[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"notifications-list":3,"$f25tb9yir4h6bw":5},{"data":4},[],{"data":6,"error":10},{"id":7,"documentId":8,"slug":9,"name":9,"proprietary_name":10,"non_proprietary_name":10,"is_proprietary":10,"active_ingredient":10,"administration_route":10,"available_strength":10,"dosage_form":10,"dose_schedule":10,"drug_unit":10,"is_available_generically":10,"mechanism_of_action":10,"overdosage":10,"warning":10,"species":11,"citations":12,"dose_schedules":19,"available_strengths":57,"label_statements":81,"drug_classes":114,"specialties":120,"medical_conditions":121,"animal_species":122},1818,"kby5v9s8hyjj4qpyi34ft3wp","tetracaine",null,[],[13],{"source":14,"licence":15,"source_url":16,"harvested_by":17,"retrieved_at":18},"FDA Green Book","US public domain","https:\u002F\u002Fanimaldrugsatfda.fda.gov\u002Fadafda\u002Fapp\u002Fsearch\u002Fpublic\u002FingredientsInformationExcel\u002FSection2ActiveIngredients","load-reference-corpus.cjs","2026-09-07",[20,27,32,37,41,43,45,50,53],{"id":21,"dose_text":22,"species":23,"administration_route":24,"limitation":25,"source_label":26},13352,"In treatment of otitis externa and other inflammatory conditions of the external ear canal a quantity of ointment sufficient to fill the external ear canal may be applied one to three times daily. When used on the skin or mucous membranes, the affected area should be cleansed, and a small amount of the ointment applied and spread or rubbed in gently. The involved area may be treated one to three times a day and these daily applications continued in accordance with the clinical response.","Dogs","Topical","Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Neo-Predef® with Tetracaine Top. Ointment",{"id":28,"dose_text":29,"species":23,"administration_route":24,"limitation":30,"source_label":31},13353,"A quantity of ointment sufficient to fill the external ear canal may be applied one to three times daily.","Tetracaine and neomycin have the potential to sensitize. Care should be taken to observe animals being treated for evidence of hypersensitivity or allergy to the product. If such signs are noted, therapy with the product should be stopped. Incomplete response or exacerbation of corticosteroid responsive lesions may be due to the presence of non susceptible organisms or to prolonged use of antibiotic-containing preparations resulting in overgrowth of non susceptible organisms, particularly Monilia. Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Neo-Cortef® with Tetracaine",{"id":33,"dose_text":34,"species":23,"administration_route":24,"limitation":35,"source_label":36},13354,"2 to 3 applications daily or as needed.","Tetracaine and neomycin have the potential to sensitize. If signs of irritation or sensitivity develop, discontinue use. Prolonged use of this product may result in overgrowth of non-susceptible organisms. If new infections due to bacteria or fungi appear during therapy, appropriate measures should be taken. Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Liquisone F with Cerumene",{"id":38,"dose_text":39,"species":40,"administration_route":24,"limitation":25,"source_label":26},13355,"When used on the skin or mucous membranes, the affected area should be cleansed, and a small amount of the ointment applied and spread or rubbed in gently. The involved area may be treated one to three times a day and these daily applications continued in accordance with the clinical response.","Cats",{"id":42,"dose_text":29,"species":40,"administration_route":24,"limitation":30,"source_label":31},13356,{"id":44,"dose_text":34,"species":40,"administration_route":24,"limitation":35,"source_label":36},13357,{"id":46,"dose_text":47,"species":48,"administration_route":24,"limitation":10,"source_label":49},13358,"After cleaning the affected area, NEO-PREDEF with Tetracaine Powder is applied by compressing the sides of the container with short, sharp squeezes. In the most instances a single daily application will be sufficient; however, it may be applied one to three times daily, as required.","Dogs, cats, and horses","Neo-Predef® with Tetracaine Powder",{"id":51,"dose_text":39,"species":52,"administration_route":24,"limitation":25,"source_label":26},13359,"Horses",{"id":54,"dose_text":55,"species":10,"administration_route":56,"limitation":10,"source_label":49},13360,"After cleansing the affected area, NEO-PREDEF with Tetracaine Powder is applied by compressing the sides of the container with short, sharp squeezes. In most instances a single daily application will be sufficient; however, it may be applied one to three times daily, as required.","TOPICAL",[58,62,64,68,70,74,77,79],{"id":59,"strength_text":60,"dosage_form":61,"proprietary_name":31,"species":23,"source_label":31},11584,"The product contains 5 milligrams of neomycin sulfate, equivalent to 3.5 milligrams of neomycin base, 5 milligrams of hydrocortisone acetate, and 5 milligrams of tetracaine hydrochloride in each gram of ointment.","Ointment",{"id":63,"strength_text":60,"dosage_form":61,"proprietary_name":31,"species":40,"source_label":31},11585,{"id":65,"strength_text":66,"dosage_form":67,"proprietary_name":36,"species":23,"source_label":36},11586,"Each milliliter of suspension contains 5 milligrams neomycin sulfate (equivalent to 3.5 milligrams neomycin base), 2 milligrams prednisolone, 5 milligrams tetracaine, and 0.25 milliliter squalane (hexamethyltetracosane).","Liquid (Suspension)",{"id":69,"strength_text":66,"dosage_form":67,"proprietary_name":36,"species":40,"source_label":36},11587,{"id":71,"strength_text":72,"dosage_form":73,"proprietary_name":49,"species":48,"source_label":49},11588,"NEO-PREDEF with Tetracaine Powder contains in each gram neomycin sulfate, 5 mg (equivalent to 3.5 mg neomycin); isoflupredone acetate, 1 mg; tetracaine hydrochloride, 5 mg; myristyl-gamma-picolinium chloride (as a preservative); and lactose hydrous.","Powder",{"id":75,"strength_text":76,"dosage_form":61,"proprietary_name":26,"species":52,"source_label":26},11589,"The drug contains 5 milligrams of neomycin sulfate (equivalent to 3.5 milligrams of neomycin base), 1 milligram of isoflupredone acetate, and 5 milligrams of tetracaine hydrochloride in each gram of ointment.",{"id":78,"strength_text":76,"dosage_form":61,"proprietary_name":26,"species":23,"source_label":26},11590,{"id":80,"strength_text":76,"dosage_form":61,"proprietary_name":26,"species":40,"source_label":26},11591,[82,86,89,92,95,98,101,104,107,110],{"id":83,"kind":84,"statement":85,"species":23,"limitation":25,"source_label":26},19618,"indication","It is used in treating such conditions as acute otitis externa in dogs and to a lesser degree, chronic otitis externa in dogs. It also is effective in treating anal gland infections and moist dermatitis in the dog and is a useful dressing for minor cuts, lacerations, abrasions, and post-surgical therapy in the dog. It may also be used following amputation of dewclaw, tails and claws, following ear trimming and castrating operations.",{"id":87,"kind":84,"statement":88,"species":23,"limitation":30,"source_label":31},19619,"It is indicated for treating acute otitis externa and, to a lesser degree, chronic otitis externa in dogs. In treatment of ear canker and other inflammatory conditions of the external ear canal.",{"id":90,"kind":84,"statement":91,"species":23,"limitation":35,"source_label":36},19620,"For treating acute otitis externa and as adjunctive therapy in management of chronic otitis externa. Also for treating moist dermatitis in dogs.",{"id":93,"kind":84,"statement":94,"species":40,"limitation":25,"source_label":26},19621,"A useful dressing for minor cuts, lacerations, abrasions, and post-surgical therapy in the cat. It may also be used following amputation of dewclaw, tails and claws, following ear trimming and castrating operations.",{"id":96,"kind":84,"statement":97,"species":40,"limitation":30,"source_label":31},19622,"It is indicated for treating acute otitis externa and, to a lesser degree, chronic otitis externa in cats. In treatment of ear canker and other inflammatory conditions of the external ear canal.",{"id":99,"kind":84,"statement":100,"species":40,"limitation":35,"source_label":36},19623,"For treating acute otitis externa and as adjunctive therapy in management of chronic otitis externa.",{"id":102,"kind":84,"statement":103,"species":48,"limitation":10,"source_label":49},19624,"Indicated in the treatment or adjunctive therapy of certain ear and skin conditions in dogs, cats and horses caused by or associated with neomycin-susceptible organisms and\u002For allergy. In addition, it is indicated as superficial dressing applied to minor cuts, wounds, lacerations, abrasions, and for post-surgical application where reduction of pain and inflammatory response is deemed desirable. NEO-PREDEF with Tetracaine Powder may be used as a dusting powder following amputation of tails, claws, and dew-claws; following ear trimming and castrating; and following such surgical procedure as ovariohysterectomies. Applied superficially, it has been used successfully in the treatment of acute otitis externa in dogs, acute moist dermatitis and interdigital dermatitis in the dog, and as a dusting powder to various minor cuts, lacerations, and abrasions in the horse, cat and dog.",{"id":105,"kind":84,"statement":106,"species":52,"limitation":25,"source_label":26},19625,"A useful dressing for minor cuts, lacerations, abrasions, and post-surgical therapy in the horse. It may also be used following amputation of dewclaw, tails and claws, following ear trimming and castrating operations.",{"id":108,"kind":84,"statement":109,"species":10,"limitation":10,"source_label":49},19626,"NEO-PREDEF with Tetracaine Powder is indicated in the treatment or adjunctive therapy of certain ear and skin conditions in dogs, cats and horses caused by or associated with neomycin-susceptible organisms and\u002For allergy. In addition, it is indicated as superficial dressing applied to minor cuts, wounds, lacerations, abrasions, and for post-surgical application where reduction of pain and inflammatory response is deemed desirable. NEO-PREDEF with Tetracaine Powder may be used as a dusting powder following amputation of tails, claws, and dew-claws; following ear trimming and castrating; and following such surgical procedure as ovariohysterectomies.\nApplied superficially, it has been used successfully in the treatment of acute otitis externa in dogs, acute moist dermatitis and interdigital dermatitis in the dog, and as a dusting powder to various minor cuts, lacerations, and abrasions in the horse, cat and dog.",{"id":111,"kind":112,"statement":113,"species":10,"limitation":10,"source_label":49},19627,"warning","Not for human use. Do not use in horses intended for human consumption.\nClinical and experimental data have demonstrated that corticosteroids administered orally or by injection to animals may induce the first stage of parturition if used during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis.\nAdditionally, corticosteroids administered to dogs, rabbits, and rodents during pregnancy have resulted in cleft palate in offspring. Corticosteroids administered to dogs during pregnancy have also resulted in other congenital anomalies, including deformed forelegs, phocomelia, and anasarca.",[115],{"id":116,"documentId":117,"slug":118,"name":119},826,"e0znz56354ufsh7hargcydcb","sodium-channel-interactions","Sodium Channel Interactions",[],[],[]]