[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"notifications-list":3,"$f2oixouj7thsfk":5},{"data":4},[],{"data":6,"error":18},{"id":7,"documentId":8,"slug":9,"title":10,"associated_anatomy":11,"differential_diagnosis":12,"epidemiology":13,"expected_prognosis":14,"pathophysiology":15,"primary_prevention":16,"sign_or_symptom":17,"medical_code":18,"species":19,"citations":28,"is_zoonotic":68,"reservoir":18,"drugs":69,"medical_tests":84,"clinical_signs":85,"animal_species":86},123,"cjkmjqu2zevxweofeb9inwzc","anaplasmosis","Anaplasmosis","Blood (red blood cells, platelets, neutrophils), spleen, liver, gallbladder, lymph nodes, mucous membranes, reproductive tract","In ruminants, babesiosis (causes haemoglobin in urine, which anaplasmosis does not), theileriosis and leptospirosis. In dogs, ehrlichiosis caused by Ehrlichia canis, babesiosis caused by Babesia vogeli and Lyme borreliosis, which often occur as co-infections spread by the same ticks. Confirmation rests on seeing the organism in stained blood smears (inclusions in red cells, platelets or neutrophils), serology or PCR, with sequencing to name the species.","Anaplasma species occur worldwide, especially in tropical and subtropical regions. Ticks are the main vectors: Rhipicephalus and Dermacentor for A. marginale, Rhipicephalus sanguineus for A. platys in dogs and for A. ovis in central Tunisia, and Ixodes ticks for A. phagocytophilum. Biting flies, other insects, reused needles and instruments spread red-cell species mechanically, and transplacental infection is reported. In central Tunisia A. ovis was found in every ewe tested at the first visit and infection built up in lambs over the warm season; in northern Algeria A. marginale was found in 4.0% of 299 clinically ill cattle examined at clinics, peaking in July. A. phagocytophilum and A. platys are zoonotic, with human cases recorded, while A. marginale has not been reported in people. Severity in cattle increases with age.","Most young ruminants recover and become carriers; untreated newly infected adult cattle may suffer 30-50% mortality (Illinois Extension). Tetracyclines are the main treatment class in animals and people and work best when started early.","Anaplasmosis is a group of tick-borne infections caused by obligate intracellular bacteria of the genus Anaplasma (order Rickettsiales), and the species determines which blood cell is attacked. Anaplasma marginale in cattle and A. ovis in sheep and goats live inside red blood cells; the body clears infected and uninfected red cells outside the circulation, producing progressive anaemia and, in cattle, jaundice. A. platys infects platelets in dogs, causing cyclic drops in platelet count through direct damage and immune-mediated destruction. A. phagocytophilum infects neutrophils, lowering white cell and platelet counts in dogs, horses, ruminants and people. Survivors of red-cell infection commonly remain carriers.","Tick control with acaricides during the transmission season, biting-fly control, a new or sterilised needle for every animal, testing animals before they join a herd, and live A. centrale vaccination of calves where permitted.","Ruminants: fever, loss of appetite, pale then yellow mucous membranes, weakness, rapid weight and milk loss, abortion and sometimes sudden death in adult cattle; A. ovis infection in small ruminants is usually subclinical but can cause fever, severe anaemia, weight loss, reduced milk and abortion. Dogs: fever, lethargy, anorexia, enlarged lymph nodes, pale gums, pinpoint bruising and nosebleeds from low platelets. At necropsy in cattle the carcass is anaemic and jaundiced with an enlarged spleen and distended gallbladder.",null,[20,21,22,23,24,25,26,27],"Cattle","Sheep","Goats","Dogs","Cats","Horses","Camels","Humans",[29,36,41,46,50,54,59,64],{"claims":30,"source":31,"licence":32,"source_url":33,"harvested_by":34,"retrieved_at":35},"genus taxonomy, A. marginale in red cells, tick and mechanical vectors, no human infection with A. marginale, distinction from babesiosis, A. centrale vaccine","WOAH Terrestrial Manual 2024 - Chapter 3.4.1 Bovine anaplasmosis","(c) WOAH, free to consult","https:\u002F\u002Fwww.woah.org\u002Ffileadmin\u002FHome\u002Feng\u002FHealth_standards\u002Ftahm\u002F3.04.01_BOVINE_ANAPLASMOSIS.pdf","load-reference-corpus.cjs","2026-09-17",{"claims":37,"source":38,"licence":39,"source_url":40,"harvested_by":34,"retrieved_at":35},"A. phagocytophilum as human pathogen carried by Ixodes ticks, tick prevention, doxycycline as treatment of choice in people","CDC - About Anaplasmosis","not stated on source page (US federal government work)","https:\u002F\u002Fwww.cdc.gov\u002Fanaplasmosis\u002Fabout\u002Findex.html",{"claims":42,"source":43,"licence":44,"source_url":45,"harvested_by":34,"retrieved_at":35},"A. platys and A. phagocytophilum target cells, vectors, host range, clinical signs in dogs, co-infections, tetracyclines, acaricides, zoonotic status","Epidemiology, Diagnosis, and Control of Canine Infectious Cyclic Thrombocytopenia and Granulocytic Anaplasmosis - Europe PMC full text","CC BY 4.0","https:\u002F\u002Fwww.ebi.ac.uk\u002Feuropepmc\u002Fwebservices\u002Frest\u002FPMC8705095\u002FfullTextXML",{"claims":47,"source":48,"licence":44,"source_url":49,"harvested_by":34,"retrieved_at":35},"A. ovis in red cells, signs in small ruminants, Tunisian prevalence and vectors, seasonality","Anaplasma ovis Prevalence Assessment and Cross Validation Using Multiparametric Screening Approach in Sheep from Central Tunisia - Europe PMC full text","https:\u002F\u002Fwww.ebi.ac.uk\u002Feuropepmc\u002Fwebservices\u002Frest\u002FPMC9693597\u002FfullTextXML",{"claims":51,"source":52,"licence":44,"source_url":53,"harvested_by":34,"retrieved_at":35},"A. marginale prevalence and July peak in northern Algeria","Bovine piroplasmosis-anaplasmosis and clinical signs of tropical theileriosis in the plains of Djurdjura (north Algeria) - Europe PMC full text","https:\u002F\u002Fwww.ebi.ac.uk\u002Feuropepmc\u002Fwebservices\u002Frest\u002FPMC7738714\u002FfullTextXML",{"claims":55,"source":56,"licence":57,"source_url":58,"harvested_by":34,"retrieved_at":35},"adult cattle mortality, early tetracycline treatment, clinical signs","University of Illinois Extension - Anaplasmosis (Beef Cattle)","not stated on source page","https:\u002F\u002Fextension.illinois.edu\u002Fbeef-cattle\u002Fanaplasmosis",{"claims":60,"source":61,"licence":62,"source_url":63,"harvested_by":34,"retrieved_at":35},"age-related severity, needle transmission, transplacental carriers, herd-addition testing","Alabama Cooperative Extension System - Bovine Anaplasmosis","(c) 2026 Alabama Cooperative Extension System","https:\u002F\u002Fwww.aces.edu\u002Fblog\u002Ftopics\u002Fbeef\u002Fbovine-anaplasmosis\u002F",{"claims":65,"source":66,"licence":57,"source_url":67,"harvested_by":34,"retrieved_at":35},"confirms A. ovis in sheep and goats, extravascular red-cell destruction, necropsy lesions, ruminant differentials","MSD Veterinary Manual - Anaplasmosis in Ruminants (confirmation only)","https:\u002F\u002Fwww.merckvetmanual.com\u002Fcirculatory-system\u002Fblood-parasites\u002Fanaplasmosis-in-ruminants",true,[70,74,79],{"id":71,"documentId":72,"slug":73,"name":73},1663,"it07okh9q018mzk26lcmwctw","chlortetracycline",{"id":75,"documentId":76,"slug":77,"name":78},1568,"ffmipbw0zab57q6fzpuqjz4s","enrofloxacin","Enrofloxacin",{"id":80,"documentId":81,"slug":82,"name":83},1566,"mobwje6owluqel8b1iwtnnj6","oxytetracycline","Oxytetracycline",[],[],[87,91,96,101,106,111,116],{"id":88,"documentId":89,"slug":90,"name_en":20,"name_ar":18},777,"h9lqv8yrfatdtq0hbnxk1jug","cattle",{"id":92,"documentId":93,"slug":94,"name_en":95,"name_ar":18},790,"jkfqato7h2oc2847wygzmagk","camel","Camel",{"id":97,"documentId":98,"slug":99,"name_en":100,"name_ar":18},1414,"rvkmhyozs6s1tlfu4ehuopce","dog","Dog",{"id":102,"documentId":103,"slug":104,"name_en":105,"name_ar":18},1415,"kb5w3rwizs3rqlt7he1sz639","goat","Goat",{"id":107,"documentId":108,"slug":109,"name_en":110,"name_ar":18},1425,"gk2ehqoeeinarnk4yz37j5o4","horse","Horse",{"id":112,"documentId":113,"slug":114,"name_en":115,"name_ar":18},1426,"j7o7tp1w2784juwb4te34z5r","domestic-cat","Domestic cat",{"id":117,"documentId":118,"slug":119,"name_en":21,"name_ar":18},1439,"t5n3sypt319doki27xt9jx73","sheep"]