary lack of appetite. Local irritation or swelling at the site of subcutaneous injections have been reported for cats.\nCAUTION:\nFederal law restricts this drug to use by or on the order of a licensed veterinarian.",{"id":881,"kind":865,"statement":882,"species":11,"limitation":11,"source_label":253},15659,"Adverse Reactions: The following adverse reactions have been reported in dogs after administration of milbemycin oxime, lufenuron, or praziquantel: vomiting, depression\u002Flethargy, pruritus, urticaria, diarrhea, anorexia, skin congestion, ataxia, convulsions, salivation, and weakness.\nTo report suspected adverse drug events, contact Merck Animal Health at 1-800-224-5318. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or http:\u002F\u002Fwww.fda.gov\u002Freportanimalae.\nFor technical assistance, call Merck Animal Health at 1-800-224-5318.",{"id":884,"kind":865,"statement":885,"species":11,"limitation":11,"source_label":763},15660,"Seven instances (3.2%) of either vomiting, anorexia, lethargy or diarrhea were reported during the field trials in which 218 dogs were administered praziquantel tablets 34 canine cestocide. The investigators rated these as non-significant.\nContact Information: To report suspected adverse drug events, for technical assistance or to obtain a copy of the Safety Data Sheet, contact Felix Pharmaceuticals Private Limited at 1-833-571-1525. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or http:\u002F\u002Fwww.fda.gov\u002Freportanimalae",{"id":887,"kind":865,"statement":888,"species":11,"limitation":11,"source_label":257},15661,"The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, depression\u002Flethargy, ataxia, anorexia, convulsions, weakness, and salivation.\nContact Information\nFor product questions, to report adverse reactions, or to obtain a copy of the Safety Data Sheet (SDS), contact Elanco US, Inc. at 1-888-545-5973. For additional information about reporting adverse drug experiences for animal drugs, contact FDA at 1-888-FDA-VETS or http:\u002F\u002Fwww.fda.gov\u002Freportanimalae.",{"id":890,"kind":865,"statement":891,"species":11,"limitation":11,"source_label":351},15662,"Post-ApprovPost-Approval Experience: Although not all adverse reactions are reported, based on voluntary post-approval reporting, transient ataxia has been reported following the administration of Drontal Tablets for Cats and Kittens.al Experience: Although not all adverse reactions are reported, based on voluntary post-approval reporting, transient ataxia has been reported following the administration of Drontal Tablets for Cats and Kittens.",{"id":893,"kind":865,"statement":894,"species":11,"limitation":11,"source_label":270},15663,"Isolated incident of either vomiting, bloody stool or watery\u002Fprofuse stool have been reported following treatment. If these signs are observed and they persist, consult your veterinarian.\nQuestions? For questions or to report a suspected side effect, call Durvet, Inc. at 1-800-821-5570.\nFor additional information about reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or http:\u002F\u002Fwww.fda.gov\u002Freportanimalae.",{"id":896,"kind":865,"statement":897,"species":11,"limitation":11,"source_label":706},15664,"None of the 103 dogs treated with Drontal Plus Anthelmintic Tablets in the clinical field studies exhibited drug-related side effects. Of the 40 dogs treated with Drontal Plus Taste Tabs Tablets in laboratory studies, two dogs exhibited vomiting, one puppy exhibited bloody\u002Fmucoid stool and one puppy exhibited watery\u002Fprofuse stool.",{"id":899,"kind":865,"statement":900,"species":11,"limitation":11,"source_label":290},15665,"Seven instances (3.2%) of either vomiting, anorexia, lethargy or diarrhea were reported during the field trials in which 218 dogs were administered Droncit (praziquantel tablets) 34 canine cestocide. The investigators rated these as non-significant.",{"id":902,"kind":865,"statement":903,"species":11,"limitation":11,"source_label":316},15666,"Isolated incident of either salivation, vomiting, diarrhea, poor appetite or listlessness have been reported following treatment, but were considered non-significant. If these signs are observed and they persist, consult your veterinarian.",{"id":905,"kind":865,"statement":906,"species":11,"limitation":11,"source_label":323},15667,"Post-Approval Experience: Although not all adverse reactions are reported, based on voluntary post-approval reporting, transient ataxia has been reported following the administration of Drontal Tablets for Cats and Kittens.",{"id":908,"kind":865,"statement":909,"species":11,"limitation":11,"source_label":339},15668,"Isolated incident of either salivation or diarrhea have been reported following treatment, but were considered non-significant. If these signs are observed and they persist, consult your veterinarian.",{"id":911,"kind":865,"statement":912,"species":11,"limitation":11,"source_label":274},15669,"Isolated incident of either vomiting, bloody stool or watery\u002Fprofuse stool have been reported following treatment. If these signs are observed and they persist, consult your veterinarian.",{"id":914,"kind":865,"statement":915,"species":11,"limitation":11,"source_label":302},15670,"One instance of diarrhea and one of salivation (1.5%) were reported during the field trials in which 135 cats were administered Droncit (praziquantel tablets) 23 Feline Cestocide.",{"id":917,"kind":865,"statement":918,"species":11,"limitation":11,"source_label":728},15671,"Vomiting, loose stools (with or without blood) and decreased activity following treatment. If you notice these signs, contact a veterinarian.",{"id":920,"kind":865,"statement":921,"species":11,"limitation":11,"source_label":270},15672,"None of the 103 dogs treated with Drontal Plus Anthelmintic Tablets in the clinical field studies exhibited drug-related side effects.",{"id":923,"kind":924,"statement":925,"species":11,"limitation":11,"source_label":237},15673,"mechanism_of_action","Mechanism of Action\nCredelio Quattro contains four active pharmaceutical ingredients, lotilaner, moxidectin, praziquantel, and pyrantel (as pamoate salt).\nLotilaner is an ectoparasiticide belonging to the isoxazoline group. Lotilaner inhibits insect and acarine gamma-aminobutyric acid (GABA)-gated chloride channels. This inhibition blocks the transfer of chloride ions across cell membranes, which results in uncontrolled neuromuscular activity leading to death of insects and acarines. The selective toxicity of lotilaner between insects and acarines and mammals may be inferred by the differential sensitivity of the insects and acarines’ GABA receptors versus mammalian GABA receptors.\nMoxidectin is an endectocide in the macrocyclic lactone class. Moxidectin acts by interfering with the chloride channel-mediated neurotransmission in the parasite. This results in paralysis and death of the parasite.\nPraziquantel’s mode of action is not precisely known, but treated tapeworms undergo muscular paralysis accompanied by a rapid influx of calcium ions and the disruption of the tegument.\nPyrantel is a nematocide belonging to the tetrahydropyrimidine class. Pyrantel acts as a depolarizing, neuromuscular-blocking agent in susceptible parasites, causing paralysis and death or expulsion of the parasite.\nPharmacokinetics\nDue to reduced drug bioavailability of lotilaner in the fasted state, Credelio Quattro must be administered with a meal or within 30 minutes after feeding.\nFollowing a single oral administration of Credelio Quattro at the minimum labeled dose in the fed state or a single intravenous administration of 5 mg lotilaner, 0.005 mg moxidectin, 1.25 mg praziquantel, and 1.25 mg pyrantel per kg body weight to Beagle dogs (1.5 to 2.5 years old), the mean oral bioavailability for lotilaner, praziquantel, and pyrantel was 93%, 41%, and 31%, respectively. Bioavailability for moxidectin is not reported due to insufficient data to adequately describe the elimination phase following intravenous administration. For Credelio Quattro, the area under the curve from time of dosing to the time of the last measurable concentration (AUClast) was 5970, 1.75, 1.54, and 0.857 mg*h\u002FL for lotilaner, moxidectin, praziquantel, and pyrantel, respectively. Peak concentrations (Cmax) of 9070, 15.3, 390, and 122 ng\u002FmL were reached (Tmax) 10, 4.5, 0.75, and 2.5 h after dosing for lotilaner, moxidectin, praziquantel, and pyrantel, respectively. Mean plasma elimination half‐lives were 806, 634, 3.64, and 4.87 h for lotilaner, moxidectin, praziquantel, and pyrantel, respectively.\nFollowing nine oral administrations of Credelio Quattro at 1X, 3X, and 5X the maximum labeled dose of 40 mg\u002Fkg lotilaner, 0.04 mg\u002Fkg moxidectin, 10 mg\u002Fkg praziquantel, and 10 mg\u002Fkg pyrantel, every 28 days in 8-week-old Beagle dogs, moxidectin and lotilaner area under the curve from time of dosing to the time of the last measurable concentration (AUClast) increased approximately in a less than proportional manner, whereas praziquantel AUClast increased approximately in a more than proportional manner from 1X to 5X after most study doses. Pyrantel AUClast increased approximately in a proportional manner from 1X to 5X observed after first, sixth, and last doses. Within the 1X group, accumulation was observed between Days 0 and 224 with geometric mean accumulation ratios for AUClast of 6.2 and 7.9 for lotilaner and moxidectin, respectively. Concentrations of praziquantel and pyrantel prior to each dose were below the limit of quantification.",[927],{"id":928,"documentId":929,"slug":930,"name":931},859,"e5e6bwl2jymfkf26sf5vlw3e","anthelmintic","Anthelmintic",[],[],[935,939,944,949,954,959],{"id":936,"documentId":937,"slug":18,"name_en":938,"name_ar":11},848,"k9uwfwxd9rctvv436ks5de96","Fish",{"id":940,"documentId":941,"slug":942,"name_en":943,"name_ar":11},1414,"rvkmhyozs6s1tlfu4ehuopce","dog","Dog",{"id":945,"documentId":946,"slug":947,"name_en":948,"name_ar":11},1425,"gk2ehqoeeinarnk4yz37j5o4","horse","Horse",{"id":950,"documentId":951,"slug":952,"name_en":953,"name_ar":11},1426,"j7o7tp1w2784juwb4te34z5r","domestic-cat","Domestic cat",{"id":955,"documentId":956,"slug":957,"name_en":958,"name_ar":11},1427,"nxuraoydsn1ul47omwk4ofrt","chicken","Chicken",{"id":960,"documentId":961,"slug":962,"name_en":963,"name_ar":11},1439,"t5n3sypt319doki27xt9jx73","sheep","Sheep"]