[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"notifications-list":3,"$f1x3ole5risap4":5},{"data":4},[],{"data":6,"error":11},{"id":7,"documentId":8,"slug":9,"name":10,"proprietary_name":11,"non_proprietary_name":11,"is_proprietary":11,"active_ingredient":11,"administration_route":11,"available_strength":11,"dosage_form":11,"dose_schedule":11,"drug_unit":11,"is_available_generically":11,"mechanism_of_action":11,"overdosage":11,"warning":11,"species":12,"citations":13,"dose_schedules":20,"available_strengths":96,"label_statements":133,"drug_classes":210,"specialties":216,"medical_conditions":217,"animal_species":218},1843,"cxwtwl6c7wwh3h6ud106dw4z","vitamin-e","vitamin e",null,[],[14],{"source":15,"licence":16,"source_url":17,"harvested_by":18,"retrieved_at":19},"FDA Green Book","US public domain","https:\u002F\u002Fanimaldrugsatfda.fda.gov\u002Fadafda\u002Fapp\u002Fsearch\u002Fpublic\u002FingredientsInformationExcel\u002FSection2ActiveIngredients","load-reference-corpus.cjs","2026-09-07",[21,28,32,39,44,47,51,55,62,66,72,76,82,87,92],{"id":22,"dose_text":23,"species":24,"administration_route":25,"limitation":26,"source_label":27},13592,"1 milliliter per 200 pounds of body weight in weanling calves. For subcutaneous or intramuscular use.","Cattle (weanling calves)","Subcutaneous, Intramuscular","Discontinue use 30 days before treated cattle are slaughtered for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Velenium™",{"id":29,"dose_text":30,"species":31,"administration_route":25,"limitation":26,"source_label":27},13593,"1 milliliter per 200 pounds of body weight during the middle third of gestation, and 30 days before calving in breeding beef cows. For subcutaneous or intramuscular use.","Cattle (breeding beef cows)",{"id":33,"dose_text":34,"species":35,"administration_route":36,"limitation":37,"source_label":38},13594,"1 mL per 40 lbs body weight (minimum, 1 mL).","Swine (Weanling Pigs)","Intramuscular, Subcutaneous","Anaphylactoid reactions, some of which have been fatal, have been reported in animals administered BO-SE Injection.\nNot for use in newborn pigs.","BO-SE",{"id":40,"dose_text":41,"species":42,"administration_route":36,"limitation":43,"source_label":38},13595,"1 mL per 40 lbs of body weight.","Swine (Sows)","Anaphylactoid reactions, some\nof which have been fatal, have been\nreported in animals administered BO-SE\nInjection.",{"id":45,"dose_text":34,"species":46,"administration_route":36,"limitation":43,"source_label":38},13596,"Sheep (Lambs- 2 weeks of age and older)",{"id":48,"dose_text":49,"species":50,"administration_route":36,"limitation":43,"source_label":38},13597,"2.5 mL per 100 lb body weight.","Sheep (Ewes)",{"id":52,"dose_text":53,"species":54,"administration_route":36,"limitation":43,"source_label":38},13598,"2.5-3.75 mL per 100 lbs of body weight depending on the severity of the condition and geographical area","Cattle (Calves)",{"id":56,"dose_text":57,"species":58,"administration_route":59,"limitation":60,"source_label":61},13599,"The capsules are administered orally with the larger capsules administered at a dosage level of 1 capsule per 20 pounds of body weight to a maximum of 5 capsules with the dosage repeated at 3 day intervals until a satisfactory therapeutic response is observed. A maintenance dosage is then administered consisting of 1 capsule per 40 pounds of body weight, with a minimum of 1 capsule per 40 pounds of body weight, with a minimum of 1 capsule, given every 3 days, or 7 days, or longer, as required to maintain improvement or an asymptomatic condition. For dogs under 20 pounds of body weight, the small capsules are administered orally at a dosage level of 1 per 5 pounds of body weight with a minimum of 1 capsule which dosage is repeated at 3 day intervals until a satisfactory response is observed then a maintenance regimen is initiated with 1 capsule per 10 pounds of body weight, minimum of 1 capsule, every 3 days, or 7 days, or longer as required to maintain continued improvement or an asymptomatic condition.","Dogs","Oral","Federal law restricts this drug to use by or on the order of a licensed veterinarian.","Seletoc® Minicaps and Caps",{"id":63,"dose_text":64,"species":58,"administration_route":36,"limitation":60,"source_label":65},13600,"The drug is administered subcutaneously or intramuscularly in divided doses in 2 or more sites at a dosage level of 1 milliliter per 20 pounds of body weight with a minimum dosage of 1\u002F4 milliliter and a maximum dosage of 5 milliliters. The dosage is repeated at 3 day intervals until a satisfactory therapeutic response is observed. A maintenance regimen is then initiated which consists of 1 milliliter per 40 pounds of body weight with a minimum dosage of 1\u002F4 milliliter which is repeated every 3 days or 7 days or longer, as required to maintain continued improvement or an asymptomatic condition; or the drug may be used in capsule form for oral maintenance therapy.","Seletoc® Injection",{"id":67,"dose_text":68,"species":69,"administration_route":36,"limitation":70,"source_label":71},13601,"1 mL per 200 pounds of body weight during the middle third of pregnancy, and 30 days before calving.","Cattle (Breeding Beef Cattle)","Do not use in adult dairy cattle. Premature births and abortions have been reported in\ndairy cattle injected with this product during the third trimester of pregnancy.","Mu-Se",{"id":73,"dose_text":74,"species":75,"administration_route":36,"limitation":70,"source_label":71},13602,"1 mL per 200 pounds of body weight.","Cattle (Weanling Calves)",{"id":77,"dose_text":78,"species":79,"administration_route":80,"limitation":11,"source_label":81},13603,"1 milliliter per 100 pounds of body weight and may be repeated at 5 to 10 day intervals.","Horses","Intramuscular, Intravenous","E-SE",{"id":83,"dose_text":84,"species":11,"administration_route":85,"limitation":11,"source_label":86},13604,"DOSAGE AND ADMINISTRATION Inject subcutaneously or intramuscularly. Calves: 2.5-3.75 mL per 100 pounds of body weight depending on the severity of the condition and the geographical area. Lambs 2 weeks of age and older: 1 mL per 40 pounds of body weight (minimum, 1 mL). Ewes: 2.5 mL per 100 pounds of body weight. Sows: 1 mL per 40 pounds of body weight. Weanling pigs: 1 mL per 40 pounds of body weight (minimum, 1 mL). Not for use in newborn pigs.","SUBCUTANEOUS, INTRAMUSCULAR","BO-SE® (SELENIUM, VITAMIN E) Injection",{"id":88,"dose_text":89,"species":11,"administration_route":90,"limitation":11,"source_label":91},13605,"DOSAGE AND ADMINISTRATION\nAdministration: slow intravenous injection (see\nWARNINGS\n) or deep intramuscular injections, in divided doses, in two or more sites in the gluteal or cervical muscles. Dosage: 1 mL per 100 pounds of body weight. May be repeated at 5-10 day intervals.","INTRAVENOUS, INTRAMUSCULAR","E-SE® (SELENIUM, VITAMIN E) Injection",{"id":93,"dose_text":94,"species":11,"administration_route":85,"limitation":11,"source_label":95},13606,"DOSAGE AND ADMINISTRATION Inject subcutaneously or intramuscularly. Weanling calves: 1 mL per 200 pounds of body weight. Breeding beef cows: 1 mL per 200 pounds of body weight during the middle third of pregnancy, and 30 days before calving.","MU-SE® (SELENIUM, VITAMIN E) Injection",[97,101,103,107,109,111,113,115,119,122,124,127,130],{"id":98,"strength_text":99,"dosage_form":100,"proprietary_name":27,"species":24,"source_label":27},11845,"Each milliliter contains 10.95 milligrams sodium selenite (equivalent to 5 milligrams selenium), 50 milligrams of vitamin E (68 U.S.P. units).","Liquid (Emulsion)",{"id":102,"strength_text":99,"dosage_form":100,"proprietary_name":27,"species":31,"source_label":27},11846,{"id":104,"strength_text":105,"dosage_form":106,"proprietary_name":38,"species":35,"source_label":38},11847,"Each mL contains: 2.19 mg sodium selenite (equivalent to 1 mg selenium), and 50 mg (68 USP units) vitamin E (as d-alpha tocopheryl acetate).","Liquid",{"id":108,"strength_text":105,"dosage_form":106,"proprietary_name":38,"species":42,"source_label":38},11848,{"id":110,"strength_text":105,"dosage_form":106,"proprietary_name":38,"species":46,"source_label":38},11849,{"id":112,"strength_text":105,"dosage_form":106,"proprietary_name":38,"species":50,"source_label":38},11850,{"id":114,"strength_text":105,"dosage_form":106,"proprietary_name":38,"species":54,"source_label":38},11851,{"id":116,"strength_text":117,"dosage_form":118,"proprietary_name":61,"species":58,"source_label":61},11852,"The capsules contain 2.19 milligrams of sodium selenite (equivalent to 1 milligram of selenium) and 56.2 milligrams of vitamin E (68 I.U.) (as d-alpha tocopheryl acid succinate) or 0.548 milligram of sodium selenite (equivalent to .25 milligram of selenium and 14 milligrams of vitamin E (17 I.U.) (as d-alpha tocopheryl acid succinate.)","Capsule",{"id":120,"strength_text":121,"dosage_form":106,"proprietary_name":71,"species":69,"source_label":71},11853,"Each mL contains: 10.95 mg sodium selenite (equivalent to 5 mg selenium), 50 mg (68 USP units) vitamin E (as (\u002F-alpha tocopheryl acetate), 250 mg polysorbate 80, 2% benzyl alcohol (preservative), water for injection q.s. Sodium hydroxide and\u002For hydrochloric acid may be added to adjust pH.",{"id":123,"strength_text":121,"dosage_form":106,"proprietary_name":71,"species":75,"source_label":71},11854,{"id":125,"strength_text":126,"dosage_form":106,"proprietary_name":81,"species":79,"source_label":81},11855,"Each mL contains: 5.48 milligrams sodium selenite (equivalent to 2.5 milligrams selenium), 50 milligrams of vitamin E (68 I.U.) (as d-alpha tocopheryl acetate)",{"id":128,"strength_text":129,"dosage_form":106,"proprietary_name":65,"species":58,"source_label":65},11856,"The drug contains in each milliliter 2.19 milligrams of sodium selenite (equivalent to 1 milligram of selenium), 50 milligrams of vitamin E (68 I.U.) (as d-alpha tocopheryl acetate), 100 milligrams of polyoxyethylated vegetable oil, 1:10,000 thimerosal, and water for injection.",{"id":131,"strength_text":132,"dosage_form":11,"proprietary_name":11,"species":11,"source_label":95},11857,"68 [USP'U] \u002F 1 mL",[134,138,140,143,145,148,150,152,155,158,161,163,166,169,172,175,178,182,185,189,192,195,198,202,206],{"id":135,"kind":136,"statement":137,"species":24,"limitation":26,"source_label":27},19907,"indication","For the prevention and treatment of selenium-tocopherol deficiency syndrome.",{"id":139,"kind":136,"statement":137,"species":31,"limitation":26,"source_label":27},19908,{"id":141,"kind":136,"statement":142,"species":35,"limitation":37,"source_label":38},19909,"As an aid in the prevention and treatment of diseases associated with Selenium-Tocopherol deficiency, such as hepatic necrosis, mulberry heart disease, and white muscle disease.",{"id":144,"kind":136,"statement":142,"species":42,"limitation":43,"source_label":38},19910,{"id":146,"kind":136,"statement":147,"species":46,"limitation":43,"source_label":38},19911,"For prevention and treatment of white muscle disease (selenium-tocopherol deficiency syndrome).",{"id":149,"kind":136,"statement":147,"species":50,"limitation":43,"source_label":38},19912,{"id":151,"kind":136,"statement":147,"species":54,"limitation":43,"source_label":38},19913,{"id":153,"kind":136,"statement":154,"species":58,"limitation":60,"source_label":65},19914,"The drug is intended for use as an aid in alleviating and controlling inflammation, pain and lameness associated with certain arthropathies in dogs.",{"id":156,"kind":136,"statement":157,"species":58,"limitation":60,"source_label":61},19915,"As an aid in alleviating and controlling inflammation, pain, and lameness associated with certain arthropathies in dogs.",{"id":159,"kind":136,"statement":160,"species":69,"limitation":70,"source_label":71},19916,"MU-SE (selenium, vitamin E) is recommended for the prevention and treatment of STD syndrome.",{"id":162,"kind":136,"statement":160,"species":75,"limitation":70,"source_label":71},19917,{"id":164,"kind":136,"statement":165,"species":79,"limitation":11,"source_label":81},19918,"The drug is intended for use for the prevention and treatment of selenium-tocopherol deficiency syndrome in horses.",{"id":167,"kind":136,"statement":168,"species":11,"limitation":11,"source_label":86},19919,"INDICATIONS BO-SE (selenium, vitamin E) is recommended for the prevention and treatment of white muscle disease (Selenium-Tocopherol Deficiency) syndrome in calves, lambs, and ewes. Clinical signs are: stiffness and lameness, diarrhea and unthriftiness, pulmonary distress and\u002For cardiac arrest. In sows and weanling pigs, as an aid in the prevention and treatment of diseases associated with Selenium-Toco pherol deficiency, such as hepatic necrosis, mulberry heart disease, and white muscle disease. Where known deficiencies of selenium and\u002For vitamin E exist, it is advisable, from the prevention and control standpoint, to inject the sow during the last week of pregnancy.",{"id":170,"kind":136,"statement":171,"species":11,"limitation":11,"source_label":95},19920,"INDICATIONS MU-SE (selenium, vitamin E) is recommended for the prevention and treatment of STD syndrome in weanling calves and breeding beef cattle. Clinical signs are: stiffness and lameness; chronic, persistent diarrhea; unthriftiness; abortions and\u002For weak premature calves.",{"id":173,"kind":136,"statement":174,"species":11,"limitation":11,"source_label":91},19921,"INDICATIONS E-SE Injection is recommended for the control of the following clinical signs when associated with myositis (Selenium-Tocopherol Deficiency) syndrome: rapid respiration, profuse sweating, muscle spasms and stiffness, elevated SGOT.",{"id":176,"kind":136,"statement":177,"species":11,"limitation":11,"source_label":86},19922,"FOR VETERINARY USE ONLY",{"id":179,"kind":180,"statement":181,"species":11,"limitation":11,"source_label":95},19923,"contraindication","CONTRAINDICATION Do not use in adult dairy cattle. Premature births and abortions have been reported in dairy cattle injected with this product during the third trimester of pregnancy.",{"id":183,"kind":180,"statement":184,"species":11,"limitation":11,"source_label":86},19924,"CONTRAINDICATIONS DO NOT USE IN PREGNANT EWES. Deaths and abortions have been reported in pregnant ewes injected with this product.",{"id":186,"kind":187,"statement":188,"species":11,"limitation":11,"source_label":91},19925,"warning","WARNINGS Anaphylactoid reactions, some of which have been fatal, have been reported in horses administered E-SE Injection. Signs include excitement, sweating, trembling, ataxia, respiratory distress, and cardiac dysfunction. These reactions have been reported as associated both with intravenous and intramuscular injections. It is presently unknown whether the mode of application affects the frequency of such reactions. However, reactions associated with intramuscular injections have been reported to manifest more slowly and hence may give more time to institute treatment for anaphylaxis, such as epinephrine and\u002For corticosteroid injection.\nMedications which have been reported to cause major adverse reactions in horses should be avoided when E-SE is administered, unless the condition of the animal requires such use.\nNot to be used in horses intended for food.",{"id":190,"kind":187,"statement":191,"species":11,"limitation":11,"source_label":86},19926,"WARNINGS Anaphylactoid reactions, some of which have been fatal, have been reported in animals administered BO-SE Injection. Signs include excitement, sweating, trembling, ataxia, respiratory distress, and cardiac dysfunction. Selenium- Vitamin E preparations can be toxic when improperly administered.",{"id":193,"kind":187,"statement":194,"species":11,"limitation":11,"source_label":95},19927,"WARNINGS Anaphylactoid reactions, some of which have been fatal, have been reported in cattle administered the MU-SE product. Signs include excitement, sweating, trembling, ataxia, respiratory distress, and cardiac dysfunction.",{"id":196,"kind":187,"statement":197,"species":11,"limitation":11,"source_label":86},19928,"Residue Warnings: Discontinue use 30 days before the treated calves are slaughtered for human consumption. Discontinue use 14 days before the treated lambs, ewes, sows, and pigs are slaughtered for human consumption.",{"id":199,"kind":187,"statement":200,"species":11,"limitation":11,"source_label":201},19929,"FOR USE ON ANIMALS ONLY","Soothex",{"id":203,"kind":204,"statement":205,"species":11,"limitation":11,"source_label":86},19930,"adverse_reaction","ADVERSE REACTIONS Reactions, including acute respiratory distress, frothing from the nose and mouth, bloating, severe depression, abortions, and deaths have occurred in pregnant ewes. Do not use product with phase separation or turbidity.",{"id":207,"kind":208,"statement":209,"species":11,"limitation":11,"source_label":91},19931,"mechanism_of_action","PHARMACOLOGY It has been demonstrated that selenium and tocopherol exert physiological effects and that these effects are intertwined with sulfur metabolism. Additionally, tocopherol appears to have a significant role in the oxidation process, thus suggesting an interrelationship between selenium and tocopherol in overcoming sulfur-induced depletion and restoring normal metabolism. Although oral ingestion of adequate amounts of selenium and tocopherol would seemingly restore normal metabolism, it is apparent that the presence of sulfur and, perhaps, other factors interfere during the digestive process with proper utilization of selenium and tocopherol. When selenium and tocopherol are injected, they bypass the digestive process and exert their full metabolic effects promptly on cell metabolism. Anti-inflammatory action has been demonstrated by selenium-tocopherol in the Selye Pouch Technique and experimentally induced polyarthritis study in rats.",[211],{"id":212,"documentId":213,"slug":214,"name":215},824,"wqjqukzniix941ed01o7gvle","free-radical-scavenging-activity","Free Radical Scavenging Activity",[],[],[]]