mepivacaine

The text below is quoted verbatim from approved veterinary drug labels published by the US FDA (Animal Drugs @ FDA) and DailyMed.

Indications (2)

Horses (1)
  • For use as a local anesthetic for infiltration, nerve block, intra-articular and epidural anesthesia and topical and/or infiltration anesthesia of the laryngeal mucosa prior to ventriculectomy.

    Not for use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

    Carbocaine®-V Sterile Aqueous Solution

Species not stated (1)
  • CARBOCAINE-V Sterile Aqueous Solution is recommended for infiltration, nerve block, intra-articular and epidural anesthesia for horses. It has also been found useful for topical anesthesia of the laryngeal mucosa prior to ventriculectomy. As with other anesthetics, the dosage varies considerably depending on the anesthetic technique, body area to be desensitized and the surgical procedure.

    Carbocaine®-V(mepivacaine hydrochloride injection)Sterile Aqueous Solution

Mechanism of action (1)

Species not stated (1)
  • Mepivacaine hydrochloride is a potent local anesthetic whose effectiveness and safety have been well established in human medicine and dentistry. Laboratory and clinical studies in animals have confirmed its value in veterinary medicine. Its anesthetic activity is two to two and one half times that of procaine, and it is equal to or better than that of lidocaine. The compound has shown excellent tissue compatibility in laboratory animals and in horses. Moderate transient edema at the site of injection may occur in rare instances. CARBOCAINE-V Sterile Aqueous Solution produces rapid and marked local anesthesia lasting for several hours. This enables the veterinarian to proceed with intended manipulations without delay and to complete the work under desensitization which is adequate even for prolonged operations. The innate vasoconstrictive activity of CARBOCAINE-V Sterile Aqueous Solution may be enhanced by the addition of epinephrine at 1:100,000. The addition should be carried out aseptically for current use and any unused portion should be discarded.

    Carbocaine®-V(mepivacaine hydrochloride injection)Sterile Aqueous Solution

Warnings (1)

Species not stated (1)
  • Do not use in horses intended for human consumption. Not for human use. Keep out of reach of children.

    Carbocaine®-V(mepivacaine hydrochloride injection)Sterile Aqueous Solution

Dosage (2)

Horses (1)
  • For nerve block, 3 to 5 milliliters; for epidural anesthesia, 5 to 20 milliliters; for intra-articular anesthesia, 10 to 15 milliliters; for infiltration, as required; for anesthesia of the laryngeal mucosa prior to ventriculectomy by topical spray, 25 to 40 milliliters, by infiltration, 20 to 50 milliliters.

    Epidural, Laryngeal, Infiltration, Intra-Articular

    Not for use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

    Carbocaine®-V Sterile Aqueous Solution

Species not stated (1)
  • Pharmacological studies in various species of animals, including horses, have shown that the drug produces complete and effective anesthesia at dosages that are no more than half those needed when procaine is used. The following dosages have generally proved satisfactory in the horse and are therefore suggested as a guide: For nerve block (diagnosis of lameness, firing, pain relief in osteoarthritis, navicular disease)— 3 to 15 mL For epidural anesthesia (animal standing)— 5 to 20 mL For intra-articular anesthesia (removal of fracture chips, bone and bog spavin, arthritis)— 10 to 15 mL For infiltration (alone or in combination with nerve block or intra-articular anesthesia)— as required For anesthesia of the laryngeal mucosa prior to ventriculectomy CARBOCAINE-V Sterile Aqueous Solution may be administered topically or by infiltration or by a combination of the two. For topical application, a total of 25 to 40 mL applied by spray (3 mL/application) is usually adequate. For infiltration, 20 to 50 mL will suffice.

    EPIDURAL, INFILTRATION, INTRA-ARTICULAR, TOPICAL

    Carbocaine®-V(mepivacaine hydrochloride injection)Sterile Aqueous Solution

Available strengths (2)

ProductDosage formAvailable strengths
Carbocaine®-V Sterile Aqueous SolutionLiquid (Solution)Each milliliter (mL) of solution contains 20 milligrams of mepivacaine hydrochloride.
20 mg / 1 mL