كلوكساسيلين

Cattle (lactating cows)

Treatment of mastitis in lactating cows due to Streptococcus agalactiae and Staphylococcus aureus non-penicillinase-producing strains.

Administer after milking, cleaning, and disinfecting, and as early as possible after detection. Treatment should be repeated at 12-hour intervals for a total of three doses. Milk taken from treated animals within 48 hours (4 milkings) after the latest treatment should not be used for food. Treated animals should not be slaughtered for food within 10 days after the latest treatment. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dariclox®

Cattle (Dry Cows)

For the treatment of mastitis in dairy cows during the dry period.

For use in dry cows only. Not to be used within 30 days of calving.

Dry-Clox® Intramammary Infusion

Cattle (dry dairy cows)

Treatment of mastitis caused by Staphylococcus aureus and Streptococcus agalactiae in dairy cows at the time of drying-off of the cow.

For use in dry cows only. Not to be used within 30 days of calving. Milk taken from treated cows prior to 72 hours (6 milkings) after calving must not be used for human food. Animals infused with this product must not be slaughtered for food from the time of infusion until 72 hours after calving. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Boviclox

Cattle (dry cows)

Treatment and prophylaxis of bovine mastitis in nonlactating cows due to Streptococcus agalactiae and Staphylococcus aureus.

For use in dry cows only. Not to be used within 4 weeks (28 days) of calving. Animals infused with this product must not be slaughtered for food use for 4 weeks (28 days) after the latest infusion. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Orbenin DC™

For the treatment of mastitis in dairy cows during the dry period. DRY-CLOX has been shown by extensive clinical studies to be efficacious in the treatment of mastitis in dry cows, when caused by Streptococcus agalactiae and Staphylococcus aureus including penicillin-resistant strains. Treatment of the dry cow with DRY-CLOX is indicated in any cow known to harbor any of these organisms in the udder at drying off, or which has had repeated attacks of mastitis during the previous lactation, or is affected with mastitis at drying off, if caused by susceptible organisms.

Dry-Clox® (cloxacillin benzathine) Intramammary Infusion FOR USE IN DRY COW ONLY

INDICATIONS: Orbenin-DC is indicated in the treatment and prophylaxis of bovine mastitis in nonlactating cows due to Staphylococcus aureus and Streptococcus agalactiae.

Orbenin-DC™ (cloxacillin benzathine intramammary infusion)

CONTRAINDICATIONS: Because cloxacillin benzathine is relatively insoluble, Orbenin-DC's activity will be prolonged. Therefore, Orbenin-DC should not be used for the occasional cow which may have a dry period of less than 4 weeks. This precaution will avoid residues in the milk following removal of the colostrum.

Orbenin-DC™ (cloxacillin benzathine intramammary infusion)

1. For use in dry cows only. 2. Not to be used within 30 days of calving. 3. Any animal infused with this product must not be slaughtered for food until 30 days after the latest infusion.

Dry-Clox® (cloxacillin benzathine) Intramammary Infusion FOR USE IN DRY COW ONLY

WARNINGS: For use in dry cows only. Do not use within 4 weeks (28 days) of calving. Treated animals must not be slaughtered for food purposes within 4 weeks (28 days) of treatment.

Orbenin-DC™ (cloxacillin benzathine intramammary infusion)

Cattle (lactating cows)

10 milliliters (one dose of 200 milligrams) per infected quarter.

Intramammary

Administer after milking, cleaning, and disinfecting, and as early as possible after detection. Treatment should be repeated at 12-hour intervals for a total of three doses. Milk taken from treated animals within 48 hours (4 milkings) after the latest treatment should not be used for food. Treated animals should not be slaughtered for food within 10 days after the latest treatment. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dariclox®

Cattle (Dry Cows)

Infuse the contents of one syringe (10 mL) into each quarter following the last milking.

Intramammary

For use in dry cows only. Not to be used within 30 days of calving.

Dry-Clox® Intramammary Infusion

Cattle (dry dairy cows)

6 milliliters per infected quarter aseptically immediately after the last milking at the time of drying off of the cow.

Intramammary

For use in dry cows only. Not to be used within 30 days of calving. Milk taken from treated cows prior to 72 hours (6 milkings) after calving must not be used for human food. Animals infused with this product must not be slaughtered for food from the time of infusion until 72 hours after calving. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Boviclox

Cattle (dry cows)

One dose per infected quarter immediately after last milking.

Intramammary

For use in dry cows only. Not to be used within 4 weeks (28 days) of calving. Animals infused with this product must not be slaughtered for food use for 4 weeks (28 days) after the latest infusion. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Orbenin DC™

DOSAGE AND ADMINISTRATION: At the last milking of lactation, milk the cow out normally. Clean and disinfect the teats with alcohol swabs provided in the pail and infuse 1 syringe of Orbenin-DC, which has been warmed to room temperature, into each quarter. Do not milk out. The cow may be milked as usual when she calves. The extent of subclinical and latent mastitis in a herd is frequently greater than suspected. In untreated herds a significant buildup of subclinical mastitis may occur during the dry period, which results in clinical severity after a few lactations. The adverse influence of subclinical mastitis on milk yield, the risk of cross-infection, and the chance of clinical mastitis flare-up make it necessary to treat the matter as a herd problem. Clinical studies have proven the value of treating all the cows in heavily infected herds as they are dried off. When the herd infection has been reduced, it may be desirable to be more selective in treating infected quarters. Each pail contains 144 alcohol wipes to facilitate proper cleaning and disinfecting of the teat orifice.

INTRAMAMMARY

Orbenin-DC™ (cloxacillin benzathine intramammary infusion)

DRY-CLOX is for use in dry cows only. Administer immediately after the last milking. Use no later than 30 days prior to calving. Completely milk out all four quarters. The udder and teats should be thoroughly washed with warm water containing a suitable dairy antiseptic and dried, preferably using individual paper towels. Carefully scrub the teat end and orifice with 70% alcohol, using a separate swab for each teat. Allow to dry. DRY-CLOX is packaged with the Opti-Sert® Protective Cap. For partial insertion: Twist off upper portion of the Opti-Sert® Protective Cap to expose 3–4 mm of the syringe tip. For full insertion: Remove protective cap to expose the full length of the syringe tip. Insert syringe tip into the teat canal and expel the entire contents of syringe into the quarter. Withdraw the syringe and gently massage the quarter to distribute the medication. Do not infuse contents of the mastitis syringe into the teat canal if the Opti-Sert® Protective Cap is broken or damaged.

INTRAMAMMARY

Dry-Clox® (cloxacillin benzathine) Intramammary Infusion FOR USE IN DRY COW ONLY

Infuse the contents of one syringe (10 mL) into each quarter following the last milking. See Directions for Use.

INTRAMAMMARY

Dry-Clox® (cloxacillin benzathine) Intramammary Infusion FOR USE IN DRY COW ONLY